プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Binay S.に依頼

United States

Scientific Consultant | Single-Cell, Proteomics, Antibody & Cell Line Engineering

プロフィール概要

I am a PhD-trained molecular and cancer biologist with 15+ years of experience supporting translational research, drug discovery, and high-impact publications. I work with academic labs, biotech startups, and industry teams to analyze multi-omics datasets and connect them to experimental strategy and therapeutic decisions. My work spans single-cell genomics, proteomics, protein/antibody engineering, and functional validation, so I can support projects from hypothesis to data to next-step experiments. Core expertise • Single-cell RNA-seq and CITE-seq analysis (Seurat, TotalSeq; mouse and human) • Bulk RNA-seq analysis and integrated multi-omics interpretation • Proteomics data analysis (LC-MS/MS, BioID proximity labeling, LFQ, volcano plots, pathway enrichment) • Protein and antibody engineering support (target rationale, construct design strategy, developability considerations, and assay planning for validation) • Cell line engineering (stable/inducible expression systems, CRISPR/Cas9 strategy design at the conceptual level, screening/validation planning, and functional readouts) • Multicolor flow cytometry (FACS): panel design, compensation, gating strategies, and data interpretation Scientific consulting and advisory • Grant writing and editing (Specific Aims, fellowship proposals, project proposals) • Independent project and data review (study design, figures, statistical logic, biological conclusions) • Manuscript editing and reviewer-response support, focused on clarity and rigor • Translational guidance linking mechanistic biology to therapeutic relevance Clients typically hire me to deliver reproducible analysis + publication-ready figures, and to provide clear, defensible interpretation with practical next experiments. I communicate clearly, respect timelines, and prioritize scientific rigor over over-interpretation. I am comfortable working under NDA and collaborating with multidisciplinary teams.

専門分野

• ★ Molecular Biology
• ★ Omics
• ★ Cytometry
• ☆ Biomarkers
• ☆ Genetics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Proteomics
• ☆ Genomics
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ ATAC-Seq
• ☆ DNA Sequencing
• ☆ Synthetic Genomics
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Mutagenesis
• ☆ Exome Sequencing
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ ChIP-Seq
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytogenetics
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Data Analysis
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Systems Biology
• ☆ Structural Bioinformatics
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Cell Surface Receptors
• ☆ Biomolecular Engineering
• ☆ Gene Editing/CRISPR
• ☆ Protein/Enzyme Engineering
• ☆ Antibody Engineering
• ☆ Gene Delivery
• ☆ Blotting
• ☆ R
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ Dentistry
• ☆ Dental Research
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Quantitative User Research
• ☆ Qualitative User Research
• ☆ Feasibility Studies
• ☆ Fact Checking
• ☆ Literature Search
• ☆ Gap Analysis
• ☆ Presentation Design

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Technical Writing

Research Meta-Research, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Data Mining

Product Development Formulation, Product Evaluation, Quality Assurance & Control (QA/QC), Concept Development

職務経験

Faculty Scientist

University of Vermont

2月 2026 - 現在

Postdoc

Stanford University

2月 2023 - 2月 2026

PhD candidate

Academia Sinica

9月 2015 - 1月 2023

Research Assistant/Teaching Assistant

CDFD

6月 2010 - 9月 2015

学歴

PhD Molecular Medicine

Academia Sinica

9月 2015 - 7月 2022

認定資格

• PhD

  Academia Sinica, Taiwan

  7月 2022 - 現在

出版物

JOURNAL ARTICLE

Binay Sahoo, Elizabeth A. R. Garfinkle, Pratima Nallagatla, Jinjun Dang, Mohammad Balood, Anitria Cotton, Camryn Franke, Sharnise Mitchell, Taylor Wilson, Tanja A. Gruber (2024). CBFA2T3-GLIS2 mediates transcriptional regulation of developmental pathways through a gene regulatory network . Nature Communications.

Binay Sahoo, Elizabeth A Garfinkle, Pratima Nallagatla, Jinjun Dang, Mohammad Balood, Anitria Cotton, Camryn Franke, Sharnise Mitchell, Taylor Wilson, Tanja A Gruber(2024). CBFA2T3-GLIS2 mediates transcriptional regulation of developmental pathways through a gene regulatory network . Nature communications. 15. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8747.

Yuh-Charn Lin, Binay K. Sahoo, Shiang-Shin Gau, Ruey-Bing Yang(2023). The biology of SCUBE . Journal of Biomedical Science. 30. (1). Springer Science and Business Media {LLC}

Binay K. Sahoo, Yuh-Charn Lin, Cheng-Fen Tu, Chien-Chin Lin, Wei-Ju Liao, Fu-An Li, Ling-Hui Li, Kurt Yun Mou, Steve R. Roffler, Shu-Ping Wang, et al.(2022). Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia . Haematologica. 108. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1284--1299. Ferrata Storti Foundation (Haematologica)

Mokhamatam, Raveendra B., Sahoo, Binay K., Manna, Sunil K.(2016). Suppression of microphthalmia-associated transcription factor, but not NF-kappa B sensitizes melanoma specific cell death . Apoptosis. 21. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 928-940.

Sahoo, Binay K., Zaidi, Adeel H., Gupta, Pankaj, Mokhamatam, Raveendra B., Raviprakash, Nune, Mahali, Sidhartha K., Manna, Sunil K.(2015). A natural xanthone increases catalase activity but decreases NF-kappa B and lipid peroxidation in U-937 and HepG2 cell lines . European Journal of Pharmacology. 764. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 520-528.