プロフィール詳細

プロジェクトを作成

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Dr. Allan A.に依頼

United States

Biochemist/chemistry & Academician with over 15+ years of experience

プロフィール概要

Dr. Allan Ayella is Founder, and Chief Scientific Officer for ADEK BioPharma LLC, a consulting firm in chemistry/biochemistry research, food technology, and human nutrition. As an academician, he deeply understands principles of good chemistry/biochemistry, and its application in food technology, human nutrition, and pharmacology. His grasp of USDA/FDA regulations, cGMP, HACCP, and HIPAA gives him an edge in consultancy that requires food, drug, and health applications. Dr. Ayella has used his skill sets to mentor several undergraduate students for the last 15 years. Allan graduated with a second-class upper bachelor’s degree in Biochemistry/Chemistry from Makerere University Kampala in 2001. He was immediately admitted to the Human Genetics program at the University of Leeds, United Kingdom, and the Grain Science program at Kansas State University. He choose to come to United States in 2002 to pursue his Masters in Protein Chemistry in the grain science department at Kansas State University. He continued with his PhD studies in biochemistry and molecular biology by genetically engineering wheat for increased expression of phytochemicals for cancer prevention. Upon graduation, he took up a position as assistant professor of natural sciences, where his primary roles were running the department of natural sciences, grant writing, and teaching science, health and pharmacology courses. During his tenure as a professor of natural sciences, and chemistry he has taught over 8000 students and directly mentored over 300 students in the last 15 – year period. Many of the students he directly mentored have graduated from PhD programs, medical school programs, and other allied health programs. His academic prowess has allowed to allow him to publish several research articles in peer-review scientific journals. Allan’s consultancy in academia is because he understands structures of faculty governance very well. As a previous departmental chair and member of committees, he drafted, several governance policies related to faculty tenure, classroom management, professional development, and research funding. In addition, Dr. Ayella’s research on protein structure and function has been funded by the NIH grants, and other extramural fundings. Over the years, he has managed to attract over a million dollars; a significant amount for small sized institutions where his primary role was teaching. In addition, Dr. Ayella is a prior in developing course undergraduate research courses. Dr. Ayella’s consultancy in industry is backed by his expansive academic experience. His love for applicability of what he does led him to develop ADEK BioPharma LLC, whose main goal is to help solve industrial applications that involve chemistry and biochemistry. To this end, he has patented a unique method for wheat protein extraction. He has developed transgenic wheat that has increased levels of phytochemicals for the prevention of cancer. He has worked with US department of health and human services to draft policies for the dietary recommendations for healthy Americans. In addition, he has helped formulate food products with favorable sensory attributes. Lastly, he helped develop probiotic yogurt product. Dr. Ayella consultancy in health field is due to his academic expertise in pharmacology, and pharmacy applications. Dr. Ayella’s approach to patient care is governed by his love for well – being of the human spirit. His understanding drug function, and usage is governed by his many years of practicing as a nationally certified pharmacy technician. His understanding of medical billing, patient care, customer care, drug dispensing, HIPAA regulations, and other US food and drug related policies.

専門分野

• ★ Biochemistry
• ★ Genetics
• ★ Omics
• ☆ Computational Chemistry
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Proteomics
• ☆ Metabolomics
• ☆ Molecular Evolution
• ☆ PCR
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Recombinant DNA
• ☆ Plasmid DNA
• ☆ Kinases
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Food Chemistry
• ☆ Pharmacy
• ☆ Pharmacy Education
• ☆ Clinical Pharmacy
• ☆ Clinical Trials
• ☆ Clinical Trial Design
• ☆ Patient Recruitment
• ☆ Medical Genetics
• ☆ Immunogenetics
• ☆ Preventive Medicine
• ☆ Regulatory Affairs
• ☆ Medical Terminology

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, General Proofreading & Editing

Research Market Research, User Research, Meta-Research, Feasibility Study, Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting, Regulatory Consulting, Manufacturing Consulting

Data & AI Image Processing, Data Mining, Data Cleaning, Data Processing

Product Development Formulation, Recipe Development, Deformulation, Stability/Shelf Life Testing, Product Evaluation, Manufacturing, Quality Assurance & Control (QA/QC), Product Compliance

職務経験

Assistant Professor

Washburn University

- 現在

ADEK BioPharm LLC

- 現在

Assistant Professor Chemistry

Washburn University

8月 2019 - 4月 2025

学歴

PhD (Biochemistry and Human Nutrition)

Kansas State University

8月 2002 - 8月 2007

PhD (Human Nutrition/Biochemistry)

Kansas State University

8月 2004 - 5月 2007

Msc (Grain Science/Chemistry)

Kansas State University

8月 2002 - 8月 2004

Bsc (Biochemistry/Chemistry)

Makerere University

9月 1998 - 11月 2001

認定資格

• Certified Pharmacy Technician

  National Pharmacy Board

  7月 2025 - 現在

出版物

JOURNAL ARTICLE

Abstract 2434 Exploring Protein-Protein Docking of Sox-2 and HDAC-1 Proteins @article{Ayella_2024, title={Abstract 2434 Exploring Protein-Protein Docking of Sox-2 and HDAC-1 Proteins}, volume={300}, ISSN={0021-9258}, url={http://dx.doi.org/10.1016/j.jbc.2024.107096}, DOI={10.1016/j.jbc.2024.107096}, number={3}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Ayella, Allan and Rorstorm, Carl and Chemani, Perera}, year={2024}, month=mar, pages={107096} } . Journal of Biological Chemistry.

Effects of polar charged amino acids on quantum yield of Tyrosine and Tryptophan @article{Ayella_2021, title={Effects of polar charged amino acids on quantum yield of Tyrosine and Tryptophan}, volume={35}, ISSN={1530-6860}, url={http://dx.doi.org/10.1096/fasebj.2021.35.s1.04790}, DOI={10.1096/fasebj.2021.35.s1.04790}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Ayella, Allan and Pryor, Abigail}, year={2021}, month=may } . The FASEB Journal.

Conserved Tryptophan Mutation Leads to Discovery of Obscure Tyrosinate Fluorescence in Immunoglobulin Domain @article{Vattepu_2020, title={Conserved Tryptophan Mutation Leads to Discovery of Obscure Tyrosinate Fluorescence in Immunoglobulin Domain}, volume={118}, ISSN={0006-3495}, url={http://dx.doi.org/10.1016/j.bpj.2019.11.820}, DOI={10.1016/j.bpj.2019.11.820}, number={3}, journal={Biophysical Journal}, publisher={Elsevier BV}, author={Vattepu, Ravi and Ayella, Allan and Klausmeyer, Rachel and Yadav, Rahul and Dille, Joseph and Beck, Moriah R.}, year={2020}, month=feb, pages={125a–126a} } . Biophysical Journal.

A course‐based undergraduate research experience investigating the consequences of nonconserved mutations in lactate dehydrogenase @article{Ayella_2018, title={A course‐based undergraduate research experience investigating the consequences of nonconserved mutations in lactate dehydrogenase}, volume={46}, ISSN={1539-3429}, url={http://dx.doi.org/10.1002/bmb.21115}, DOI={10.1002/bmb.21115}, number={3}, journal={Biochemistry and Molecular Biology Education}, publisher={Wiley}, author={Ayella, Allan and Beck, Moriah R.}, year={2018}, month=mar, pages={285–296} } . Biochemistry and Molecular Biology Education.

Allan Ayella(2018). Dietary Phytochemicals in Fiber, Fruits and Vegetables, Why is this Still Relevant? . Journal of Nutrition & Food Sciences. 08. (01). OMICS Publishing Group

Improving Personalized Medicine by Examining Structure‐Function Patterns in the Non‐Conserved Regions of Lactate Dehydrogenase (LDH) @article{Alao_2017, title={Improving Personalized Medicine by Examining Structure‐Function Patterns in the Non‐Conserved Regions of Lactate Dehydrogenase (LDH)}, volume={31}, ISSN={1530-6860}, url={http://dx.doi.org/10.1096/fasebj.31.1_supplement.922.5}, DOI={10.1096/fasebj.31.1_supplement.922.5}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Alao, Esther Dami and Ayella, Allan and Beck, Moriah Rene}, year={2017}, month=apr } . The FASEB Journal.

Rheostat or Toggle: Examining the role of non‐conserved mutations to LURE students into research @article{Ayella_2017, title={Rheostat or Toggle: Examining the role of non‐conserved mutations to LURE students into research}, volume={31}, ISSN={1530-6860}, url={http://dx.doi.org/10.1096/fasebj.31.1_supplement.589.3}, DOI={10.1096/fasebj.31.1_supplement.589.3}, number={S1}, journal={The FASEB Journal}, publisher={Wiley}, author={Ayella, Allan Klara and Moriah, Beck R}, year={2017}, month=apr } . The FASEB Journal.

Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside @article{Ayella_2010, title={Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside}, volume={30}, ISSN={0271-5317}, url={http://dx.doi.org/10.1016/j.nutres.2010.10.002}, DOI={10.1016/j.nutres.2010.10.002}, number={11}, journal={Nutrition Research}, publisher={Elsevier BV}, author={Ayella, Allan and Lim, Soyoung and Jiang, Yu and Iwamoto, Takeo and Lin, Dingbo and Tomich, John and Wang, Weiqun}, year={2010}, month=nov, pages={762–769} } . Nutrition Research.

Cancer Preventive Characteristics of Lignan Precursor vs. Lignan Metabolite in Human Colon Cancer SW480 Cells @article{Ayella_2007, title={Cancer Preventive Characteristics of Lignan Precursor vs. Lignan Metabolite in Human Colon Cancer SW480 Cells}, volume={21}, ISSN={1530-6860}, url={http://dx.doi.org/10.1096/fasebj.21.5.a363-c}, DOI={10.1096/fasebj.21.5.a363-c}, number={5}, journal={The FASEB Journal}, publisher={Wiley}, author={Ayella, Allan Klara and Wang, Weiqun}, year={2007}, month=apr } . The FASEB Journal.

Over‐expression of the Lignan Biosynthesis Enzyme in Transgenic Wheat @article{Ayella_2006, title={Over‐expression of the Lignan Biosynthesis Enzyme in Transgenic Wheat}, volume={20}, ISSN={1530-6860}, url={http://dx.doi.org/10.1096/fasebj.20.4.a572-a}, DOI={10.1096/fasebj.20.4.a572-a}, number={4}, journal={The FASEB Journal}, publisher={Wiley}, author={Ayella, Allan Klara and Essig, Juliane S and Schapaugh, Melissa A and Trick, Harold N and Wang, Weiqun}, year={2006}, month=mar } . The FASEB Journal.

OTHER

Wheat Lignans: Promising Cancer Preventive Agents @misc{Wang_2007, title={Wheat Lignans: Promising Cancer Preventive Agents}, ISBN={9780470228333}, url={http://dx.doi.org/10.1002/9780470228333.ch16}, DOI={10.1002/9780470228333.ch16}, journal={Wheat Antioxidants}, publisher={Wiley}, author={Wang, Weiqun and Ayella, Allan and Jiang, Yu and Ouyang, Ping and Qu, Hongyan}, year={2007}, month=jun, pages={264–272} } . Wheat Antioxidants.

Conserved tryptophan mutation disrupts structure and function of immunoglobulin domain revealing unusual tyrosine fluorescence @article{Vattepu_2020, title={Conserved tryptophan mutation disrupts structure and function of immunoglobulin domain revealing unusual tyrosine fluorescence}, url={http://dx.doi.org/10.1101/2020.06.22.165159}, DOI={10.1101/2020.06.22.165159}, publisher={Cold Spring Harbor Laboratory}, author={Vattepu, Ravi and Klausmeyer, Rachel A. and Ayella, Allan and Yadav, Rahul and Dille, Joseph T. and Saiz, Stan V. and Beck, Moriah R.}, year={2020}, month=jun } .