プロフィール詳細

プロジェクトを作成

★★★★★

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★★★★★

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Dr. Damien T.に依頼

France

Freelance scientific expert specialized in preclinical development - technical writer

プロフィール概要

Scientist executive (PhD) and entrepreneur with extensive experience in biotech R&D. Deep technical and scientific expertise (15+ years) in neurodegenerative disorders (Parkinson’s disease, ALS, Alzheimer’s disease) with strong business and project management insights. Drug hunter with passion for building and translating projects from early exploratory up to clinical candidate validation. technical writer with demonstrated ability tosuccesfully publish articles and obtain grants

専門分野

• ★ Drug Discovery
• ★ Preclinical Research
• ★ Grant Writing
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Drug Design
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Biosafety Testing
• ☆ Microbiology Testing
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Drug Efficacy Testing
• ☆ Bioavailability
• ☆ Pharmaceutical Manufacturing
• ☆ Pharmaceutical Process Development
• ☆ Biologic & Biosimilar Manufacturing
• ☆ Immunotherapy
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Regulatory Writing
• ☆ CMC Documentation
• ☆ Nonclinical Study Documentation
• ☆ Medical Writing
• ☆ Medical Content Writing
• ☆ Healthcare Communications
• ☆ Research Summaries & Abstracts
• ☆ Investigational New Drug (IND) Application Writing
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Release Notes
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Spec Sheets
• ☆ Case Studies
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Language Translation
• ☆ Screenwriting
• ☆ Creative Writing
• ☆ Audio Transcription
• ☆ Speechwriting
• ☆ News Writing
• ☆ Course Content Writing

サービス

• Writing

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Business & Legal Writing, Copywriting, Newswriting, Audio Transcription, General Proofreading & Editing, Translation

職務経験

Chief Scientific Officer

ENCEFA

9月 2015 - 現在

Founder/CSO

ENCEFA

10月 2015 - 10月 2023

Chief Project Manager

Pharnext

3月 2014 - 9月 2015

Project manager

Pharnext

3月 2014 - 9月 2015

Sientific consultant

Subventium

1月 2011 - 7月 2013

学歴

Université Pierre et Marie Curie

9月 2007 - 12月 2010

PhD

Université Pierre et Marie Curie (Paris VI) - France

1月 2007 - 12月 2010

M.Sc Biochemistry and Genetics

AGROCAMPUS OUEST

9月 2004 - 6月 2007

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Damien Toulorge, Serge Guerreiro, Anne-Laure Privat, Laurence Bressac(2020). CD38 in Neurodegeneration and Neuroinflammation . Cells. 9. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 471. {MDPI} {AG}

Damien Toulorge and Anthony H. V. Schapira and Rodolphe Hajj(2016). Molecular changes in the postmortem parkinsonian brain . Journal of Neurochemistry. 139. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 27--58. Wiley

Rodolphe Hajj and Aude Milet and Damien Toulorge and Nathalie Cholet and Julien Laffaire and Julie Foucquier and Sandra Robelet and Richard Mitry and Mickael Guedj and Serguei Nabirotchkin and Ilya Chumakov and Daniel Cohen(2015). Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease . Scientific Reports. 5. (1). Springer Science and Business Media {LLC}

Ilya Chumakov and Serguei Nabirotchkin and Nathalie Cholet and Aude Milet and Aur{\'{e}}lie Boucard and Damien Toulorge and Yannick Pereira and Esther Graudens and Sory Traor{\'{e}} and Julie Foucquier and Mickael Guedj and Emmanuel Vial and Noëlle Callizot and R{\'{e}}my Steinschneider and Tangui Maurice and Viviane Bertrand and Catherine Scart-Gr{\`{e}}s and Rodolphe Hajj and Daniel Cohen(2015). Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy . Scientific Reports. 5. (1). Springer Science and Business Media {LLC}

Patrick P. Michel and Damien Toulorge and Serge Guerreiro and Etienne C. Hirsch(2013). Specific needs of dopamine neurons for stimulation in order to survive: implication for Parkinson disease . The FASEB Journal. 27. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3414--3423. Wiley

Damien Toulorge and Serge Guerreiro and Audrey Hild and Uwe Maskos and Etienne C. Hirsch and Patrick P. Michel(2011). Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca 2+ . The FASEB Journal. 25. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2563--2573. Wiley

Damien Toulorge and Serge Guerreiro and Etienne C. Hirsch and Patrick P. Michel(2010). KATP channel blockade protects midbrain dopamine neurons by repressing a glia-to-neuron signaling cascade that ultimately disrupts mitochondrial calcium homeostasis . Journal of Neurochemistry. 114. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 553--564. Wiley

Serge Guerreiro and Aur{\'{e}}lie Ponceau and Damien Toulorge and Elodie Martin and Daniel Alvarez-Fischer and Etienne C. Hirsch and Patrick P. Michel(2009). Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization . Journal of Neurochemistry. 109. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1118--1128. Wiley

Serge Guerreiro and Damien Toulorge and Etienne Hirsch and Marc Marien and Pierre Sokoloff and Patrick P. Michel(2008). Paraxanthine, the Primary Metabolite of Caffeine, Provides Protection against Dopaminergic Cell Death via Stimulation of Ryanodine Receptor Channels . Molecular Pharmacology. 74. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 980--989. American Society for Pharmacology {\&} Experimental Therapeutics ({ASPET})