level-one heading

ライター
データアナリスト
コンサルタント
製品開発者
研究者
Kolabtreeを選ぶ理由
開始はすばやく簡単です。初期費用はかかりません。
サービス依頼と専門家への見積依頼は無料です。
Kolabtree の作業範囲に同意する前に、専門家と要件を詳しく相談できます。
専門家と直接連携し、必要な成果を正しく得られます。
専門家を採用したらプロジェクトに資金を入れ、作業完了後に成果物を承認できます。
この専門家をプロジェクトに採用したいですか？ 見積もりを依頼 無料で。
プロフィール詳細
プロジェクトを作成
★★★★★
☆☆☆☆☆
Dr. Deanne S.に依頼
United States

Experience in computational protein, peptide and RNA design and biophysical characterization

プロフィール概要
専門分野
サービス
Writing Technical Writing
Research Technology Scouting, Scientific and Technical Research
Consulting Scientific and Technical Consulting
Data & AI Predictive Modeling, Algorithm Design-Non ML, Data Visualization, Big Data Analytics
Product Development Product Evaluation, Product Validation
職務経験

Senior Principal Scientist

Pfizer

9月 2022 - 10月 2024

Director of Protein Engineering

Molecular Assemblies

5月 2020 - 9月 2022

AI Research Scientist

National Renewable Energy Laboratory

1月 2011 - 8月 2019

学歴

Postdoctoral Research in Chemistry and Biochemistry

University of Colorado, Boulder

8月 2008 - 1月 2011

Biophysics and Biochemistry

University of North Carolina, Chapel Hill

9月 2002 - 8月 2008

認定資格
  • 認定資格の詳細は未入力です。
出版物
JOURNAL ARTICLE
DeChellis, A., Nemmaru, B., Sammond, D., Douglass, J., Patil, N., Reste, O., Chundawat, S.P.S.(2024). Supercharging Carbohydrate Binding Module Alone Enhances Endocellulase Thermostability, Binding, and Activity on Cellulosic Biomass . ACS Sustainable Chemistry and Engineering. 12. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3500-3516.
Chung, D., Sarai, N.S., Knott, B.C., Hengge, N., Russell, J.F., Yarbrough, J.M., Brunecky, R., Young, J., Supekar, N., Vander Wall, T., et al.(2019). Glycosylation Is Vital for Industrial Performance of Hyperactive Cellulases . ACS Sustainable Chemistry and Engineering. 7. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4792-4800.
Sammond, D.W., Kastelowitz, N., Donohoe, B.S., Alahuhta, M., Lunin, V.V., Chung, D., Sarai, N.S., Yin, H., Mittal, A., Himmel, M.E., et al.(2018). An iterative computational design approach to increase the thermal endurance of a mesophilic enzyme . Biotechnology for Biofuels. 11. (1).
Haarmeyer, C.N., Smith, M.D., Chundawat, S.P.S., Sammond, D., Whitehead, T.A.(2017). Insights into cellulase-lignin non-specific binding revealed by computational redesign of the surface of green fluorescent protein . Biotechnology and Bioengineering. 114. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 740-750.
Brunecky, R., Alahuhta, M., Sammond, D.W., Xu, Q., Chen, M., Wilson, D.B., Brady, J.W., Himmel, M.E., Bomble, Y.J., Lunin, V.V.(2017). Natural diversity of glycoside hydrolase family 48 exoglucanases: Insights from structure Mike Himmel . Biotechnology for Biofuels. 10. (1).
Sammond, D.W., Kastelowitz, N., Himmel, M.E., Yin, H., Crowley, M.F., Bomble, Y.J.(2016). Comparing residue clusters from thermophilic and mesophilic enzymes reveals adaptive mechanisms . Plos One. 11. (1).
Qin, Y., Sammond, D.W., Braselmann, E., Carpenter, M.C., Palmer, A.E.(2016). Development of an Optical Zn2+ Probe Based on a Single Fluorescent Protein . ACS Chemical Biology. 11. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2744-2751.
Yarbrough, J.M., Mittal, A., Mansfield, E., Taylor, L.E., Hobdey, S.E., Sammond, D.W., Bomble, Y.J., Crowley, M.F., Decker, S.R., Himmel, M.E., et al.(2015). New perspective on glycoside hydrolase binding to lignin from pretreated corn stover . Biotechnology for Biofuels. 8. (1).
Alahuhta, M., Taylor, L.E., Brunecky, R., Sammond, D.W., Michener, W., Adams, M.W.W., Himmel, M.E., Bomble, Y.J., Lunin, V.(2015). The catalytic mechanism and unique low pH optimum of Caldicellulosiruptor bescii family 3 pectate lyase . Acta Crystallographica Section D Biological Crystallography. 71. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1946-1954.
Sammond, D.W., Yarbrough, J.M., Mansfield, E., Bomble, Y.J., Hobdey, S.E., Decker, S.R., Taylor, L.E., Resch, M.G., Bozell, J.J., Himmel, M.E., et al.(2014). Predicting enzyme adsorption to lignin films by calculating enzyme surface hydrophobicity . Journal of Biological Chemistry. 289. (30). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 20960-20969.
Lee, J., Sammond, D.W., Fiorini, Z., Saludes, J.P., Resch, M.G., Hao, B., Wang, W., Yin, H., Liu, X.(2013). Computationally Designed Peptide Inhibitors of the Ubiquitin E3 Ligase SCFFbx4 . Chembiochem. 14. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 445-451.
Sammond, D.W., Payne, C.M., Brunecky, R., Himmel, M.E., Crowley, M.F., Beckham, G.T.(2012). Cellulase linkers are optimized based on domain type and function: insights from sequence analysis, biophysical measurements, and molecular simulation . Plos One. 7. (11).
Sammond, D.W., Bosch, D.E., Butterfoss, G.L., Purbeck, C., MacHius, M., Siderovski, D.P., Kuhlman, B.(2011). Computational design of the sequence and structure of a protein-binding peptide . Journal of the American Chemical Society. 133. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4190-4192.
Bosch, D.E., Kimple, A.J., Sammond, D.W., Muller, R.E., Miley, M.J., Machius, M., Kuhlman, B., Willard, F.S., Siderovski, D.P.(2011). Structural determinants of affinity enhancement between GoLoco motifs and G-protein α subunit mutants . Journal of Biological Chemistry. 286. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3351-3358.
Sammond, D.W., Joce, C., Takeshita, R., McQuate, S.E., Ghosh, N., Martin, J.M., Yin, H.(2011). Transmembrane peptides used to investigate the homo-oligomeric interface and binding hotspot of latent membrane protein 1 . Biopolymers. 95. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 772-784.
Sammond, D.W., Eletr, Z.M., Purbeck, C., Kuhlman, B.(2010). Computational design of second-site suppressor mutations at protein-protein interfaces . Proteins Structure Function and Bioinformatics. 78. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1055-1065.
Slivka, P.F., Shridhar, M., Lee, G.-I., Sammond, D.W., Hutchinson, M.R., Martinko, A.J., Buchanan, M.M., Sholar, P.W., Kearney, J.J., Harrison, J.A., et al.(2009). A peptide antagonist of the TLR4-MD2 interaction . Chembiochem. 10. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 645-649.
Sammond, D.W., Eletr, Z.M., Purbeck, C., Kimple, R.J., Siderovski, D.P., Kuhlman, B.(2007). Structure-based Protocol for Identifying Mutations that Enhance Protein-Protein Binding Affinities . Journal of Molecular Biology. 371. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1392-1404.
Urbanc, B., Cruz, L., Ding, F., Sammond, D., Khare, S., Buldyrev, S.V., Stanley, H.E., Dokholyan, N.V.(2004). Molecular dynamics simulation of amyloid β dimer formation . Biophysical Journal. 87. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2310-2321.
Jurevics, H., Hostettler, J., Sammond, D.W., Nave, K.-A., Toews, A.D., Morell, P.(2003). Normal metabolism but different physical properties of myelin from mice deficient in proteolipid protein . Journal of Neuroscience Research. 71. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 826-834.
Jurevics, H., Largent, C., Hostettler, J., Sammond, D.W., Matsushima, G.K., Kleindienst, A., Toews, A.D., Morell, P.(2002). Alterations in metabolism and gene expression in brain regions during cuprizone-induced demyelination and remyelination . Journal of Neurochemistry. 82. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 126-136.
Jurevics, H., Hostettler, J., Muse, E.D., Sammond, D.W., Matsushima, G.K., Toews, A.D., Morell, P.(2001). Cerebroside synthesis as a measure of the rate of remyelination following cuprizone-induced demyelination in brain . Journal of Neurochemistry. 77. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1067-1076.
OTHER
DeChellis, A., Nemmaru, B., Sammond, D., Douglass, J., Patil, N., Reste, O., Chundawat, S.P.S.(2023). Supercharging carbohydrate-binding module alone enhances endocellulase thermostability, binding, and activity on cellulosic biomass . Biorxiv.