プロフィール詳細

プロジェクトを作成

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Dr. Beatriz B.に依頼

Germany

Regulatory Consultant with 8+ years of experience in Medicinal Chemistry

プロフィール概要

Dr Beatriz Blanco Rodríguez earned her B. Sc. (Organic Chemistry) and M. Sc. degrees (Advanced Chemistry) at the University of Santiago de Compostela in Spain. She gained her PhD on the Development of New Antimicrobials as Inhibitors of Shikimate Kinase and Type II Dehydroquinase at the same university in 2013 under the supervision of Prof. Concepción González-Bello. During her PhD studies, she did one predoctoral internship at the Scripps Research Institute (La Jolla, USA, 2011) with Prof. Kim D. Janda on the Synthesis and biological evaluation of inhibitors for Botulinum neurotoxin A light chain. In 2014 she moved to the Canterbury (UK) and gained working experience in industry (Peakdale Molecular Services). After that, she moved to Adelaide (Australia) where she undertook her postdoc research on inhibitors of Biotin Protein Ligase and Protease inhibitors under the supervision of Prof. Andrew Abell.

専門分野

• ★ Organic Chemistry
• ★ Product Compliance
• ☆ Clinical Trials

サービス

• Writing
• Research

Writing Clinical Trial Documentation, Technical Writing

Research Systematic Literature Review, Secondary Data Collection

職務経験

Senior Consultant

Sigillum Knowledge Solutions

12月 2018 - 7月 2019

Scientific Advisor

Universidade de Santiago de Compostela

6月 2017 - 11月 2018

NHMRC Postdoctoral Research Officer

University of Adelaide

1月 2015 - 3月 2017

Chemist

Peakdale Molecular Ltd

7月 2014 - 12月 2014

学歴

Clinical Trials Management

Parexel Academy

10月 2019 - 4月 2020

Regulatory Affairs

CESIF

4月 2017 - 12月 2017

PhD in medicinal chemistry (Organic Chemistry)

Universidade de Santiago de Compostela

10月 2008 - 11月 2013

Master in Advanced Chemistry

Universidade de Santiago de Compostela

9月 2009 - 6月 2010

Graduate in Organic Chemistry

Universidad de Santiago de Compostela

10月 2003 - 9月 2008

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Andrew J. Hayes, Jiulia Satiaputra, Louise M. Sternicki, Ashleigh S. Paparella, Zikai Feng, Kwang J. Lee, Beatriz Blanco-Rodriguez, William Tieu, Bart A. Eijkelkamp, Keith E. Shearwin, et al.(2020). Advanced Resistance Studies Identify Two Discrete Mechanisms in Staphylococcus aureus to Overcome Antibacterial Compounds that Target Biotin Protein Ligase . Antibiotics. 9. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 165. {MDPI} {AG}

Andrew J. Hayes, Jiulia Satiaputra, Louise Sternicki, Ashleigh S. Paparella, Zikai Feng, Kwang J. Lee, Beatriz Blanco-Rodriguez, William Tieu, Bart Eijkelkamp, Keith Shearwin, et al. (2020). Advanced Resistance Studies Identify Two Discrete Mechanisms in <i>Staphylococcus aureus</i> to Overcome Antibacterial Compounds that Target Biotin Protein Ligase . Antibiotics.

Marina Pernas, Beatriz Blanco, Emilio Lence, Paul Thompson, Alastair R. Hawkins, Concepci&#243;n Gonz&#225;lez-Bello(2019). Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme . Organic Chemistry Frontiers. 6. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2514--2528. Royal Society of Chemistry ({RSC})

(2019). Synthesis of Rigidified Shikimic Acid Derivatives by Ring-Closing Metathesis to Imprint Inhibitor Efficacy against Shikimate Kinase Enzyme . Organic Chemistry Frontiers.

(2018). A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase . Tetrahedron.

(2017). Azobenzene-containing photoswitchable proteasome inhibitors with selective activity and cellular toxicity . Bioorganic & Medicinal Chemistry.

(2017). Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study . ChemMedChem.

Antonio Pe&#243;n, Adri&#225;n Robles, Beatriz Blanco, Marino Convertino, Paul Thompson, Alastair R. Hawkins, Amedeo Caflisch, Concepci&#243;n Gonz&#225;lez-Bello(2017). Reducing the Flexibility of Type{\hspace{0.25em}}{II} Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study . {ChemMedChem}. 12. (18). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1512--1524. Wiley

(2017). Structure–Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics . Journal of Medicinal Chemistry.

Blanco B, Sedes A, Peón A, Otero JM, van Raaij MJ, Thompson P, Hawkins AR, González-Bello C, Journal of medicinal chemistry, 2014, vol. 57, no. 8, pp. 3494-3510, 2014 .

Seki H, Pellett S, Silhár P, Stowe GN, Blanco B, Lardy MA, Johnson EA, Janda KD, Bioorganic & medicinal chemistry, 2014, vol. 22, no. 3, pp. 1208-1217, 2014 .

Blanco B, Prado V, Lence E, Otero JM, Garcia-Doval C, van Raaij MJ, Llamas-Saiz AL, Lamb H, Hawkins AR, González-Bello C, Journal of the American Chemical Society, 2013, vol. 135, no. 33, pp. 12366-12376, 2013 .

Blanco B, Sedes A, Peón A, Lamb H, Hawkins AR, Castedo L, González-Bello C, Organic & biomolecular chemistry, 2012, vol. 10, no. 18, pp. 3662-3676, 2012 .

CONFERENCE PAPER

(2010). Enol mimics with a flexible side chain as inhibitors of Mycobacterium tuberculosis dehydroquinase. Drugs of the Future (Supplement A).

PATENT

GONZALEZ BELLO CONCEPCION, SANCHEZ SIXTO CRISTINA, SEDES DIAZ ANTIA, BLANCO RODRIGUEZ BEATRIZ, 2010 .