プロフィール詳細

プロジェクトを作成

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Dr. Darío F.に依頼

Spain

Expert in molecular biology & biochemistry | PhD | Scientific advisor in biotech, diagnostics & biomedical R&D

プロフィール概要

I am a Molecular Biologist and PhD in Biochemistry with over 10 years of research experience in academia and translational biomedical science. I have led and collaborated on projects involving molecular mechanisms, gene expression, signaling pathways, diagnostics, and personalized medicine. My work has focused on the study of actin and myosin in reproductive biology, tumor cell cycle analysis, and plant-derived bioactive molecules with anticancer properties. I have also developed 3D printed models from medical images for teaching and clinical applications. I have worked at top-level research institutions including CONICET (Argentina), CSIC (Spain), and CIBERER, and I am currently a senior researcher and academic director at the University of Burgos (Spain), where I also lead innovation projects that combine biology, biotechnology, and digital tools. I offer scientific consulting in biotechnology, biomedical R&D, diagnostic technologies, academic writing, experimental design, and project evaluation. I am also a reviewer and member of ethics and research committees, with strong communication skills and a commitment to bridging science and industry.

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ PCR
• ☆ Molecular Cloning
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Mutagenesis
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ Kinases
• ☆ Monoclonal Antibody Production
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cytogenetics
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Cytometry
• ☆ Cell Aging
• ☆ Device Fabrication
• ☆ 3D Printing/Additive Manufacturing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing General Proofreading & Editing, Translation

Research User Research, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting, Regulatory Consulting

Data & AI Statistical Analysis, Image Processing, Image Analysis, Data Visualization

Product Development Recipe Development, Product Evaluation, Prototyping, Device Fabrication

職務経験

Chairman of the Editorial Board

Universidad de Burgos

3月 2022 - 現在

vice-dean

Universidad de Burgos

7月 2021 - 現在

Senior Distinguished Researcher "Beatriz Galindo"

Universidad de Burgos

2月 2020 - 現在

Scientific Researcher

National Scientific and Technical Research Council

6月 2012 - 1月 2023

Full Professor

National University of the Northeast. School of Dentistry

12月 2017 - 1月 2020

Researcher

National Scientific and Technical Research Council

6月 2012 - 11月 2017

Posdoctoral Fellow

National Scientific and Technical Research Council

3月 2012 - 5月 2012

Researcher

Centre for Biomedical Network Research on Rare Diseases

9月 2009 - 12月 2011

PhD student

Spanish National Research Council

9月 2004 - 8月 2009

PhD student

National Scientific and Technical Research Council

3月 2001 - 8月 2004

学歴

PhD. Biochemistry and Molecular Biology (Department of Biochemistry and Molecular Biology)

Complutense University of Madrid

9月 2006 - 6月 2011

PhD. Biochemistry (School of Chemistry Biochemistry and Pharmacy)

National University of San Luis

3月 2004 - 11月 2008

MSc. Biochemistry and Molecular Biology (Department of Biochemistry and Molecular Biology)

Complutense University of Madrid

9月 2006 - 6月 2008

Degree in Molecular Biology (School of Chemistry Biochemistry and Pharmacy)

National University of San Luis

3月 1996 - 12月 2003

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Malena Pérez-Sevilla, Fernando Rivas-Navazo, Pedro Latorre-Carmona, Darío Fernández-Zoppino (2025). Protocol for Converting DICOM Files to STL Models Using 3D Slicer and Ultimaker Cura . Journal of Personalized Medicine.

Malena Pérez Sevilla, Fernando Rivas Navazo, Pedro Latorre Carmona, Fernández, D; Fernández Zoppino, D (2025). Protocol for Converting DICOM Files to STL Models Using 3D Slicer and Ultimaker Cura . Journal of Personalized Medicine.

Carla Hernando-Muñoz, Andrea Revilla-Cuesta, Irene Abajo-Cuadrado, Camilla Andreini, Tomás Torroba, Natalia Busto, Darío Fernández, German Perdomo, Gerardo Acosta, Miriam Royo, et al. (2025). Self-assembling Depsipeptides on Aggregation-Induced Emission Luminogens: A New Way to Create Programmable Nanovesicles and Soft Nanocarriers . ACS Applied Materials & Interfaces.

Abi K. Funes, Virginia Avena, Paola V. Boarelli, María A. Monclus, Dario Fernández Zoppino, T Estefanía Saez Lancellotti, Miguel Fornés (2024). Cholesterol dynamics in rabbit liver: High-fat diet, olive oil, and synergistic dietary effects . Biochemical and Biophysical Research Communications.

Natalia Fern{\'{a}}ndez-Pamp{\'{\i}}n and M{\'{o}}nica Vaquero and Tania Gil and Gustavo Espino and Dar{\'{\i}}o Fern{\'{a}}ndez and Bego{\~{n}}a Garc{\'{\i}}a and Natalia Busto(2022). Distinct mechanism of action for antitumoral neutral cyclometalated Pt(II)-complexes bearing antifungal imidazolyl-based drugs . Journal of Inorganic Biochemistry. 226. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 111663. Elsevier {BV}

Frank Lizaraso-Soto and Eduardo Guti{\'{e}}rrez-Abej{\'{o}}n and Juan Bustamante-Munguira and D{\'{e}}bora Mart{\'{\i}}n-Garc{\'{\i}}a and Mar{\'{\i}}a Montserrat Chimeno and {\'{A}}lvaro Nava-Rebollo and {\'{A}}lvaro Maurtua-Brise{\~{n}}o-Meiggs and Dar{\'{\i}}o Fern{\'{a}}ndez-Zoppino and Elena Bustamante-Munguira and F{\'{e}}lix Jes{\'{u}}s de Paz and Jes{\'{u}}s Grande-Villoria and Carlos Ochoa-Sangrador and Manuel Pascual and F. Javier {\'{A}}lvarez and Francisco Herrera-G{\'{o}}mez(2021). Binding Potassium to Improve Treatment With Renin-Angiotensin-Aldosterone System Inhibitors: Results From Multiple One-Stage Pairwise and Network Meta-Analyses of Clinical Trials . Frontiers in Medicine. 8. Frontiers Media {SA}

Ana Merino-Merino, Jeronimo Gonzalez-Bernal, Dario Fernandez-Zoppino, Ruth Saez-Maleta, Jose-Angel Perez-Rivera(2021). The Role of Galectin-3 and ST2 in Cardiology: A Short Review . Biomolecules. 11. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1167. {MDPI} {AG}

Diego Fern{\'{a}}ndez-L{\'{a}}zaro and David Gallego-Gallego and Luis A. Corchete and Dar{\'{\i}}o Fern{\'{a}}ndez Zoppino and Jer{\'{o}}nimo J. Gonz{\'{a}}lez-Bernal and Blanca Garc{\'{\i}}a G{\'{o}}mez and Juan Mielgo-Ayuso(2021). Inspiratory Muscle Training Program Using the PowerBreath®: Does It Have Ergogenic Potential for Respiratory and/or Athletic Performance? A Systematic Review with Meta-Analysis . International Journal of Environmental Research and Public Health. 18. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6703. {MDPI} {AG}

(2021). Athletic, muscular and hormonal evaluation in CrossFit  athletes using the “Elevation Training Mask” . Arch Med Deporte.

JG. Becchio and RO. Rosende and JE. Monz{\'{o}}n and D. Fern{\'{a}}ndez and PB. Said-Rücker(2021). Ultrasonic techniques to obtain dental pulp from impacted third molars . Journal of Clinical and Experimental Dentistry. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e1--e7. Medicina Oral, S.L.

(2019). Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells . World Journal of Stem Cells.

Said Rücker PB, Rosende RO, Krupp S, Becchio JG, Fernández D (2018) Functional Approaches to Oral-Maxillo-facial Restoration. Dentistry 8: 499. Doi: 10.4172/2161-1122.1000499 .

Costantino, V.V., Lobos-Gonzalez, L., Ibañez, J., Fernandez, D., Cuello-Carrión, F.D., Valenzuela, M.A., Barbieri, M.A., Semino, S.N., Jahn, G.A., Quest, A.F.G., et al.(2016). Dehydroleucodine inhibits tumor growth in a preclinical melanoma model by inducing cell cycle arrest, senescence and apoptosis . Cancer Letters. 372. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 10-23.

Fernández, D., Horrillo, A., Alquezar, C., González-Manchón, C., Parrilla, R., Ayuso, M.S.(2013). Control of cell adhesion and migration by podocalyxin. Implication of Rac1 and Cdc42 . Biochemical and Biophysical Research Communications. 432. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 302-307.

Losinno, A.D., Morales, A., Fernández, D., Lopez, L.A.(2012). Peritubular myoid cells from rat seminiferous tubules contain actin and myosin filaments distributed in two independent layers . Biology of Reproduction. 86. (5).

Pericacho, M., Alonso-Martín, S., Larrucea, S., González-Manchón, C., Fernández, D., Sánchez, I., Ayuso, M.S., Parrilla, R.(2011). Diminished thrombogenic responses by deletion of the Podocalyxin gene in mouse megakaryocytes . PLoS ONE. 6. (10).

Nowakowski, A., Alonso-Martín, S., Arias-Salgado, E.G., Fernández, D., Vilar, M., Ayuso, M.S., Parrilla, R.(2011). Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre . Thrombosis and Haemostasis. 105. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 138-144.

Fernández, D., Larrucea, S., Nowakowski, A., Pericacho, M., Parrilla, R., Ayuso, M.S.(2011). Release of podocalyxin into the extracellular space. Role of metalloproteinases . Biochimica et Biophysica Acta - Molecular Cell Research. 1813. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1504-1510.

Alonso-Martin, S., Nowakowski, A., Larrucea, S., Fernández, D., Vilar-Egea, M., Ayuso, M.S., Parrilla, R.(2010). Overexpression of podocalyxin in megakaryocytes and platelets decreases the bleeding time and enhances the agonist-induced aggregation of platelets . Thrombosis Research. 125. (6).

Nowakowski, A., Alonso-Martín, S., González-Manchón, C., Larrucea, S., Fernández, D., Vilar, M., Cerdán, S., Ayuso, M.S., Parrilla, R.(2010). Ventricular enlargement associated with the panneural ablation of the podocalyxin gene . Molecular and Cellular Neuroscience. 43. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 90-97.

Fernández, D., Bertoldi, M.V., Gómez, L., Morales, A., Callegari, E., Lopez, L.A.(2008). Identification and characterization of myosin from rat testicular peritubular myoid cells . Biology of Reproduction. 79. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1210-1218.

Arias-Salgado, E.G., Larrucea, S., Butta, N., Fernández, D., García-Muñoz, S., Parrilla, R., Ayuso, M.S.(2008). Variations in platelet protein associated with arterial thrombosis . Thrombosis Research. 122. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 640-647.

Cruzado M, Castro C, Fernandez D, Gomez L, Roque M, Giordano OE, Lopez LA(2005). Dehydroleucodine inhibits vascular smooth muscle cell proliferation in G2 phase . Cellular and molecular biology (Noisy-le-Grand, France).

Cruzado, M., Castro, C., Fernández, D., Gomez, L., Roqué, M., Giordano, O.E., Lopez, L.A.(2005). Dehydroleucodine inhibits vascular smooth muscle cell proliferation in G2 phase . Cellular and Molecular Biology. 51. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 525-530.

Gamarra-Luques, C., Polo, M., Fernández, D., Arenas, G.N., Salomón, C.(2003). Effect of the coinfection with Escherichia coli on Leishmania sp phagocytosis in macrophage,Efecto de la coinfeccíon con E. coli sobre la fagocitosis de Leishmanias sp. en macrófagos . Prensa Medica Argentina. 90. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 248-253.

BOOK

Raúl Horacio Lucero, Darío Fernández Zoppino, Juan Estanislao Camarasa (2025). Cronista de una larga y silenciosa tragedia argentina .

PREPRINT

Peritubular macrophages phagocyte remains of undifferentiated spermatogonia in mouse testis <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> .

DISSERTATION THESIS

Fern\'andez, Dar\'\\io(2011). Caracterización, localización celular e interacción con otras proteínas de la podocalicina humana expresada en sistemas heterólogos.

Fern\'andez, Dar\'\\io(2008). Características de contracción de células mioides peritubulares del túbulo seminifero de testículo de rata.