プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Amin A.に依頼

Czech Republic

Specialist in Cytometry, Molecular Biology, Immunology and Molecular diagnostics

プロフィール概要

I have extensive hands-on experience in wet lab techniques across immunology, microbiology, and biotechnology. My expertise includes experimental design, statistical analysis, data visualization, and scientific writing for research publications.

専門分野

• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Mutagenesis
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ Kinases
• ☆ Monoclonal Antibody Production
• ☆ Data Analysis
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Phylogenetics
• ☆ Population Genetics
• ☆ R
• ☆ Medical Genetics
• ☆ Immunogenetics
• ☆ Preventive Medicine
• ☆ Precision Medicine
• ☆ Hematology
• ☆ Leukemia & Lymphoma

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Medical Writing, Technical Writing, General Proofreading & Editing, Translation

Research Meta-Research, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Operations Consulting, Scientific and Technical Consulting, Regulatory Consulting, Manufacturing Consulting

Data & AI Statistical Analysis, Image Processing, Image Analysis, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing

職務経験

Scientific researchers

Charles University in Prague

5月 2025 - 現在

Consultant

La Jolla Institute for Immunology

4月 2023 - 6月 2024

Consultant (postdoctor)

La Jolla Institute for Immunology

4月 2023 - 6月 2024

Project Assistant Professor

Keio University

2月 2021 - 3月 2023

Project Assistant Professor

School of Medicine, Keio University

2月 2021 - 3月 2023

Postdoctor researcher

Tokyo Medical and Dental University

10月 2020 - 1月 2021

学歴

General Medicine (Third Faculty of Medicine)

Charles University

9月 2024 - 現在

Doctor of Philosophy (Immunology)

Tokyo Medical and Dental University

10月 2017 - 9月 2020

Disease Prevention Global Leader Program (Immunology)

Tokyo Medical and Dental University

10月 2017 - 9月 2020

Master's degree (Immunology)

Tokyo Medical and Dental University

10月 2015 - 9月 2017

Master's degree (Biotechnology)

Imam Khomeini International University

9月 2010 - 2月 2013

認定資格

• Certified Specialist in Cytometry

  American Society for Clinical Pathology Board of Certification (ASCP BOC)

  10月 2024 - 現在

• Molecular Diagnostics Technologist

  American Medical Technologists

  https://www.credly.com/badges/3b914943-a871-4aa0-a8e8-01b319d93b73/

  5月 2024 - 現在

出版物

JOURNAL ARTICLE

Analysis of CD22 cis-ligands using a synthetic sialoside binding to CD22 with ultra-high affinity @article{Alborzian_Deh_Sheikh_2025, title={Analysis of CD22 cis-ligands using a synthetic sialoside binding to CD22 with ultra-high affinity}, volume={554}, ISSN={0008-6215}, url={http://dx.doi.org/10.1016/j.carres.2025.109519}, DOI={10.1016/j.carres.2025.109519}, journal={Carbohydrate Research}, publisher={Elsevier BV}, author={Alborzian Deh Sheikh, Amin and Long, Wang and Matsubara, Naoko and Futamura, Takeshi and Imamura, Akihiro and Ando, Hiromune and Ohno, Shiho and Abdu-Allah, Hajjaj H.M. and Takematsu, Hiromu and Asano, Masatake and Yamaguchi, Yoshiki and Ishida, Hideharu and Tsubata, Takeshi}, year={2025}, month=aug, pages={109519} } . Carbohydrate Research.

Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput @article{Kennedy_2024, title={Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput}, volume={21}, ISSN={1548-7105}, url={http://dx.doi.org/10.1038/s41592-024-02256-z}, DOI={10.1038/s41592-024-02256-z}, number={6}, journal={Nature Methods}, publisher={Springer Science and Business Media LLC}, author={Kennedy, Patrick H. and Alborzian Deh Sheikh, Amin and Balakar, Matthew and Jones, Alexander C. and Olive, Meagan E. and Hegde, Mudra and Matias, Maria I. and Pirete, Natan and Burt, Rajan and Levy, Jonathan and Little, Tamia and Hogan, Patrick G. and Liu, David R. and Doench, John G. and Newton, Alexandra C. and Gottschalk, Rachel A. and de Boer, Carl G. and Alarcón, Suzie and Newby, Gregory A. and Myers, Samuel A.}, year={2024}, month=apr, pages={1033–1043} } . Nature Methods.

Chizuru Akatsu, Amin Alborzian Deh Sheikh, Naoko Matsubara, Hiromu Takematsu, Astrid Schweizer, Hajjaj H. M. Abdu-Allah, Thomas F. Tedder, Lars Nitschke, Hideharu Ishida, Takeshi Tsubata(2022). The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45 −/− immunodeficient B cells . Science Signaling. 15. (723). American Association for the Advancement of Science ({AAAS})

Amin Alborzian Deh Sheikh, Chizuru Akatsu, Hajjaj H M Abdu-Allah, Yuki Suganuma, Akihiro Imamura, Hiromune Ando, Hiromu Takematsu, Hideharu Ishida, Takeshi Tsubata (2021). The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells . The Journal of Immunology.

Romain Ballet, Martin Brennan, Carolin Brandl, Ningguo Feng, Jeremy Berri, Julian Cheng, Borja Ocón, Amin Alborzian Deh Sheikh, Alex Marki, Yuhan Bi, et al. (2021). A CD22–Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity . Nature Immunology.

A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides @article{Alborzian_Deh_Sheikh_2021, title={A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides}, volume={116}, ISSN={0896-8411}, url={http://dx.doi.org/10.1016/j.jaut.2020.102571}, DOI={10.1016/j.jaut.2020.102571}, journal={Journal of Autoimmunity}, publisher={Elsevier BV}, author={Alborzian Deh Sheikh, Amin and Gomaa, Soha and Li, Xuexin and Routledge, Matthew and Saigoh, Kazumasa and Numoto, Nobutaka and Angata, Takashi and Hitomi, Yuki and Takematsu, Hiromu and Tsuiji, Makoto and Ito, Nobutoshi and Kusunoki, Susumu and Tsubata, Takeshi}, year={2021}, month=jan, pages={102571} } . Journal of Autoimmunity.

Alborzian Deh Sheikh, A., Akatsu, C., Imamura, A., Abdu-Allah, H.H.M., Takematsu, H., Ando, H., Ishida, H., Tsubata, T.(2018). Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions . Biochemical and Biophysical Research Communications. 495. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 854-859.

Alborzian Deh Sheikh, A., Hosseini, R.(2014). Molecular charcterization of tatD DNAse gene from Ralstonia paucula RA4^T soil bacterium . Applied Biochemistry and Microbiology. 50. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 447-455.

Alborzian Deh Sheikh, A., Moradnejad, M.(2014). Mutagenesis in olive (Olea europaea L.) calli caused by sodium azide and detection of mutants using ISSR and RAPD markers . Journal of Horticultural Science and Biotechnology. 89. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 153-158.

BOOK CHAPTER

Amin Alborzian Deh Sheikh, Chizuru Akatsu, Takeshi Tsubata(2020). Identification of Siglec Cis-Ligands by Proximity Labeling . Methods in Molecular Biology. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 75–83. Springer US