プロフィール詳細

プロジェクトを作成

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Dr. Cleber C.に依頼

United States

Cheminformatician working on scientific writing, Computer-Aided Drug Design, and machine learning.

プロフィール概要

Ph.D. in Tropical Medicine and Public Health with a Master’s degree in Pharmaceutical Sciences and a Bachelor’s degree in Pharmacy. Postdoctoral Research Associate at the University of North Carolina at Chapel Hill from June/2019 to March/2022. I have experience with scientific writing, Computer-Aided Drug Design (Ligand- and Structure-Based methods), Molecular Modeling, Cheminformatics, and Machine Learning/predictive modeling projects applied to early drug discovery.

専門分野

• ★ Chemoinformatics
• ★ Predictive Modeling & Analytics
• ★ Data Cleaning
• ☆ Data Visualization
• ☆ Data Manipulation

サービス

• Writing
• Research
• Data & AI

Writing Technical Writing

Research Market Research, Gap Analysis, Systematic Literature Review

Data & AI Predictive Modeling, Statistical Analysis, Data Visualization, Big Data Analytics, Data Mining, Data Cleaning, Data Processing

職務経験

Postdoctoral Research Associate

University of North Carolina at Chapel Hill

6月 2019 - 現在

Research Scientist

InsiChem

3月 2017 - 6月 2018

学歴

PhD in Tropical Medicine and Public Health (Tropical Medicine and Public Health Institute)

Universidade Federal de Goiás

3月 2014 - 4月 2018

Master's degree (Faculdade de Farmácia)

Universidade Federal de Goiás

3月 2012 - 3月 2014

Bachelor of Pharmacy (Faculdade de Farmácia)

Universidade Federal de Goiás

3月 2007 - 12月 2011

認定資格

• 認定資格の詳細は未入力です。

出版物

OTHER

Cleber C. Melo-Filho, Tesia Bobrowski, Vinicius Alves, Daniel Korn, Scott S. Auerbach, Charles Schmitt, Eugene Muratov, Alexander Tropsha (2020). Computational Models Identify Several FDA Approved or Experimental Drugs as Putative Agents Against SARS-CoV-2 .

Cleber C. Melo-Filho, Tesia Bobrowski, Vinicius Alves, Daniel Korn, Scott S. Auerbach, Charles Schmitt, Eugene Muratov, Alexander Tropsha(2020). Computational Models Identify Several FDA Approved or Experimental Drugs as Putative Agents Against SARS-CoV-2 . American Chemical Society ({ACS})

JOURNAL ARTICLE

Bobrowski, T., Melo-Filho, C.C., Korn, D., Alves, V.M., Popov, K.I., Auerbach, S., Schmitt, C., Moorman, N.J., Muratov, E.N., Tropsha, A.(2020). Learning from history: do not flatten the curve of antiviral research! . Drug Discovery Today.

Alves, V.M., Bobrowski, T., Melo-Filho, C.C., Korn, D., Auerbach, S., Schmitt, C., Muratov, E.N., Tropsha, A.(2020). QSAR Modeling of SARS-CoV M^pro Inhibitors Identifies Sufugolix, Cenicriviroc, Proglumetacin, and Other Drugs as Candidates for Repurposing against SARS-CoV-2 . Molecular Informatics.

Cleber C. Melo-Filho, Rodolpho C. Braga, Eugene N. Muratov, Caio Haddad Franco, Carolina B. Moraes, Lucio H. Freitas-Junior, Carolina Horta Andrade(2019). Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening . European Journal of Medicinal Chemistry. 163. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 649--659. Elsevier {BV}

Melo-Filho, C.C., Braga, R.C., Muratov, E.N., Franco, C.H., Moraes, C.B., Freitas-Junior, L.H., Andrade, C.H.(2019). Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening . European Journal of Medicinal Chemistry. 163. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 649-659.

Andrade, C.H., Neves, B.J., Melo-Filho, C.C., Rodrigues, J., Silva, D.C., Braga, R.C., Cravo, P.V.L.(2019). In silico chemogenomics drug repositioning strategies for neglected tropical diseases . Current Medicinal Chemistry. 26. (23). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4355-4379.

Melina Mottin, Joyce Villa Verde Bastos Borba, Cleber Camilo Melo-Filho, Bruno Junior Neves, Eugene Muratov, Pedro Henrique Monteiro Torres, Rodolpho Campos Braga, Alexander Perryman, Sean Ekins, Carolina Horta Andrade(2018). Computational drug discovery for the Zika virus . Brazilian Journal of Pharmaceutical Sciences. 54. (spe). {FapUNIFESP} ({SciELO})

Cleber C. Melo-Filho, Bruno J. Neves, Rodolpho C. Braga, José Teófilo Moreira-Filho, Eugene N. Muratov, Carolina Horta Andrade(2018). QSAR-Based Virtual Screening: Advances and Applications in Drug Discovery . Frontiers in Pharmacology. 9. Frontiers Media {SA}

Silva LC, Neves BJ, Gomes MN, Melo-Filho CC, Soares CM, Andrade CH, Pereira M(2018). Computer-aided identification of novel anti-paracoccidioidomycosis compounds . Future microbiology.

Daiane Dias Ferreira, Juliana Tonini Mesquita, Thais Alves da Costa Silva, Maiara Maria Romanelli, Denise da Gama Jaen Batista, Cristiane França da Silva, Aline Nefertiti Silva da Gama, Bruno Junior Neves, Cleber Camilo Melo-Filho, Maria de Nazare Correia Soeiro, et al.(2018). Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study . Journal of Venomous Animals and Toxins including Tropical Diseases. 24. (1). Springer Nature America, Inc

Carolina Horta Andrade, Bruno Junior Neves, Cleber Camilo Melo-Filho, Juliana Rodrigues, Diego Cabral Silva, Rodolpho Campos Braga, Pedro Vitor Lemos Cravo(2018). In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases . Current Medicinal Chemistry. 25. Bentham Science Publishers Ltd.

Cleber C. Melo-Filho, Marilia N. N. Lima, Gustavo C. Cassiano, Bruno J. Neves, Vinicius M. Alves, Rodolpho C. Braga, Pedro V. L. Cravo, Eugene N. Muratov, Juliana Calit, Daniel Y. Bargieri, et al.(2018). QSAR-Driven Design and Discovery of Novel Compounds With Antiplasmodial and Transmission Blocking Activities . Frontiers in Pharmacology. 9. Frontiers Media {SA}

Neves, B.J., Braga, R.C., Melo-Filho, C.C., Moreira-Filho, J.T., Muratov, E.N., Andrade, C.H.(2018). QSAR-based virtual screening: Advances and applications in drug discovery . Frontiers in Pharmacology. 9. (NOV).

Lima, M.N.N., Melo-Filho, C.C., Cassiano, G.C., Neves, B.J., Alves, V.M., Braga, R.C., Cravo, P.V., Muratov, E.N., Calit, J., Bargieri, D.Y., et al.(2018). QSAR-driven design and discovery of novel compounds with antiplasmodial and transmission blocking activities . Frontiers in Pharmacology. 9. (MAR).

Ferreira, D.D., Mesquita, J.T., Da Costa Silva, T.A., Romanelli, M.M., Da Gama Jaen Batista, D., Da Silva, C.F., Da Gama, A.N.S., Neves, B.J., Melo-Filho, C.C., Correia Soeiro, M.D.N., et al.(2018). Efficacy of sertraline against Trypanosoma cruzi: An in vitro and in silico study . Journal of Venomous Animals and Toxins Including Tropical Diseases. 24. (1).

Silva, L.C., Neves, B.J., Gomes, M.N., Melo-Filho, C.C., Soares, C.M.A., Andrade, C.H., Pereira, M.(2018). Computer-aided identification of novel anti-paracoccidioidomycosis compounds . Future Microbiology. 13. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1523-1535.

Mottin, M., Borba, J.V.V.B., Melo-Filho, C.C., Neves, B.J., Muratov, E., Torres, P.H.M., Braga, R.C., Perryman, A., Ekins, S., Andrade, C.H.(2018). Computational drug discovery for the Zika virus . Brazilian Journal of Pharmaceutical Sciences. 54. (Special Issue).

Gomes, M.N., Alcântara, L.M., Neves, B.J., Melo-Filho, C.C., Freitas-Junior, L.H., Moraes, C.B., Ma, R., Franzblau, S.G., Muratov, E., Andrade, C.H.(2017). Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum . Bioorganic and Medicinal Chemistry Letters. 27. (11).

Neves, B.J., Dantas, R.F., Senger, M.R., Melo-Filho, C.C., Valente, W.C.G., De Almeida, A.C.M., Rezende-Neto, J.M., Lima, E.F.C., Paveley, R., Furnham, N., et al.(2016). Discovery of New Anti-Schistosomal Hits by Integration of QSAR-Based Virtual Screening and High Content Screening . Journal of Medicinal Chemistry. 59. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7075-7088.

Melo-Filho, C.C., Dantas, R.F., Braga, R.C., Neves, B.J., Senger, M.R., Valente, W.C.G., Rezende-Neto, J.M., Chaves, W.T., Muratov, E.N., Paveley, R.A., et al.(2016). QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni . Journal of Chemical Information and Modeling. 56. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1357-1372.

Melo-Filho, C.C., Braga, R.C., Andrade, C.H.(2014). 3D-QSAR Approaches in Drug Design: Perspectives to Generate Reliable CoMFA Models . Current Computer-Aided Drug Design. 10. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 148-159.

Melo-Filho, C.C., Braga, R.C., Andrade, C.H.(2014). Advances in methods for predicting phase i metabolism of polyphenols . Current Drug Metabolism. 15. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 120-126.