プロフィール詳細

プロジェクトを作成

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Dr. Derek C.に依頼

Canada

Freelance Scientific Editor | Experienced with Medical Devices, Pharmaceuticals, & in vitro Diagnostics

プロフィール概要

I completed my PhD in Chemical Biology and have previously worked in the medical device, pharmaceutical, and in vitro diagnostics industries.

専門分野

• ★ Drug Target Identification
• ★ Antibiotic Development
• ★ In vitro Diagnostics
• ☆ Microbiology
• ☆ Industrial Microbiology
• ☆ Microbiological Assays
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ Molecular Evolution
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ ATAC-Seq
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Mutagenesis
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ ChIP-Seq
• ☆ Kinases
• ☆ Monoclonal Antibody Production
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Electron Microscopy
• ☆ Fluorescence Microscopy
• ☆ Pathogenesis
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Synthetic Biology
• ☆ Chemical Biology
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Microbiology Testing
• ☆ Bioanalytical Testing
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ In vitro Preclinical Toxciology
• ☆ Medical Devices
• ☆ Post-Market Surveillance
• ☆ Medical Device Development
• ☆ Medical Device Manufacturing
• ☆ Medical Device Validation
• ☆ Medical Implants
• ☆ Medical Device Regulatory Consulting
• ☆ European Medical Device Regulation (MDR)
• ☆ ISO 13485
• ☆ In vitro Diagnostic Validation
• ☆ In vitro Diagnostic Design
• ☆ Point-of-Care Devices
• ☆ Biomarker Analysis
• ☆ Lab-on-a-Chip Devices

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing, Newswriting

Research Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Operations Consulting, Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization, Data Processing

Product Development Stability/Shelf Life Testing, Product Evaluation, Quality Assurance & Control (QA/QC), Product Compliance

職務経験

Project Manager

Funglyn Inc.

8月 2023 - 現在

Doctoral Researcher and Graduate Teaching Assistant

McMaster University

9月 2018 - 8月 2023

Preclinical Drug Discovery Researcher

Apotex Inc.

1月 2017 - 9月 2017

Medical Device Associate

BioIntegral Surgical Inc.

9月 2015 - 9月 2016

学歴

Doctor of Philosophy (Ph.D)

McMaster University

9月 2018 - 8月 2023

Bachelors in Science (Biochemistry)

University of Waterloo

9月 2013 - 4月 2018

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Derek C. K. Chan, Inokentijs Josts, Kalinka Koteva, Gerard D. Wright, Henning Tidow, Lori L. Burrows (2023). Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction . Proceedings of the National Academy of Sciences.

Derek C. K. Chan, Lori L. Burrows, Deborah A. Hogan (2023). Pseudomonas aeruginosa FpvB Is a High-Affinity Transporter for Xenosiderophores Ferrichrome and Ferrioxamine B . mBio.

Derek C K Chan, Lori L Burrows(2021). Thiocillin and micrococcin exploit the ferrioxamine receptor of Pseudomonas aeruginosa for uptake . Journal of Antimicrobial Chemotherapy. Oxford University Press ({OUP})

Luke N. Yaeger, Victoria E. Coles, Derek C. K. Chan, Lori L. Burrows (2021). How to kill Pseudomonas—emerging therapies for a challenging pathogen . Annals of the New York Academy of Sciences.

Derek C. K. Chan and Lori L. Burrows(2021). Thiopeptides: antibiotics with unique chemical structures and diverse biological activities . The Journal of Antibiotics. 74. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 161--175. Springer Science and Business Media {LLC}

Derek C. K. Chan and Lori L. Burrows(2021). Thiopeptides: antibiotics with unique chemical structures and diverse biological activities . The Journal of Antibiotics. 74. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 161--175. Springer Science and Business Media {LLC}

Derek C. K. Chan and Irene Guo and Lori L. Burrows(2020). Forging New Antibiotic Combinations under Iron-Limiting Conditions . Antimicrobial Agents and Chemotherapy. 64. (3). American Society for Microbiology

Michael R. M. Ranieri and Derek C. K. Chan and Luke N. Yaeger and Madeleine Rudolph and Sawyer Karabelas-Pittman and Hamdi Abdo and Jessica Chee and Hanjeong Harvey and Uyen Nguyen and Lori L. Burrows(2019). Thiostrepton Hijacks Pyoverdine Receptors To Inhibit Growth of Pseudomonas aeruginosa . Antimicrobial Agents and Chemotherapy. 63. (9). American Society for Microbiology

PREPRINT

Derek C. K. Chan, Katherine Dykema, Mahrukh Fatima, Hanjeong Harvey, Ikram Qaderi, Lori L. Burrows (2023). Nutrient Limitation SensitizesPseudomonas aeruginosato Vancomycin .

A single extracellular loop of FoxA controls ligand specificity, uptake, and signaling inPseudomonas aeruginosa <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> .