プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Ashfaq A.に依頼

Pakistan

PhD Molecular Biology & Bioinformatics | Academic Editor | Manuscript Review, Structural Biology & AI Drug Discovery

プロフィール概要

Dr. Ashfaq Ahmad is a Faculty member of Bioinformatics at Hazara University, Pakistan, with over thirteen years of teaching and research experience. He combines wet-lab experimentation and computational biology, specializing in de novo protein design, drug discovery, and molecular dynamics simulations. His current research explores HER+ cancers, neurological disorders, and the gut-brain axis, integrating AI, deep learning, and structural bioinformatics to accelerate therapeutic innovation. He earned his Ph.D. in Biochemistry and Molecular Biology from Xiamen University, China, and completed a postdoctoral fellowship in Structural Biology and Bioinformatics at the Southern University of Science and Technology, Shenzhen. Dr. Ahmad is the author of “Accelerating Drug Discovery: A Tutorial-Based Approach with Machine Learning” (2023) and has published extensively in high-impact journals, earning recognition among Elsevier and Stanford’s top 2% most productive scientists worldwide (2023). Beyond research, he is an Academic Editor for intl. journal serves on editorial boards, and actively trains the scientific community through workshops and his YouTube channel “Bioinformatics Insights.” His vision is to bridge artificial intelligence and molecular biology to drive transformative advances in healthcare and biotechnology.

専門分野

• ☆ Chemoinformatics
• ☆ Computational Biology
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Structural Bioinformatics

サービス

• Writing
• Research
• Data & AI

Research Meta-Research, Gap Analysis, Scientific and Technical Research

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics

職務経験

Assistant Professor

Hazara University

2月 2019 - 現在

学歴

PhD (Biochemistry and Molecular Biology)

Xiamen University

9月 2011 - 9月 2015

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Ashfaq Ahmad, Sidra Majaz, Dongsheng Liu, Aziz Ud-din, Ikramullah khan, Yu Cui, Yingqiu Xie (2026). Context-Dependent Rewiring of the cGAS-STING Pathway in Cancer: Implications for Immunotherapy and Therapeutic Resistance . Critical Reviews in Oncology/Hematology.

Ashfaq Ahmad, Hamid Ur Rahman, Ihsan Ullah, Noreen Begum, Atta Ur Rehman (2026). Phylogeography and genetic structure of avian isospora based on mitochondrial COI gene sequences from 17 countries . Acta Tropica.

A. Ahmad, S. Majaz, B. Mukhtiar, S. ul Ghafoor, I. Naeem, H. Ur Rahman (2026). Computational analysis of the monkeypox spread on median-joining and maximum parsimony networks . Vacunas.

Ali A, Mashwani ZU, Ahmad A, Luna-Arias JP, Medina-Pérez G (2026). Elucidating the binding mechanism of Caralluma tuberculata metabolites with type 2 diabetes targets through molecular docking and dynamics simulations . PloS one.

Ali, A., Mashwani, Z.-U.-R., Ahmad, A., Luna-Arias, J.P., Medina-Pérez, G., Ahmad, A.(2026). Elucidating the binding mechanism of Caralluma tuberculata metabolites with type 2 diabetes targets through molecular docking and dynamics simulations . Plos One. 21. (4 April).

Rahman, H.U., Ullah, I., Begum, N., Ahmad, A., Rehman, A.U.(2026). Phylogeography and genetic structure of avian isospora based on mitochondrial COI gene sequences from 17 countries . Acta Tropica. 279.

Ashfaq Ahmad (2025). A novel biallelic variant in IHH gene causing Acrocapitofemoral dysplasia in a Pakistani family . Molecular Genetics & Genomic Medicine.

Ashfaq Ahmad, Ahmed S. Abdel-Moneim, Sidra Majaz, Aamir Saeed, Shumaila Noreen, Muhammad Abbas, Bilal Khan, Hamid Ur Rahman, Faisal Nouroz, Yingqiu Xie, et al. (2025). Microevolution and phylogenomic study of Respiratory Syncytial Virus type A . PLOS ONE.

et al., Ahmad, A., Majaz, S., Saeed, A., Noreen, S., Abbas, M., Khan, B., Rahman, H.U., Nouroz, F., Xie, Y., Rashid, A.(2025). Microevolution and phylogenomic study of Respiratory Syncytial Virus type A . Plos One. 20. (2 February).

Saeed, T., Bibi, N., Ahmad, A., Khan, S., Ansar, M., Wasif, N., Kalsoom, U.-E.(2025). A Novel Biallelic Variant in IHH Causing Acrocapitofemoral Dysplasia in a Pakistani Family . Molecular Genetics and Genomic Medicine. 13. (3).

Munir, A., Khan, I.U., Rashid, A., Anwar, I., Shah, S., Oreshkov, S., Ullah, M., Khan, H.A., Ullah, U., Ahmad, A., et al.(2025). A novel homozygous missense variant in POC1B causes cone dystrophy in a consanguineous Pakistani family . Ophthalmic Genetics. 46. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 47-55.

Ashfaq Ahmad, Asad Munir, Inam Ullah Khan, Abdur Rashid, Ijaz Anwar, Sabawoon Shah, Sergey Oreshkov, Mukhtar Ullah, Haider Ali Khan, Ubaid Ullah, et al. (2024). A novel homozygous missense variant in <i>POC1B</i> causes cone dystrophy in a consanguineous Pakistani family . Ophthalmic Genetics.

Ashfaq Ahmad, Haseeb Nisar, Bilal Wajid, Faria Anwar, Anum Javaid, Syed Awais Attique, Wardah Nisar, Amir Saeed, Samiah Shahid, Saima Sadaf (2024). Bioinformatics and systems biology analysis revealed PMID26394986-Compound-10 as potential repurposable drug against covid-19 . Journal of Biomolecular Structure and Dynamics.

Ashfaq Ahmad, Guldan Nazarbek, Chenglin Mu, Ainur Shaimoldina, Zhuldyz Omarova, Nurlan Toktarov, Lian-xiang Wang, Didar Zeitkaziyeva, Haiyan Fan, Lei Shi, et al. (2024). Deer antler extract-nanoparticles exhibit co-nanozyme activity and targeting of prostate cancer cells . Journal of Functional Foods.

Nazarbek, G., Mu, C., Shaimoldina, A., Omarova, Z., Toktarov, N., Wang, L.-X., Ahmad, A., Zeitkaziyeva, D., Fan, H., Shi, L., et al.(2024). Deer antler extract-nanoparticles exhibit co-nanozyme activity and targeting of prostate cancer cells . Journal of Functional Foods. 115.

Nisar, H., Wajid, B., Anwar, F., Ahmad, A., Javaid, A., Attique, S.A., Nisar, W., Saeed, A., Shahid, S., Sadaf, S.(2024). Bioinformatics and systems biology analysis revealed PMID26394986-Compound-10 as potential repurposable drug against covid-19 . Journal of Biomolecular Structure and Dynamics. 42. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7972-7985.

Ashfaq Ahmad, Aliya Orassay, Sidra Majaz, Aamir Saeed, Darya Sadvokassova, Alan Berdigaliyev, Salar Ahmad, Lian-Xiang Wang, Yingqiu Xie (2023). Computational analysis of target genes in monkeypox virus infection and potential therapeutic precursors . Expert Review of Anti-infective Therapy.

Ashfaq Ahmad, Hamid Ur Rahman, Sobia Attaullah, Tariq Mahmood (2023). Distribution, Morphometrics and DNA barcoding of Archotermopsis wroughtoni Desneux (Termopsidae: Blattodea) in District Mansehra, Pakistan . Proceedings of the Pakistan Academy of Sciences: B. Life and Environmental Sciences.

Ashfaq Ahmad, Dongsheng Liu, Aamir Saeed, Sidra Majaz, Bashrat Ahmad, Yingqiu Xie (2023). Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent . Journal of Translational Medicine.

Ashfaq Ahmad, Zhandaulet Makhmutova, Wenwen Cao, Sidra Majaz, Amr Amin, Yingqiu Xie (2023). Androgen receptor, a possible anti-infective therapy target and a potent immune respondent in SARS-CoV-2 spike binding: a computational approach . Expert Review of Anti-infective Therapy.

Liu, D., Saeed, A., Majaz, S., Ahmad, B., Ahmad, A., Xie, Y.(2023). Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent . Journal of Translational Medicine. 21. (1).

Ahmad, A., Orassay, A., Majaz, S., Saeed, A., Sadvokassova, D., Berdigaliyev, A., Ahmad, S., Wang, L.-X., Xie, Y.(2023). Computational analysis of target genes in monkeypox virus infection and potential therapeutic precursors . Expert Review of Anti Infective Therapy. 21. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1153-1161.

Akbar, S., Mohamed, H.G., Ali, H., Saeed, A., Khan, A.A., Gul, S., Ahmad, A., Ali, F., Ghadi, Y.Y., Assam, M.(2023). Identifying Neuropeptides via Evolutionary and Sequential Based Multi-Perspective Descriptors by Incorporation With Ensemble Classification Strategy . IEEE Access. 11. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 49024-49034.

Rahman, H.U., Attaullah, S., Mahmood, T., Ahmad, A.(2023). Distribution, Morphometries and DNA barcoding of Archotermopsis wroughtoni Desneux (Termopsidae: Blattodea) in District Mansehra, Pakistan . Proceedings of the Pakistan Academy of Sciences Part B. 60. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 257-266.

Ahmad, A., Makhmutova, Z., Cao, W., Majaz, S., Amin, A., Xie, Y.(2023). Androgen receptor, a possible anti-infective therapy target and a potent immune respondent in SARS-CoV-2 spike binding: a computational approach . Expert Review of Anti Infective Therapy. 21. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 317-327.

Targeting omicron and other reported SARS-CoV-2 lineages by potent inhibitors of main protease 3CL Mpro: Molecular simulation analysis <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Journal of Infection.

Xin Wang and Jiwen Pan and Liqing Chen and Roushan Li and Yu Han and Zihao Di and Bo Ling and Ashfaq Ahmad and Nuo Yang and Lixia Fan and Qian Li and Jifeng Zeng and Guiying Guo and Jiping Zheng(2022). Prevalence, virulence-related genes and antimicrobial resistance of Aeromonas spp. from loach Misgurnus anguillicaudatus with skin ulcer and healthy controls in Southern China . Aquaculture. 552. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 738040. Elsevier {BV}

(2022). Urgency of COVID-19 vaccination in adolescents: Androgen and estrogen receptors view . Travel medicine and infectious disease.

Kazybay, B., Ahmad, A., Xie, Y.(2022). Urgency of COVID-19 vaccination in adolescents: Androgen and estrogen receptors view . Travel Medicine and Infectious Disease. 47.

Saeed, A., Ahmad, B., Majaz, S., Nouroz, F., Ahmad, A., Xie, Y.(2022). Targeting omicron and other reported SARS-CoV-2 lineages by potent inhibitors of main protease 3CL Mpro: Molecular simulation analysis . Journal of Infection. 84. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e133-e136.

Wang, X., Pan, J., Chen, L., Li, R., Han, Y., Di, Z., Ling, B., Ahmad, A., Yang, N., Fan, L., et al.(2022). Prevalence, virulence-related genes and antimicrobial resistance of Aeromonas spp. from loach Misgurnus anguillicaudatus with skin ulcer and healthy controls in Southern China . Aquaculture. 552.

Kazybay, B., Ahmad, A., Mu, C., Mengdesh, D., Xie, Y.(2022). Omicron N501Y mutation among SARS-CoV-2 lineages: Insilico analysis of potent binding to tyrosine kinase and hypothetical repurposed medicine . Travel Medicine and Infectious Disease. 45.

(2021). Omicron N501Y mutation among SARS-CoV-2 lineages: Insilico analysis of potent binding to tyrosine kinase and hypothetical repurposed medicine . Travel medicine and infectious disease.

Ashfaq Ahmad, Zain Ul Abideen, Muhammad Usman, Sidra Majaz, Waqar Ali, Shumaila Noreen, Tariq Mahmood, Faisal Nouroz(2021). Dynamics and conformational propensities of staphylococcal CntA . Journal of Biomolecular Structure and Dynamics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--13. Informa {UK} Limited

Ashfaq Ahmad, Hamid Ur Rahman, Sidra Majaz, Aamir Saeed(2021). Evolutionary Frequency of Initially Sequenced Human Coronavirus Genomes . Current Trends in OMICS. 1. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--10. University of Management and Technology

Abideen, Z.U., Ahmad, A., Usman, M., Majaz, S., Ali, W., Noreen, S., Mahmood, T., Nouroz, F.(2021). Dynamics and conformational propensities of staphylococcal CntA . Journal of Biomolecular Structure and Dynamics. 39. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4923-4935.

Ma, G., Wang, S., Wu, K., Zhang, W., Ahmad, A., Hao, Q., Lei, X., Zhang, H.(2021). Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors . Bioorganic and Medicinal Chemistry. 29.

(2020). Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors . Bioorganic & medicinal chemistry.

Sidra Majaz, Faisal Nouroz, Ashfaq Ahmad(2020). Two-component systems regulate ABC transporters in antimicrobial peptide production, immunity and resistance . Microbiology. 166. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4--20. Microbiology Society

Ahmad, A., Majaz, S., Nouroz, F.(2020). Two-component systems regulate ABC transporters in antimicrobial peptide production, immunity and resistance . Microbiology United Kingdom. 166. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4-20.

(2018). Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1 . Antimicrobial Agents and Chemotherapy.

(2018). Conformational Hotspots of Dengue Virus NS5 RdRp . Current Bioinformatics.

Khan, F., Ahmad, A., Ali, A., Ali, S.S., Ur Rehman, T.(2018). Conformational hotspots of dengue virus NS5 RdRp . Current Bioinformatics. 13. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 310-318.

Zhang, H., Ma, G., Zhu, Y., Zeng, L., Ahmad, A., Wang, C., Pang, B., Fang, H., Zhao, L., Hao, Q.(2018). Active-site conformational fluctuations promote the enzymatic activity of NDM-1 . Antimicrobial Agents and Chemotherapy. 62. (11).

(2017). Conformational dynamics of the essential sensor histidine kinase WalK . Acta Crystallographica Section D Structural Biology.

Cai, Y., Su, M., Ahmad, A., Hu, X., Sang, J., Kong, L., Chen, X., Wang, C., Shuai, J., Han, A.(2017). Conformational dynamics of the essential sensor histidine kinase WalK . Acta Crystallographica Section D Structural Biology. 73. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 793-803.

(2016). High resolution crystal structure of the catalytic domain of MCR-1 . Scientific Reports.

Ma, G., Zhu, Y., Yu, Z., Ahmad, A., Zhang, H.(2016). High resolution crystal structure of the catalytic domain of MCR-1 . Scientific Reports. 6.

(2015). Conformational Dynamics of Response Regulator RegX3 from Mycobacterium tuberculosis . PLOS ONE.

Ahmad, A., Cai, Y., Chen, X., Shuai, J., Han, A.(2015). Conformational dynamics of response regulator RegX3 from mycobacterium tuberculosis . Plos One. 10. (7).

(2011). Homology Modeling of Ring Necked Pheasant (Phasianus colchicus, Galliformes) Major Hemoglobin Component (HbA). Chemical Society of Pakistan.

(2011). Structural and functional features of Streptolysin O . International Journal of Bioinformatics Research and Applications.

Ashfaq Ahmad, Ali, R., Ghosia Lutfullah, Zahid Khan(2011). Homology modeling of ring necked pheasant (Phasianus colchicus, Galliformes) major hemoglobin component (HbA) . Journal of the Chemical Society of Pakistan. 33. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 539-544.

(2011). Effects of tobacco (smoking and snuffing) in type 2 diabetic patients . International Journal of Food Safety, Nutrition and Public Health.

Lutfuaalah, G., Amjad, A., Amin, F., Ahmad, A.(2011). Homology modeling of bovine kappa-casein . Journal of the Chemical Society of Pakistan. 33. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 433-438.

Ali, R., Lutfullah, G., Khan, Z., Ahmad, A.(2011). Homology modeling of ring necked pheasant (Phasianus Colchicus, Galliformes) minor hemoglobin component . Journal of the Chemical Society of Pakistan. 33. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 379-388.

Ahmad, A., Lutfullah, G., Ali, R.(2011). Structural and functional features of Streptolysin O . International Journal of Bioinformatics Research and Applications. 7. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 427-444.

OTHER

Ahmad, A., Majaz, S., Saeed, A., Noureen, S., Rahman, H.U., Nouroz, F., Xie, Y., Amin, A.(2024). Microevolution and phylogenomic characterization of Respiratory Syncytial Virus Type A: An outlook of 2022-2023 outbreak . Research Square.

Ahmad, A., Majaz, S., Saeed, A., Noureen, S., Ur Rahman, H., Nouroz, F., Amin, A., Xie, Y.(2023). Microevolution and Phylogenomic Characterization of Respiratory Syncytial Virus Type A: An Outlook of 2022-2023 Outbreak . Ssrn.

Majaz, S., Ahmad, A., Saeed, A., Noureen, S., Nouroz, F., Amin, A., Xie, Y.(2023). Microevolution and phylogenomic characterization with perspectives in the 2022-2023 outbreak of child Respiratory Syncytial Virus type A . Biorxiv.

Ahmad, A., Majaz, S., Saeed, A., Noureen, S., Nouroz, F., Ur Rahman, H., Amin, A., Xie, Y.(2023). Microevolution and Phylogenomic Characterization of Respiratory Syncytial Virus Type A: An Outlook of 2022-2023 Outbreak . Ssrn.

Wang, X., Pan, J., Chen, L., Li, R., Han, Y., Di, Z., Ling, B., Ahmad, A., Yang, N., Fan, L., et al.(2021). Isolation, identification and molecular characterization of Aeromonas spp. From farmed loach (Misgurnus anguillicaudatus) . Biorxiv.

Ahmad, A., Majaz, S., Nouroz, F.(2020). Evolutionary Frequency of the Available Human Coronavirus Genomes . Research Square.

PREPRINT

Ashfaq Ahmad, Sidra Majaz, Aamir Saeed, Shumaila Noureen, Faisal Nouroz, Amr Amin, Yingqiu Xie (2023). Microevolution and phylogenomic characterization with perspectives in the 2022-2023 outbreak of child Respiratory Syncytial Virus type A .

Ashfaq Ahmad, Sidra Majaz, Faisal Nouroz (2020). Evolutionary Frequency of the Available Human Coronavirus Genomes .