プロフィール詳細

プロジェクトを作成

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Aleksandra J.に依頼

Stem/Cell/Gene therapy expert

プロフィール概要

I am a highly experienced biotechnology professional with nearly two decades of dedicated engagement in developing cancer and rare disease treatments. My career spans a broad spectrum, encompassing translational and clinical research and a comprehensive knowledge of product development and management in the context of cutting-edge medical technologies. My core area of expertise lies in the development of cell therapies, from pioneering proof-of-concept studies to the intricate design of clinical trials. My interests include personalized medicine, personal care, immuno-therapies, and novel cancer detection and treatment technologies. My commitment to science extends beyond the realms of academia and industry; I am also an advocate for disease prevention through the promotion of a healthy lifestyle and exercise, recognizing the profound impact such lifestyle choices can have on individual well-being.

専門分野

• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ PCR
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cytogenetics
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Neuroscience
• ☆ Molecular Neuroscience
• ☆ Histology
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Large Scale Cell Culture
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Biomolecular Engineering
• ☆ Genetic Engineering
• ☆ Immunohistochemistry
• ☆ Tissue Engineering
• ☆ Cytometry
• ☆ Cell Aging
• ☆ Medical Devices
• ☆ Medical Device Development
• ☆ Biocompatibility Testing
• ☆ In vitro Diagnostics
• ☆ Biomarker Analysis

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing

Research Feasibility Study, Technology Scouting, Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Business Strategy Consulting, Operations Consulting, Scientific and Technical Consulting, Regulatory Consulting, Manufacturing Consulting

Data & AI Data Mining, Data Cleaning

Product Development Formulation, Stability/Shelf Life Testing, Product Evaluation, Product Validation, Quality Assurance & Control (QA/QC), Product Compliance , Concept Development, Packaging Design, Prototyping

職務経験

Vice President, Research and Development

AIVITA Biomedical

2月 2016 - 5月 2022

学歴

PhD/Molecular and Cancer Genetics (College of Medicine)

University of Illinois at Chicago

- 現在

認定資格

• PhD

  University of Illinois, Chicago

  1月 2003 - 現在

出版物

JOURNAL ARTICLE

Nistor GI, Robert Dillman, Robles RM, Langford JL, Poole AJ, Sofro MAU, Yett M Nency, Jonny Jonny, Yana ML, Karyana M, et al. (2022). A personal COVID-19 dendritic cell vaccine made at point-of-care: Feasibility, safety, and antigen-specific cellular immune responses . Human vaccines & immunotherapeutics.

Robert Dillman, Nistor GI, Poole AJ (2019). Genomic, proteomic, and immunologic associations with a durable complete remission of measurable metastatic melanoma induced by a patient-specific dendritic cell vaccine . Human vaccines & immunotherapeutics.

Dillman RO, Nistor GI, McLelland BT, Hsieh C, Poole AJ, Cornforth AN, Keirstead HS (2019). Preliminary observations on soluble programmed cell death protein-1 as a prognostic and predictive biomarker in patients with metastatic melanoma treated with patient-specific autologous vaccines . Oncotarget.

Nistor G, Poole AJ, Draelos Z, Lupo M, Tzikas T, Liu JH, Keirstead HS (2016). Human Stem Cell-Derived Skin Progenitors Produce Alpha 2-HS Glycoprotein (Fetuin): A Revolutionary Cosmetic Ingredient. Journal of drugs in dermatology : JDD.

Nistor G, Siegenthaler MM, Poirier SN, Rossi S, Poole AJ, Charlton ME, McNeish JD, Airriess CN, Keirstead HS (2011). Derivation of high purity neuronal progenitors from human embryonic stem cells . PloS one.

Rossi SL, Nistor G, Wyatt T, Yin HZ, Poole AJ, Weiss JH, Gardener MJ, Sipke Dijkstra, David F. Fischer, Keirstead HS (2010). Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord . PloS one.

Carroll RE, Robert Goodlad, Poole AJ, Angela Tyner, R. Brooks Robey, Swanson SM, Unterman TG (2009). Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats . Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Zheng Y, Bie W, Yang R, Perekatt AO, Poole AJ, Tyner AL (2008). Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine . Cancer biology & therapy.

Poole AJ, Li Y, Kim Y, Lin SC, Lee WH, Lee EY (2006). Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist . Science (New York, N.Y.).

Poole AJ, Heap D, Carroll RE, Angela Tyner (2004). Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon . Oncogene.