プロフィール詳細

プロジェクトを作成

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Dr. Darsha P.に依頼

South Korea

PhD Bioinformatics Scientist | Microbiome, Metagenomics, Single-Cell & Multi-omics Analysis

プロフィール概要

I am a PhD-level Bioinformatics Scientist specializing in microbiome research, genome-resolved metagenomics, single-cell genomics, and integrative multi-omics analysis. My work focuses on understanding complex microbial communities in environmental and engineered systems, with particular expertise in anaerobic digestion, biogas production, and biopolymer degradation. During my doctoral and postdoctoral research at Hanyang University, I have developed and applied end-to-end bioinformatics workflows for large-scale omics datasets, including metagenomics, metatranscriptomics, and metabolomics. I have extensive experience in genome-resolved analysis, including assembly, binning, and refinement of metagenome-assembled genomes (MAGs), followed by taxonomic classification and functional annotation using tools such as MEGAHIT, MetaBAT2, CheckM, GTDB-Tk, DRAM, and dbCAN. My expertise extends to integrating multi-omics datasets to uncover metabolic pathways, microbial interactions, and system-level functionality. I have worked on constructing genome-scale metabolic models (GEMs) and community interaction models (e.g., SMETANA), enabling predictive insights into microbial ecosystems. I am also experienced in analyzing CAZyme profiles, plastizyme distribution, and functional enzyme systems relevant to hydrolysis, acidogenesis, acetogenesis, and methanogenesis. In addition, I have strong experience in data visualization and interpretation, generating publication-quality figures including heatmaps, co-occurrence networks, Sankey diagrams, and pathway maps using R and Python. I am comfortable working in Linux-based environments, high-performance computing systems, and reproducible workflows. My research contributions include metagenomic analyses of multiple full-scale biogas plants, identification of key microbial consortia driving methane production, and integration of omics data to improve biomethane yield. I have also worked on microbial systems involved in biodegradable plastic degradation and environmental microbiome dynamics. I am particularly interested in collaborating on projects involving microbiome data analysis, metagenomics and single-cell genomics, multi-omics integration, and environmental or industrial biotechnology applications. I provide clear, reproducible, and publication-ready results, and I am experienced in working with interdisciplinary teams. I am available for both short-term analytical tasks and long-term collaborative research projects.

専門分野

• ☆ Computational Biology
• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Industrial Microbiology
• ☆ Agricultural Microbiology
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Omics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Lipidomics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ PCR
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ Cell Biology
• ☆ Biotechnology & Bioengineering
• ☆ Microbial Biotechnology
• ☆ Biological Systems Engineering
• ☆ Biomass & Bioenergy
• ☆ Data Analysis
• ☆ Machine Learning
• ☆ Environmental Science
• ☆ Environmental Biotechnology
• ☆ Environmental Management & Protection
• ☆ Environmental Policy
• ☆ Environmental Remediation
• ☆ Environmental Health
• ☆ Ecology
• ☆ Conservation Genetics
• ☆ Cell Culture
• ☆ Industrial Biotechnology
• ☆ Bioenergy & Biofuels
• ☆ Microbial Fermentation
• ☆ Agricultural Biotechnology
• ☆ Phylogenetics
• ☆ R
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Survey Design & Methodology
• ☆ Meta-Research
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Language Translation

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing

Research Meta-Research, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Analysis, Data Visualization, Big Data Analytics

Product Development Formulation

職務経験

Hanyang University

- 現在

PostdoctoralResearcher

Hanyang University

3月 2026 - 現在

学歴

Doctor of Philosophy (Ph.D)

Hanyang University

9月 2021 - 2月 2026

Masters in Chemical Engineering

Hanyang University

3月 2019 - 2月 2021

B.Tech. Biotechnology

Anna University

8月 2014 - 4月 2018

認定資格

• Data Science and Machine Learning

  Massachusetts Institute of Technology

  10月 2023 - 現在

• Next-Generation Sequencing (NGS) Workshop

  Galaxy platforms

  1月 2023 - 現在

出版物

JOURNAL ARTICLE

Darsha Prabhaharan, Young Wook Go, Hyunjin Kim, Seongcheol Kang, Byoung-In Sang (2025). Representative Metagenomes of Mesophilic Biogas Reactor Across South Korea . Scientific Data.

Darsha Prabhaharan, Hyojung Park, Okkyoung Choi, Amith Abraham, Byoung-In Sang (2024). Enhancing cellulose acetate biodegradability in cigarette filters: an in-depth analysis of thermal alkaline pretreatment, microbial dynamics, and breakdown pathway prediction . Microbial Cell Factories.

Darsha Prabhaharan, Pranav Sasidharan Nair, Hyojung Park, Okkyoung Choi, Byoung-In Sang, Simon Roux (2024). Complete genome sequence of Methanothermobacter sp. DP, a hydrogenotrophic and thermophilic methanogen . Microbiology Resource Announcements.