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プロフィール詳細
プロジェクトを作成
★★★★★
☆☆☆☆☆
Dr. Andrew R.に依頼
United States

Associate Professor, CSO and freelance. Next-Generation Sequencing. Bioinformatics, genomics and computational biology.

プロフィール概要
専門分野
サービス
Research User Research, Feasibility Study, Fact Checking, Scientific and Technical Research
職務経験

Assistant Professor

University of Texas Medical Branch at Galveston

11月 2015 - 現在

Post-Doctoral Researcher

Scripps Research Institute

10月 2010 - 8月 2015

学歴

PhD (MRC Laboratory of Molecular Biology)

UNIVERSITY OF CAMBRIDGE

10月 2005 - 8月 2010

MBioc (Lady Margaret Hall)

University of Oxford

2001 - 2005

認定資格
  • 認定資格の詳細は未入力です。
出版物
JOURNAL ARTICLE
Andrew Routh, Stephanea Sotcheff, John Yun-Chung Chen, Nathan Elrod, Jun Cao, Elizabeth Jaworski, Muge N. Kuyumcu-Martinez, Pei-Yong Shi (2022). Zika Virus Infection Alters Gene Expression and Poly-Adenylation Patterns in Placental Cells . Pathogens.
(2020). Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity . The ISME journal.
(2020). Differential Alphavirus Defective RNA Diversity between Intracellular and Extracellular Compartments Is Driven by Subgenomic Recombination Events . mBio.
Andrew Routh, Tiffany Kautz, Elizabeth Jaworski, Naomi L. Forrester (2020). A Low Fidelity Virus Shows Increased Recombination during the Removal of an Alphavirus Reporter Gene . Viruses.
(2020). Understanding Flavivirus Capsid Protein Functions: The Tip of the Iceberg . Pathogens (Basel, Switzerland).
(2020). Mapping RNA-capsid interactions and RNA secondary structure within virus particles using next-generation sequencing . Nucleic acids research.
(2019). Dengue NS2A Protein Orchestrates Virus Assembly . Cell host & microbe.
(2019). Whole-Genome Sequence of Rickettsia parkeri Strain Atlantic Rainforest, Isolated from a Colombian Tick . Microbiology resource announcements.
(2019). DPAC: A Tool for Differential Poly(A)-Cluster Usage from Poly(A)-Targeted RNAseq Data . G3 (Bethesda, Md.).
(2019). Mosquito cells persistently infected with dengue virus produce viral particles with host-dependent replication . Virology.
(2019). Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients . Oncogene.
(2019). Development of Poly(A)-ClickSeq as a tool enabling simultaneous genome-wide poly(A)-site identification and differential expression analysis . Methods (San Diego, Calif.).
(2018). Better Safe than Sorry: A Dual-Function Viral Protein Inhibiting Host Defense . Cell host & microbe.
(2018). ClickSeq: Replacing Fragmentation and Enzymatic Ligation with Click-Chemistry to Prevent Sequence Chimeras . Methods in molecular biology (Clifton, N.J.).
Andrew Routh, Elizabeth Jaworski, Adam S. Lauring(2017). Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus . PLOS Pathogens. 13. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e1006365. Public Library of Science ({PLoS})
Andrew Routh, Ping Ji, Elizabeth Jaworski, Zheng Xia, Wei Li, Eric J. Wagner(2017). Poly(A)-ClickSeq: click-chemistry for next-generation 3΄-end sequencing without RNA enrichment or fragmentation . Nucleic Acids Research. 45. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e112--e112. Oxford University Press ({OUP})
van de Waterbeemd, M., Fort, K.L., Boll, D., Reinhardt-Szyba, M., Routh, A., Makarov, A., Heck, A.J.R.(2017). High-fidelity mass analysis unveils heterogeneity in intact ribosomal particles . Nature Methods.
Barrows, N.J., Campos, R.K., Powell, S.T., Prasanth, K.R., Schott-Lerner, G., Soto-Acosta, R., Galarza-Muñoz, G., McGrath, E.L., Urrabaz-Garza, R., Gao, J., et al.(2016). A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection . Cell Host and Microbe. 20. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 259-270.
Routh, A., Head, S.R., Ordoukhanian, P., Johnson, J.E.(2015). ClickSeq: Fragmentation-Free Next-Generation Sequencing via Click Ligation of Adaptors to Stochastically Terminated 3′-Azido cDNAs . Journal of Molecular Biology. 427. (16). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2610-2616.
Routh, A., Chang, M.W., Okulicz, J.F., Johnson, J.E., Torbett, B.E.(2015). CoVaMa: Co-Variation Mapper for disequilibrium analysis of mutant loci in viral populations using next-generation sequence data . Methods. 91. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 40-47.
Routh, A., Johnson, J.E.(2014). Discovery of functional genomic motifs in viruses with ViReMa-a virus recombination mapper-for analysis of next-generation sequencing data . Nucleic Acids Research. 42. (2).
Routh, A., Domitrovic, T., Johnson, J.E.(2012). Packaging host RNAs in small RNA viruses: An inevitable consequence of an error-prone polymerase? . Cell Cycle. 11. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3713-3714.
Routh, A., Ordoukhanian, P., Johnson, J.E.(2012). Nucleotide-resolution profiling of RNA recombination in the encapsidated genome of a eukaryotic RNA virus by next-generation sequencing . Journal of Molecular Biology. 424. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 257-269.
Routh, A., Domitrovic, T., Johnson, J.E.(2012). Host RNAs, including transposons, are encapsidated by a eukaryotic single-stranded RNA virus . Proceedings of the National Academy of Sciences of the United States of America. 109. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1907-1912.
Andrew Routh, Sara Sandin, Daniela Rhodes(2010). Chromatin Higher Order Structure and Regulation of its Compaction . Biophysical Journal. 98. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 608a. Elsevier {BV}
Neumann, H., Hancock, S.M., Buning, R., Routh, A., Chapman, L., Somers, J., Owen-Hughes, T., van Noort, J., Rhodes, D., Chin, J.W.(2009). A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation . Molecular Cell. 36. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 153-163.
Kruithof, M., Chien, F.-T., Routh, A., Logie, C., Rhodes, D., Van Noort, J.(2009). Single-molecule force spectroscopy reveals a highly compliant helical folding for the 30-nm chromatin fiber . Nature Structural and Molecular Biology. 16. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 534-540.
Robinson, P.J.J., An, W., Routh, A., Martino, F., Chapman, L., Roeder, R.G., Rhodes, D.(2008). 30 nm Chromatin Fibre Decompaction Requires both H4-K16 Acetylation and Linker Histone Eviction . Journal of Molecular Biology. 381. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 816-825.
Routh, A., Sandin, S., Rhodes, D.(2008). Nucleosome repeat length and linker histone stoichiometry determine chromatin fiber structure . Proceedings of the National Academy of Sciences of the United States of America. 105. (26). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8872-8877.
Mehnert, T., Routh, A., Judge, P.J., Lam, Y.H., Fischer, D., Watts, A., Fischer, W.B.(2008). Biophysical characterization of Vpu from HIV-1 suggests a channel-pore dualism . Proteins: Structure, Function and Genetics. 70. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1488-1497.
Mehnert, T., Lam, Y.H., Judge, P.J., Routh, A., Fischer, D., Watts, A., Fischer, W.B.(2007). Towards a mechanism of function of the viral ion channel Vpu from HIV-1 . Journal of Biomolecular Structure and Dynamics. 24. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 589-596.