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プロフィール詳細

プロジェクトを作成

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Dr. Antony M.に依頼

Canada

プロフィール概要

A researcher trained in Neurobiology and genetics. My expertise mostly fall under functional genomics aspects of Central Nervous System (CNS) oncology and disorders. Being trained in Neurobiology for 6 years, I extended my research interest into translating the genomics component of childhood brain tumours (Medulloblastoma and Ependymoma). Functional genomics is fundamental key aspect of therapeutic development for any disease. Currently, I am modelling the cancer genome molecular events of Medulloblastoma and Ependymoma in mouse.

専門分野

• ☆ Developmental Biology
• ☆ Genetics
• ☆ Genomics
• ☆ Neuroscience
• ☆ Neurochemistry
• ☆ Neurobiology

サービス

• Consulting
• Product Development

職務経験

Post Doctoral Fellow

Hospital for Sick Children

10月 2014 - 現在

Research Associate

University of Delhi

5月 2013 - 9月 2014

学歴

Ph.D (Genetics)

University of Delhi

11月 2007 - 4月 2013

MSc Biotechnology (Biotechnology )

University of Madras

7月 2005 - 6月 2007

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2020). Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma . Cell.

Donovan, L.K., Delaidelli, A., Joseph, S.K., Bielamowicz, K., Fousek, K., Holgado, B.L., Manno, A., Srikanthan, D., Gad, A.Z., Van Ommeren, R., et al.(2020). Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma . Nature Medicine.

(2019). Childhood cerebellar tumours mirror conserved fetal transcriptional programs . Nature.

Vladoiu, M.C., El-Hamamy, I., Donovan, L.K., Farooq, H., Holgado, B.L., Sundaravadanam, Y., Ramaswamy, V., Hendrikse, L.D., Kumar, S., Mack, S.C., et al.(2019). Childhood cerebellar tumours mirror conserved fetal transcriptional programs . Nature. 572. (7767). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 67-73.

Mack, S.C., Pajtler, K.W., Chavez, L., Okonechnikov, K., Bertrand, K.C., Wang, X., Erkek, S., Federation, A., Song, A., Lee, C., et al.(2018). Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling . Nature. 553. (7686). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 101-105.

Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, Li Y, Mayoh C, Thiessen N, Mercier E, Mungall KL, Nature, 2016, vol. 529, no. 7586, pp. 351-357 .

Morrissy, A.S., Garzia, L., Shih, D.J.H., Zuyderduyn, S., Huang, X., Skowron, P., Remke, M., Cavalli, F.M.G., Ramaswamy, V., Lindsay, P.E., et al.(2016). Divergent clonal selection dominates medulloblastoma at recurrence . Nature. 529. (7586). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 351-357.

Michealraj, K.A., Jatana, N., Jafurulla, M., Narayanan, L., Chattopadhyay, A., Thelma, B.K.(2014). Functional characterization of rare variants in human dopamine receptor D4 gene by genotype-phenotype correlations . Neuroscience. 262. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 176-189.

Geetha, T.S., Michealraj, K.A., Kabra, M., Kaur, G., Juyal, R.C., Thelma, B.K.(2014). Targeted Deep Resequencing Identifies MID2 Mutation for X-Linked Intellectual Disability with Varied Disease Severity in a Large Kindred from India . Human Mutation. 35. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 41-44.

Ahmad, T., Ahmad, T., Aggarwal, K., Pattnaik, B., Mukherjee, S., Sethi, T., Tiwari, B.K., Kumar, M., Micheal, A., Mabalirajan, U., et al.(2013). Computational classification of mitochondrial shapes reflects stress and redox state . Cell Death and Disease. 4. (1).