プロフィール詳細

プロジェクトを作成

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Dr. Bethany B.に依頼

United Kingdom

Translational Cancer Immunology Biologist | 3D Tumour Models, Immunotherapy & Preclinical Model Development

プロフィール概要

I am a postdoctoral cancer researcher with expertise in tumour–immune interactions, extracellular matrix (ECM) biology, and translational oncology. My work focuses on how mechanical cues within the tumour microenvironment regulate immune modulation, invasion, and therapy resistance. I have extensive experience in developing and characterising advanced 3D culture systems, including patient-derived organoids, immune co-cultures, and humanised mouse models, as well as profiling transcriptional and secretory responses using NanoString, ELISA, and flow cytometry. With a strong background in experimental design, data analysis, and cross-sector collaboration (academic–industry partnerships, including AstraZeneca), I provide scientific consultancy in cancer immunology, model development, and data interpretation to support translational and preclinical research projects.

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Gene Expression Analysis
• ☆ RNA Sequencing
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Culture
• ☆ 3D Cell Culture
• ☆ Immunohistochemistry
• ☆ Cytometry

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting

Research Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Data Visualization, Data Insights

Product Development Product Validation, Concept Development

職務経験

Postdoctoral Research Associate

King's College London

10月 2022 - 現在

Research Assistant

University of Cambridge

11月 2017 - 10月 2022

Admissions Assistant

King's College London

10月 2017 - 12月 2017

学歴

PhD

UNIVERSITY OF CAMBRIDGE

1月 2019 - 2月 2023

MSc Neuroscience in Neurodegeneration (Institute of Psychiatry, Psychology and Neuroscience)

King's College London

9月 2015 - 9月 2016

BSc With Honours: Psychology (School of Psychology)

University of East Anglia

9月 2012 - 7月 2015

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Bethany Bareham, Matthew Dibble, Maddy Parsons (2024). Defining and modeling dynamic spatial heterogeneity within tumor microenvironments . Current Opinion in Cell Biology.

Bethany Bareham, Nikitas Georgakopoulos, Alba Matas-Céspedes, Michelle Curran, Kourosh Saeb-Parsy(2021). Modeling human tumor-immune environments in vivo for the preclinical assessment of immunotherapies . Cancer Immunology, Immunotherapy. 70. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2737--2750. Springer Science and Business Media {LLC}

Alba Matas-C{\'{e}}spedes and Lee Brown and Krishnaa T Mahbubani and Bethany Bareham and Jackie Higgins and Michelle Curran and Lolke de Haan and Jean-Martin Lapointe and Richard Stebbings and Kourosh Saeb-Parsy(2020). Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome . Clinical & Translational Immunology. 9. (11). Wiley

(2020). Extensive heterogeneity in somatic mutation and selection in the human bladder . Science.

(2020). Distinct microbial and immune niches of the human colon . Nature Immunology.

(2020). Recent Advancements and Applications of Human Immune System Mice in Preclinical Immuno-Oncology . Toxicologic Pathology.

DISSERTATION THESIS

Bethany Bareham (2022). Modelling pancreatic cancer in vivo with patient derived organoids & humanised mouse models for the investigation of immunotherapeutic treatment response .