プロフィール詳細

プロジェクトを作成

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Dr. Daniel G.に依頼

United States

Biomedical Scientist with 15 years of experience in the life science sector | Expert technical communicator

プロフィール概要

I'm a versatile biomedical scientist with 7 years of industry experience leading preclinical projects focused on advancing gene therapy candidates from early discovery to IND-enabling development. With over a decade of wet lab research experience, I have expertise in RNA therapeutics design and delivery, therapeutic gene editing platforms, therapeutic protein engineering, and pharmacology studies in mice and non-human primates. I'm passionate about moving projects forward with a collaborative approach and multi-team coordination. I'm a proven effective communicator across diverse audiences including upper management, senior leadership, and boards of directors. I'm also adept at technical writing and communication as a published author in several high-impact peer reviewed journals.

専門分野

• ☆ Molecular Biology
• ☆ Genetics
• ☆ PCR
• ☆ Next Generation Sequencing (NGS)
• ☆ Gene Expression Analysis
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Histology
• ☆ Biotechnology & Bioengineering
• ☆ Biomedical Engineering
• ☆ Microscopy
• ☆ Fluorescence Microscopy
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Line Engineering
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Biomolecular Engineering
• ☆ Gene Editing/CRISPR
• ☆ Gene Delivery
• ☆ Blotting
• ☆ Cytometry
• ☆ Soccer
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Drug Design
• ☆ Drug Development
• ☆ Drug Substance Characterization
• ☆ Microbiology Testing
• ☆ Bioanalytical Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Rare Diseases
• ☆ Amyloidosis
• ☆ Gene Therapy
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Drug Delivery Technologies
• ☆ Liposomes
• ☆ Medical Writing
• ☆ Research Summaries & Abstracts

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Medical Writing, Technical Writing, General Proofreading & Editing

Research Feasibility Study, Technology Scouting, Fact Checking, Gap Analysis

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Analysis, Data Visualization, Data Processing

職務経験

Scientist II

Arcturus Therapeutics (United States)

6月 2021 - 現在

Post-doctoral Fellow

Ionis Pharmaceuticals (United States)

7月 2018 - 5月 2021

学歴

PhD (Biomedical Sciences)

University of California, San Diego

8月 2012 - 7月 2018

BS (Biology)

Harvey Mudd College

2006 - 2010

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Daniel A. Garcia, Abigail F. Pierre, Linda Quirino, Grishma Acharya, Aishwarya Vasudevan, Yihua Pei, Emily Chung, Jason Y.H. Chang, Samuel Lee, Michael Endow, et al. (2025). Lipid nanoparticle delivery of TALEN mRNA targeting LPA causes gene disruption and plasma lipoprotein(a) reduction in transgenic mice . Molecular Therapy.

Daniel A. Garcia, Andrew F. Powers, Thomas A. Bell, 3rd, Shuling Guo, Mariam Aghajan(2022). Antisense Oligonucleotide-Mediated Silencing of Mitochondrial Fusion and Fission Factors Modulates Mitochondrial Dynamics and Rescues Mitochondrial Dysfunction . Nucleic Acid Therapeutics. Mary Ann Liebert Inc

(2018). USP11 Enhances TGFβ-Induced Epithelial-Mesenchymal Plasticity and Human Breast Cancer Metastasis . Molecular cancer research : MCR.

(2017). Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification . The Journal of clinical investigation.

(2016). Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition . Oncotarget.

(2011). Fungal chitin from asthma-associated home environments induces eosinophilic lung infiltration . Journal of immunology (Baltimore, Md. : 1950).