プロフィール詳細

プロジェクトを作成

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Dr. Ahmed K.に依頼

United States

Translational Immunovirologist | Vaccine Design & Neutralizing Antibody Discovery | Preclinical Models & Immune Assays

プロフィール概要

I am an immunovirologist with extensive experience in vaccine development and monoclonal antibody discovery for respiratory viruses, including RSV, influenza, human metapneumovirus (hMPV), and SARS-CoV-2. My work integrates virology, immunology, and translational research to support the development of next-generation vaccines and antibody-based therapeutics. I have hands-on expertise across the full preclinical pipeline, including antigen design, immune profiling, and functional characterization of antibody responses. My technical skillset includes neutralization assays, ELISA and multiplex immunoassays, flow cytometry, single-cell BCR sequencing (10x Genomics), and bio-layer interferometry. I also have experience working with in vivo models (mouse and hamster) to evaluate vaccine efficacy and antibody-mediated protection. My research has contributed to the identification and characterization of broadly neutralizing antibodies and immunodominant epitopes, supported by structural and functional analyses. I regularly collaborate with multidisciplinary teams, including structural biologists and computational scientists, to translate experimental findings into actionable insights for therapeutic and vaccine design. On Kolabtree, I support clients with: Vaccine and immunogen design strategies Monoclonal antibody discovery and characterization Neutralization assay development and data interpretation Immune profiling and flow cytometry panel design Experimental design and troubleshooting Scientific writing, figure development, and manuscript preparation I bring a strong focus on translational impact, clear communication, and timely delivery. Whether you are developing a vaccine candidate, characterizing antibody responses, or preparing a manuscript, I can help move your project forward efficiently.

専門分野

• ☆ Microbiology
• ☆ Virology
• ☆ Molecular Biology
• ☆ Monoclonal Antibody Production
• ☆ Vaccine Development
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ SOP & Protocol Writing
• ☆ Science Communication

サービス

• Research
• Consulting

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

職務経験

Florida State University

2月 2024 - 現在

Lecturer

Zagazig University Faculty of Veterinary Medicine

12月 2021 - 現在

Assistant lecturer

Zagazig University Faculty of Veterinary Medicine

10月 2016 - 現在

Postdoctoral Scientist

Texas Biomedical Research Institute

3月 2022 - 2月 2024

Demonstrator

Zagazig University Faculty of Veterinary Medicine

12月 2013 - 10月 2016

学歴

PhD (The United Graduate School of Veterinary Sciences)

Yamaguchi University

10月 2017 - 9月 2021

Masters (Science)

Zagazig University - Egypt

4月 2014 - 9月 2016

Bachelor of Veterinary Medical Sciences

Zagazig University - Egypt

9月 2008 - 6月 2013

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Noha Saad, Mana Esaki, Isshu Kojima, Ahmed Magdy Khalil, Shiori Osuga, Momtaz A. Shahein, Kosuke Okuya, Makoto Ozawa, Bader Y. Alhatlani (2024). Phylogenetic Characterization of Novel Reassortant 2.3.4.4b H5N8 Highly Pathogenic Avian Influenza Viruses Isolated from Domestic Ducks in Egypt During the Winter Season 2021–2022 . Viruses.

Noha Saad, Mana Esaki, Isshu Kojima, Ahmed Magdy Khalil, Shiori Osuga, Momtaz A. Shahein, Kosuke Okuya, Makoto Ozawa, Bader Y. Alhatlani (2024). Phylogenetic Characterization of Novel Reassortant 2.3.4.4b H5N8 Highly Pathogenic Avian Influenza Viruses Isolated from Domestic Ducks in Egypt During the Winter Season 2021–2022 . Viruses.

Ahmed Magdy Khalil, Mana Esaki, Kosuke Okuya, Makoto Ozawa (2023). Stability of the Virucidal Activity of Commercial Disinfectants against Avian Influenza Viruses under Different Environmental Conditions . Pathogens.

Ahmed Magdy Khalil, Mana Esaki, Kosuke Okuya, Makoto Ozawa (2023). Stability of the Virucidal Activity of Commercial Disinfectants against Avian Influenza Viruses under Different Environmental Conditions . Pathogens.

Ahmed M. Khalil, Michael S. Piepenbrink, Ian Markham, Madhubanti Basu, Luis Martinez-Sobrido, James J. Kobie (2023). Fc-Effector-Independent in vivo Activity of a Potent Influenza B Neuraminidase Broadly Neutralizing Antibody . Viruses.

Ahmed M. Khalil, Michael S. Piepenbrink, Ian Markham, Madhubanti Basu, Luis Martinez-Sobrido, James J. Kobie (2023). Fc-Effector-Independent in vivo Activity of a Potent Influenza B Neuraminidase Broadly Neutralizing Antibody . Viruses.

Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, et al.(2023). Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies . Microbiology Spectrum. American Society for Microbiology

Seyed Arad Moghadasi, Emmanuel Heilmann, Ahmed Magdy Khalil, Christina Nnabuife, Fiona L. Kearns, Chengjin Ye, Sofia N. Moraes, Francesco Costacurta, Morgan A. Esler, Hideki Aihara, et al. (2023). Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors . Science Advances.

Rui P Silva, Yimin Huang, Annalee W Nguyen, Ching-Lin Hsieh, Oladimeji S Olaluwoye, Tamer S Kaoud, Rebecca E Wilen, Ahlam N Qerqez, Jun-Gyu Park, Ahmed M Khalil, et al.(2023). Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses . eLife. 12. {eLife} Sciences Publications, Ltd

Nonoka Matsunaga, Moe Ijiri, Kemi Ishikawa, Makoto Ozawa, Kosuke Okuya, Ahmed Magdy Khalil, Isshu Kojima, Mana Esaki, Tatsunori Masatani, Tsutomu Matsui, et al.(2023). Avian paramyxovirus serotype‐1 isolation from migratory birds and environmental water in southern Japan: an epidemiological survey during the 2018/19–2021/2022 winter seasons . Microbiology and Immunology. Wiley

Ahmed Khalil, Kosuke Okuya, Mana Esaki, Isshu Kojima, Natsuko Nishi, Donna Koyamada, Tsutomu Matsui, Yuuhei Yoshida, Makoto Ozawa (2022). Genetic Characterization of Avian Influenza Viruses Isolated from the Izumi Plain, Japan in 2019/20 Winter Season . Pathogens.

Kosuke Okuya, Ahmed Magdy Khalil, Mana Esaki, Isshu Kojima, Natsuko Nishi, Donna Koyamada, Tsutomu Matsui, Yuuhei Yoshida, Makoto Ozawa (2022). Genetic Characterization of Avian Influenza Viruses Isolated from the Izumi Plain, Japan in 2019/20 Winter Season . Pathogens.

AHMED MAGDY KHALIL(2022). Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody . PLOS Pathogens. 18. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e1010691. Public Library of Science ({PLoS})

Ahmed Magdy Khalil and Isshu Kojima and Wataru Fukunaga and Misuzu Okajima and Sumire Mitarai and Yoshikazu Fujimoto and Tsutomu Matsui and Masakazu Kuwahara and Tatsunori Masatani and Kosuke Okuya and Makoto Ozawa(2022). Improved method for avian influenza virus isolation from environmental water samples . Transboundary and Emerging Diseases. Wiley

Ahmed Magdy Khalil, Hitoshi Hatai, Yoshikazu Fujimoto, Isshu Kojima, Misuzu Okajima, Mana Esaki, Kyonha Kinoshita, Makoto Ozawa (2022). A Lethal Case of Natural Infection with the H5N8 Highly Pathogenic Avian Influenza Virus of Clade 2.3.4.4 in a Mandarin Duck . Zoonotic Diseases.

Ahmed Magdy Khalil, Hitoshi Hatai, Yoshikazu Fujimoto, Isshu Kojima, Misuzu Okajima, Mana Esaki, Kyonha Kinoshita, Makoto Ozawa (2022). A Lethal Case of Natural Infection with the H5N8 Highly Pathogenic Avian Influenza Virus of Clade 2.3.4.4 in a Mandarin Duck . Zoonotic Diseases.

Ahmed Magdy Khalil, Reiko Yoshida, Tatsunori Masatani, Ayato Takada, Makoto Ozawa(2021). Variation in the HA antigenicity of A(H1N1)pdm09-related swine influenza viruses . Journal of General Virology. 102. (3). Microbiology Society

Ahmed Magdy Khalil, Yoshikazu Fujimoto, Isshu Kojima, Mana Esaki, Kyonha Ri, Tatsunori Masatani, Tsutomu Matsui, Makoto Ozawa(2021). Genetic Characterization of H5N8 Highly Pathogenic Avian Influenza Viruses Isolated from Falcated Ducks and Environmental Water in Japan in November 2020 . Pathogens. 10. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 171. {MDPI} {AG}

(2020). Transition in genetic constellations of H3N8 and H4N6 low-pathogenic avian influenza viruses isolated from an overwintering site in Japan throughout different winter seasons . Archives of virology.

Khalil, A.M., Nishi, N., Kojima, I., Fukunaga, W., Kuwahara, M., Masatani, T., Matsui, T., Ozawa, M.(2020). Transition in genetic constellations of H3N8 and H4N6 low-pathogenic avian influenza viruses isolated from an overwintering site in Japan throughout different winter seasons . Archives of Virology. 165. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 643-659.

(2019). Influenza A viruses in birds and humans: Prevalence, molecular characterization, zoonotic significance and risk factors' assessment in poultry farms . Comparative immunology, microbiology and infectious diseases.

Gharieb, R., Mohamed, M., Khalil, A., Ali, A.(2019). Influenza A viruses in birds and humans: Prevalence, molecular characterization, zoonotic significance and risk factors’ assessment in poultry farms . Comparative Immunology, Microbiology and Infectious Diseases. 63. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 51-57.

Ozawa, M., Matsuu, A., Khalil, A.M., Nishi, N., Tokorozaki, K., Masatani, T., Horie, M., Okuya, K., Ueno, K., Kuwahara, M., et al.(2019). Phylogenetic variations of highly pathogenic H5N6 avian influenza viruses isolated from wild birds in the Izumi plain, Japan, during the 2016–17 winter season . Transboundary and Emerging Diseases. 66. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 797-806.

(2018). Phylogenetic variations of highly pathogenic H5N6 avian influenza viruses isolated from wild birds in the Izumi plain, Japan, during the 2016-17 winter season . Transboundary and emerging diseases.