プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Abdullah O.に依頼

United States

Innocentive solver ( 4 awards), Prof of Biochemistry and Clin. Biochem, Biogerontologist, Bioinformatician, 30+y exp, MD

プロフィール概要

I seek opportunities where I can leverage my expertise in aging biology (biogerontology), biochemistry, clinical biochemistry, bioinformatics, and biotech innovation to contribute to basic science, translational medicine, and product development, My key achievements: -Awards: 4 InnoCentive/Wazoku Solver Awards (GlaxoSmithKline, Boehringer Ingelheim, International Rescue Committee); TET Health Innovation Award. -Patents/Products: NephroTesT, UriCollecT, BioAgeCheck, Magoten autoinjector. -Research mainly on aging; published results in many journals (60+ peer-reviewed papers, 900+ citations, i10-index 26, h-index 16 -Founded biotech startup and developed patented diagnostics -Established new Faculty of Pharmacy by designing curriculum, hiring faculty, and launching interdisciplinary research. -Established first hospital diagnostic lab, directed many diagnostic labs, provided evidence based check-up consultancy My education: MD (School of Medicine), Residency/PhD in Biochemistry & Clinical Biochemistry, Masters in Bioinformatics, Completed PhD courses in Pharmaceutical Botany

専門分野

• ☆ Botany
• ☆ Ethnobotany
• ☆ Medicinal Plants
• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Omics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Metabolomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Microinjection
• ☆ Recombinant DNA
• ☆ RNA Synthesis
• ☆ Plasmid DNA
• ☆ Cell Biology
• ☆ Gene Regulation
• ☆ Comparative Physiology
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Agronomy & Crop Science
• ☆ Plant Biotechnology
• ☆ Biological Engineering
• ☆ Data Collection
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Systems Biology
• ☆ Structural Bioinformatics
• ☆ Nutrition Science
• ☆ Vegetarian & Vegan Nutrition
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Decision Science
• ☆ Blotting
• ☆ Cell Aging
• ☆ Recipe Formulation
• ☆ Skin Care & Cosmetology
• ☆ Cognitive Science
• ☆ Psychology of Creativity
• ☆ Gerontology
• ☆ Health Policy
• ☆ Education Policy
• ☆ Medical History
• ☆ Educational Administration
• ☆ Gifted Education
• ☆ Education Reform
• ☆ Science Outreach
• ☆ Educational Counseling
• ☆ Educational Innovation
• ☆ Educational Effectiveness
• ☆ Higher Education
• ☆ Educational Methods & Theories
• ☆ Teacher Education
• ☆ Intellectual Giftedness & Gifted Education
• ☆ Science Education
• ☆ Educational Technology
• ☆ Curriculum Planning & Development
• ☆ Distance Education
• ☆ Military Life
• ☆ Pharmacy
• ☆ Pharmacy Education
• ☆ Clinical Pharmacy
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ Phenotypic Assays
• ☆ Drug Development
• ☆ Preclinical Research
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Vaccine Development
• ☆ Medical Devices
• ☆ Medical Device Development
• ☆ Medical Device Validation
• ☆ Medical Device Design
• ☆ Medical Device Prototyping
• ☆ Medical Device Regulatory Consulting
• ☆ EU In vitro Diagnostic Regulation (IVDR) Compliance
• ☆ In vitro Diagnostics
• ☆ In vitro Diagnostic Validation
• ☆ In vitro Diagnostic Design
• ☆ Point-of-Care Devices
• ☆ Biomarker Analysis
• ☆ Clinical Trials
• ☆ Clinical Trial Design
• ☆ Patient Recruitment
• ☆ Primary Care/Family Medicine
• ☆ Human Biology
• ☆ Neurology
• ☆ Non-Alzheimer's Dementia
• ☆ Parkinson's Disease
• ☆ Alzheimer's Disease
• ☆ Preventive Medicine
• ☆ Precision Medicine
• ☆ Endocrinology
• ☆ Diabetes
• ☆ Hematology
• ☆ Clinical Laboratory Science
• ☆ Clinical Biochemistry
• ☆ Medical Education
• ☆ Continuing Medical Education (CME)
• ☆ Dietetics
• ☆ Healthcare Administration & Management
• ☆ Hospital & Medical Facility Management
• ☆ Healthcare Quality Improvement
• ☆ Complementary & Alternative Medicine
• ☆ Herbal Medicine
• ☆ Traditional Medicine
• ☆ Meditation
• ☆ Alternative Medicine
• ☆ Aromatherapy
• ☆ Occupational Health & Safety
• ☆ Industrial Hygiene
• ☆ Occupational Toxciology
• ☆ Construction Site Safety
• ☆ Workplace Safety Assessment
• ☆ Biofeedback
• ☆ Military Medicine
• ☆ Medical Terminology
• ☆ Medical Sciences
• ☆ Inflammation
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Carcinogenesis
• ☆ Metabolism & Metabolic Disease
• ☆ Medical Equipment & Supplies
• ☆ Vegan Products
• ☆ Product Design
• ☆ Product Prototyping
• ☆ Design for Manufacturing
• ☆ Quality Assurance & Quality Control (QA/QC)
• ☆ Product Validation
• ☆ Concept Development
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Meta-Research
• ☆ Feasibility Studies
• ☆ Technology Scouting
• ☆ Fact Checking
• ☆ Literature Search
• ☆ Gray Literature Search
• ☆ Process Design
• ☆ Instructional Webinars
• ☆ Continuing Medical Education (CME) Training
• ☆ Skills Training
• ☆ Medical Writing
• ☆ Medical Content Writing
• ☆ SEO Medical Writing
• ☆ Continuing Medical Education (CME) Materials
• ☆ Healthcare Communications
• ☆ Patient Education Materials
• ☆ Research Summaries & Abstracts
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Release Notes
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Spec Sheets
• ☆ Case Studies
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Copywriting
• ☆ Product Descriptions
• ☆ User Guides & Handbooks
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Course Content Writing
• ☆ Grant Writing
• ☆ Cosmetic & Skincare Formulation
• ☆ Hair Care Product Formulation
• ☆ Personal Care Product Formulation
• ☆ Cosmetic & Personal Care Product Manufacturing
• ☆ Herbal Products
• ☆ Nutraceuticals
• ☆ Supplements
• ☆ Essential Oils
• ☆ Small Business
• ☆ Entrepreneurship
• ☆ Health Economics
• ☆ Innovation Management
• ☆ Project Management

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Technical Writing, Creative Writing, General Proofreading & Editing, Translation

Research User Research, Meta-Research, Technology Scouting, Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Business Strategy Consulting, Go-to-Market Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting, Manufacturing Consulting

Data & AI Data Insights

Product Development Formulation, Recipe Development, Stability/Shelf Life Testing, Product Evaluation, Product Validation, Manufacturing, Quality Assurance & Control (QA/QC), Concept Development, Product Launch Support, Prototyping, Device Fabrication

職務経験

MLPCARE VM-MP MALTEPE

- 現在

Founder Dean

Istinye University

8月 2017 - 現在

Co-founder and R&D Director

Argeron Medical

12月 2011 - 現在

MD, Specialist

MLPCARE VM-MP MALTEPE

7月 2024 - 9月 2025

Professor and Vice Dean

Altinbas University

2月 2015 - 7月 2017

Head of Hospital Laboratory and Vice Chief Physician

Erzincan Military Hospital

6月 2008 - 9月 2011

Assistant Professor and Associate Professor

Gülhane Military Medical Academy

10月 2000 - 6月 2008

Postdoctoral position

Huffington Center on Aging, Baylor College of Medicine, Houston TX

10月 1999 - 9月 2000

Specialist of Clinical Biochemistry

Sarikamis Military Hospital

12月 1998 - 9月 1999

学歴

Master of Bioinformatics

Ankara University, Institute of Biotechnology

6月 2014 - 6月 2017

Specialist

Gülhane School of Medicine

9月 1995 - 12月 1998

Medical Degree (MD)

Gülhane School of Medicine

9月 1986 - 7月 1992

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Abdullah Olgun, Hanife Abanus, Mutlu Vural, Fahrettin Katkat, Esra Paşaoğlu, Bülent Mert, Udhaya Kumar Siva Kumar (2026). Cellular Senescence in the Ascending Aorta and Complexity of Coronary Atherosclerosis . Journal of Aging Research.

Abdullah Olgun, Berkay Korkmaz, Alev Kural, Ahmet Başman, Bülent Ediz (2025). Effect of vacuum and non-vacuum urine collection systems on urinalysis . Scandinavian Journal of Clinical and Laboratory Investigation.

Abdullah Olgun, Nazmi Savaş, Serdal Öğüt, Elif Yavuz Dokgöz, Meltem Güleç, Ayşegül Çalışkan İşcan (2025). Overview of C.elegans and Investigation of the Effects of Plant Extracts of Lemon Balm (Melissa Officinalis) on the Thermotolerance of Caenorhabditis Elegance . Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi.

Abdullah OLGUN, Margörit Rita KRESPİ ÜLGEN, Hanife Başak ALTUNBEK (2023). The Views of Undergraduate Students and Faculty Members: Distance Education during COVID-19 Pandemic . Research on Education and Psychology.

Alparslan, L., Giray, B., Gulec, M., Kaya, N., Uvey, D., Olgun, A.(2023). Antibacterial and anthelmintic effect of the combination of pomegranate peel and olive leaf extracts . Acta Pharmaceutica Sciencia. 61. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 370-384.

Gunaydin-Akyildiz, A., Yanikoglu, R.S., Gulec, M., Alim-Toraman, G.O., Kuran, E.D., Atasoy, S., Olgun, A., Topcu, G.(2023). Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance . BMC Molecular and Cell Biology. 24. (1).

Şenoğlu, S., Güleç, M., Dokgöz, E.Y., Öztürk, A.B., İzbudak, B., Salih, B., Olgun, A., Ceyhan, T.(2023). Synthesis, characterization, in vitro cytotoxicity of novel metallo phthalocyanines with four methylpropiophenonyl clusters and their effects on Caenorhabditis elegans thermotolerance . Chemical Papers. 77. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1561-1572.

Kovanci, B., Dogan, H., Olgun, A., Kural, A., Yigit, Y., Neijman, S.T.(2023). Urinary trehalase activitiy in contrast-associated acute kidney injury . European Review for Medical and Pharmacological Sciences. 27. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1298-1304.

Olgun, A.(2019). Selective targeting of signet ring cell adenocarcinomas . Medical Hypotheses. 133.

Olgun, A.(2017). “Metformin-resistant” folic acid producing probiotics or folic acid against metformin's adverse effects like diarrhea . Medical Hypotheses. 106. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 33-34.

Yorbik, Ö., Mutlu, C., Özdağ, M.F., Olgun, A., Eryilmaz, G., Ayta, S.(2016). Possible effects of copper and ceruloplasmin levels on auditory event potentials in boys with attention deficit hyperactivity disorder . Noropsikiyatri Arsivi. 53. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 321-327.

Aydın, H.İ, Demirkaya, E., Karadeniz, R.S., Olgun, A., Alpay, F.(2014). Assessing leptin and soluble leptin receptor levels in full-term asymmetric small for gestational age and healthy neonates . The Turkish journal of pediatrics. 56. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 250-258.

Bal, M.V., Olgun, A., Abaslı, D., Özdemir, A., Kürşaklıoğlu, H., Göktepe, A.S., Kurt, Í.(2014). The effect of nonsurgical periodontal treatment on serum and saliva chitotriosidase activities in patients with periodontitis and coronary artery disease . Therapeutics and Clinical Risk Management. 11. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 53-58.

Vural, M., Olgun, A.(2012). Amino acid similarity, between statin binding site of hmg coa reductase and taste perception-related proteins: A possible mechanism for statin-induced taste disorders . Nobel Medicus. 8. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 105-107.

Kilicgun, H., Goksen, G., Olgun, A., Ercisli, S.(2012). Comparison of thermotolerance effects of desferrioxamine and its concentrations in animal model caenorhabditis elegans . Romanian Biotechnological Letters. 17. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7145-7150.

Kundak, A.A., Tascilar, M.E., Abaci, A., Devrim, I., Ozgen, I.T., Demirtek, U., Ozturk, O., Olgun, A., Kurt, I.(2012). Serum chitotriosidase activity: Is it a new infl ammatory marker in obese children ? . Journal of Pediatric Endocrinology and Metabolism. 25. (1-2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 63-67.

Kiliçgün, H., Olgun, A., Köksal, Z.(2011). Investigation of the protective effects of vitamin C, Iron and desferrioxamine on heat stress resistance in the model organism Caenorhabditis elegans . African Journal of Biotechnology. 10. (78). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 18034-18038.

Olgun, A.(2009). Converting NADH to NAD⁺ by nicotinamide nucleotide transhydrogenase as a novel strategy against mitochondrial pathologies during aging . Biogerontology. 10. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 531-534.

Yorbik, O., Ozdag, M.F., Olgun, A., Senol, M.G., Bek, S., Akman, S.(2008). Potential effects of zinc on information processing in boys with attention deficit hyperactivity disorder . Progress in Neuro-Psychopharmacology and Biological Psychiatry. 32. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 662-667.

Olgun, A.(2007). Biological effects of deuteronation: ATP synthase as an example . Theoretical Biology and Medical Modelling. 4.

Aydin, H.I., Yozgat, Y., Demirkaya, E., Olgun, A., Okutan, V., Lenk, M.K., Özcan, O.(2007). Correlation between vascular endothelial growth factor and leptin in children with cyanotic congenital heart disease . Turkish Journal of Pediatrics. 49. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 360-364.

Naharci, M.I., Pinar, M., Bolu, E., Olgun, A.(2007). Effect of testosterone on insulin sensitivity in men with idiopathic hypogonadotropic hypogonadism . Endocrine Practice. 13. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 629-635.

Karaduman, M., Oktenli, C., Musabak, U., Sengul, A., Yesilova, Z., Cingoz, F., Olgun, A., Sanisoglu, S.Y., Baysan, O., Yildiz, O., et al.(2006). Leptin, soluble interleukin-6 receptor, C-reactive protein and soluble vascular cell adhesion molecule-1 levels in human coronary atherosclerotic plaque . Clinical and Experimental Immunology. 143. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 452-457.

Tasci, I., Dogru, T., Sonmez, A., Genc, H., Kilic, S., Olgun, A., Gok, M., Erdem, G., Erikci, S.(2006). Soluble CD40 ligand levels in otherwise healthy subjects with impaired fasting glucose . Mediators of Inflammation. 2006.

Serdar, M.A., Tütüncü, L., Olgun, A., Haşimi, A., Ozgurtaş, T., Erbil, M.K.(2006). The effects of analytical factors on second trimester risk estimations . International Journal of Gynecology and Obstetrics. 93. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 28-32.

Dogru, T., Tasci, I., Sonmez, A., Genc, H., Gok, M., Yilmaz, M.I., Ural, A.U., Olgun, A., Kilic, S., Bozoglu, E., et al.(2006). The plasma levels of soluble P-selectin in subjects with prediabetes . International Journal of Clinical Practice. 60. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1048-1052.

Olgun, A., Aleksenko, T., Pereira-Smith, O.M., Vassilatis, D.K.(2005). Functional analysis of MRG-1: The ortholog of human MRG15 in Caenorhabditis elegans . Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 60. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 543-548.

Olgun, A., Akman, S., Kurt, I., Tuzun, A., Kutluay, T.(2005). MEFV mutations in familial Mediterranean fever: Association of M694V homozygosity with arthritis . Rheumatology International. 25. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 255-259.

Olgun, A., Kisa, O., Yildiran, S.T., Tezcan, S., Akman, S., Erbil, M.K.(2004). Antimicrobial efficacy of L-carnitine . Annals of Microbiology. 54. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 95-101.

Yorbik, O., Olgun, A., Kirmizigül, P., Akman, S.(2004). Plasma zinc and copper levels in boys with oppositional defiant disorder,Karşi Olma Karşi Gelme Bozuklugunda Plazma Cinko ve Bakir Düzeyleri . Turk psikiyatri dergisi = Turkish journal of psychiatry. 15. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 276-281.

Olgun, A., Akman, S., Erbil, M.K.(2004). The role of RBC destruction in vascular regions with high turbulence on atherosclerosis . Medical Hypotheses. 63. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 283-284.

Onur, I., Akman, S., Olgun, A., Fen, T., Kutluay, T.(2003). Peripheral blood telomerase activity in non-Hodgkin lymphoma . Research Communications in Molecular Pathology and Pharmacology. 113-114. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 298-306.

Olgun, A., Akman, S., Tezcan, S., Kutluay, T.(2003). The effect of isoprenoid side chain length of ubiquinone on life span . Medical Hypotheses. 60. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 325-327.

Serdar, M.A., Oguz, O., Olgun, A., Seçkin, B., Ilgan, S., Hasimi, A., Salih, M., Peker, F., Kutluay, T.(2002). Diagnostic approach to prostate cancer using total prostate specific antigen-based parameters together . Annals of Clinical and Laboratory Science. 32. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 22-30.

Tominaga, K., Olgun, A., Smith, J.R., Pereira-Smith, O.M.(2002). Genetics of cellular senescence . Mechanisms of Ageing and Development. 123. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 927-936.

Olgun, A., Akman, S., Serdar, M.A., Kutluay, T.(2002). Oxidative phosphorylation enzyme complexes in caloric restriction . Experimental Gerontology. 37. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 639-645.

Akman, S., Guclu, A., Onkol, M., Olgun, A., Yilmaz, K., Kutluay, T., Arinc, E.(1999). The effect of benzene on serum, hepatic and renal glutathione S transferase, superoxide dismutase, catalase of rat and rabbit . Biochemical Archives. 15. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 239-246.

BOOK CHAPTER

Güleç, M., Kiremitci, S.A., Olgun, A.(2022). Cedrus libani A. Rich . Novel Drug Targets with Traditional Herbal Medicines: Scientific and Clinical Evidence. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 109-119.

OTHER

Senoglu, S., Güleç, M., Dokgöz, E.Y., Öztürk, A.B., İzbudak, B., Salih, B., Olgun, A., Ceyhan, T.(2021). Synthesis, Characterization, in Vitro Cytotoxicity of Novel Metallo Phthalocyanines with Four Methylpropiophenonyl Clusters and Their Effects on Caenorhabditis Elegans Thermotolerance . SSRN.

CONFERENCE PAPER

Vural, M., Olgun, A.(2016). Conference Report: The 2nd Symposium of sudden cardiac arrest survival . Anatolian journal of cardiology. 16. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 457-458.

Saruhan, E., Olgun, A., Öztürk, K., Akman, S., Erbil, M.K.(2007). Age-related paraoxonase activity changes in Turkish population . Annals of the New York Academy of Sciences. 1100. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 218-222.

Kurt, I., Abasli, D., Cihan, M., Serdar, M.A., Olgun, A., Saruhan, E., Erbil, M.K.(2007). Chitotriosidase levels in healthy elderly subjects . Annals of the New York Academy of Sciences. 1100. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 185-188.

Olgun, A., Öztürk, K., Bayir, S., Akman, S., Erbil, M.K.(2007). Deuteronation and aging . Annals of the New York Academy of Sciences. 1100. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 400-403.

Öztürk, K., Olgun, A., Saruhan, E., Ergen, A., Akman, S., Erbil, M.K.(2007). Mitochondrial DNA alterations in aging . Annals of the New York Academy of Sciences. 1100. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 246-249.

Olgun, A., Akman, S.(2007). Mitochondrial DNA-deficient models and aging . Annals of the New York Academy of Sciences. 1100. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 241-245.