プロフィール詳細

プロジェクトを作成

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Dr. Ace S.に依頼

United States

Biochemistry, Microbiology, and Cell Biology expert with 15 years of experience in biotech and academia.

プロフィール概要

I have a PhD in Chemistry and Chemical Biology from Cornell University, focusing on Biophysical Chemistry, a Postdoctoral Research Fellowship in Microbiology and Biochemistry from Harvard Medical School, a teaching position in Biochemistry at UC San Diego, and a Science Communication (IMPACT) Fellowship from MIT. Experienced Ph.D. Biochemist, Biophysicist, and Microbiologist with expertise in elucidating protein and gene function. Adept at solving complex problems using experimental methods of protein biochemistry, transcription regulation, RNA expression, and protein-protein or protein-nucleic acid interactions to understand protein and gene function in cellular physiology. Notable discoveries include transcription regulation and membrane protein assembly mechanisms. Specialized skills: assay development, fluorescence microscopy, immunofluorescence (IF), protein characterization (design/expression/purification/validation), Western blot, molecular biology, microbiology, single-cell analysis, NGS, spatial proteomics, spatial transcriptomics, clinical diagnostics, and computing (MATLAB, R, Python). With these methods, a comprehensive understanding of disease can be achieved to develop more effective and safer therapeutics.

専門分野

• ★ Microbiology
• ★ Biochemistry
• ★ Molecular Biology
• ☆ Binding Assays
• ☆ RNA Sequencing
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Gene Regulation
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Clinical Laboratory Science
• ☆ Clinical Biochemistry

サービス

• Writing
• Research

Writing Medical Writing, Technical Writing

Research Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

職務経験

Postdoctoral Fellow

Harvard Medical School

6月 2017 - 現在

Scientists

10x Genomics

8月 2021 - 10月 2024

Senior Biochemist

Siemens Healthineers

3月 2020 - 8月 2021

Postdoctoral Associate

Cornell University

8月 2016 - 4月 2017

学歴

Master of Science (Chemistry and Chemical Biology)

Cornell University

- 現在

Bachelor of Science (Chemistry)

University of the Philippines Diliman

- 現在

Doctor of Philosophy (Chemistry and Chemical Biology)

Cornell University

- 現在

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Won Jung, Tai-Yen Chen, Ace George Santiago, Peng Chen (2024). Memory effects of transcription regulator−DNA interactions in bacteria . Proceedings of the National Academy of Sciences.

(2017). Adaptor protein mediates dynamic pump assembly for bacterial metal efflux . Proceedings of the National Academy of Sciences.

(2016). Single-molecule dynamics of the molecular chaperone trigger factor in living cells . Molecular Microbiology.

(2015). Quantifying Multistate Cytoplasmic Molecular Diffusion in Bacterial Cells via Inverse Transform of Confined Displacement Distribution . The Journal of Physical Chemistry B.

(2015). Metalloregulator CueR biases RNA polymerase’s kinetic sampling of dead-end or open complex to repress or activate transcription . Proceedings of the National Academy of Sciences.

(2015). Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells . Nature Communications.

(2013). Single-Molecule Dynamics and Mechanisms of Metalloregulators and Metallochaperones . Biochemistry.