プロフィール詳細

プロジェクトを作成

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Dr. Adam Q.に依頼

Australia

Protein chemist with > 9 years of lab experience and proven expertise in scientific literature and grant writing.

プロフィール概要

Expert in molecular biology, protein expression and purification as well as structural biology techniques such as X-ray crystallography and small-angle X-ray scattering. Currently working as a postdoctoral research fellow at Monash University, my current research interests lie in understanding various factors affecting the clot removal pathway in the vascular system and from there, discovering antibody therapeutics to modulate bleeding in trauma. I speak fluent english, mandarin chinese, cantonese and malay.

専門分野

• ★ Antibody Engineering
• ☆ Separation & Purification
• ☆ Recombinant DNA
• ☆ Protein/Enzyme Engineering
• ☆ Experimental Protocols

サービス

• Writing
• Research

Writing Clinical Trial Documentation, Technical Writing

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

職務経験

Postdoctoral Research Fellow

Monash University

7月 2017 - 現在

Research Assistant

Monash University

12月 2010 - 12月 2012

学歴

Doctor of Philosophy

Monash University

1月 2013 - 5月 2017

Bachelor of Biotechnology (Honours)

Monash University

2月 2007 - 10月 2010

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Milena M. Awad, Melanie L. Hutton, Adam J. Quek, William P. Klare, Steven J. Mileto, Kate Mackin, Diane Ly, Viola Oorschot, Marijana Bosnjak, Grant Jenkin, et al.(2020). Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface . Gastroenterology. Elsevier {BV}

(2020). Gas‐Generating, pH‐Responsive Calcium Carbonate Hybrid Particles with Biomimetic Coating for Contrast‐Enhanced Ultrasound Imaging . Particle & Particle Systems Characterization.

(2019). Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes . Journal of structural biology.

(2019). Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding . Journal of molecular biology.

(2019). Structural studies of plasmin inhibition . Biochemical Society transactions.

(2019). Tranexamic acid is an active site inhibitor of urokinase plasminogen activator . Blood advances.

(2017). X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors . Blood advances.

(2015). Preferential Acquisition and Activation of Plasminogen Glycoform II by PAM Positive Group A Streptococcal Isolates . Biochemistry.

(2014). Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain . The Journal of biological chemistry.

(2012). The X-ray crystal structure of full-length human plasminogen . Cell reports.

BOOK CHAPTER

(2020). Toward Better Understanding on How Group A Streptococcus Manipulates Human Fibrinolytic System . Staphylococcus and Streptococcus.