プロフィール詳細

プロジェクトを作成

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Dr. Diana R.に依頼

Portugal

Regulatory Affairs Consultant & Data Analyst | PhD in Biomedicine | Biostatistics & Medical Writing

プロフィール概要

I am a PhD-level biomedical scientist, preclinical data analyst, and regulatory specialist with over 7 years of deep, hands-on experience designing, executing, and analyzing complex in vivo (rodent) research experiments. My expertise lies at the critical bridge between preclinical discovery and clinical translation. I have a proven track record of managing large behavioral, neurochemical, and physiological datasets, taking raw animal trial data, performing biostatistical analysis and data cleaning (using Excel, R and GraphPad Prism), and translating those complex findings into clear, audit-ready documentation. Combined with a specialization in Regulatory Affairs and Technical Direction, I know exactly how to structure data to meet strict regulatory guidelines for upcoming clinical phases. As an independent consultant, I provide specialized support across four core pillars: - Experimental & Protocol Design: Consulting on in vivo experimental design, sample size calculations (power analysis), and ethical/methodological optimization for animal studies. - Preclinical data analysis & Biostatistics: Advanced statistical modeling of in vivo datasets, safety/efficacy data analysis, data cleaning, and high-quality scientific data visualization. - Translational medical writing: Drafting preclinical study reports, and peer-reviewed manuscripts. - Regulatory affairs & Compliance: Navigating early-stage regulatory hurdles, Technical File preparation, and compliance strategies for biotech and life science startups moving from bench to market. Whether you need a specialist to clean and analyze raw animal trial data, structure your non-clinical study reports for a regulatory dossier, or ghostwrite high-tier scientific articles, I deliver the rigorous data oversight your project demands.

専門分野

• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Omics
• ☆ Neuroscience
• ☆ Behavioral Neuroscience
• ☆ Molecular Neuroscience
• ☆ Systems Neuroscience
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Data Analysis
• ☆ Python
• ☆ SPSS
• ☆ Excel
• ☆ R
• ☆ Inflammation
• ☆ Literature Search
• ☆ Gap Analysis
• ☆ Medical Writing
• ☆ Medical Content Writing
• ☆ Research Summaries & Abstracts
• ☆ Cochrane Reviews
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Language Translation
• ☆ Grant Writing

サービス

• Writing

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, General Proofreading & Editing

職務経験

Research Fellow

Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde

10月 2019 - 3月 2026

Visiting Researcher (PhD)

University Medical Center (UMC) Utrecht

6月 2024 - 1月 2025

Final Year Internship

Unit for Multidisciplinary Research in Biomedicine (UMIB)

9月 2016 - 7月 2017

学歴

PhD in Biomedicine and Health Sciences

University of Minho

1月 2022 - 3月 2026

Masters in Health Sciences (School of Medicine)

University of Minho

9月 2017 - 11月 2019

First Degree in Biochemistry (Faculty of Sciences)

University of Porto

9月 2014 - 7月 2017

認定資格

• Specialization in Regulatory Affairs and Technical Direction

  Invictus Sciences

  6月 2026 - 現在

• CONCIOUS II - Curriculum Development of Human Clinical Trials

  European Clinical Research Infrastructure Network

  4月 2024 - 現在

• Certificate of Advanced English

  Cambridge

  10月 2020 - 現在

出版物

JOURNAL ARTICLE

Joana Gonçalves, Diana Fonseca-Rodrigues, Inês Martins Laranjeira, Armando Almeida, Filipa Pinto-Ribeiro (2026). Time-dependent characterisation of sex differences in the chronic constriction injury (CCI) model of neuropathic pain . Behavioural Brain Research.

Time-dependent characterisation of sex differences in the chronic constriction injury (CCI) model of neuropathic pain @article { author = {Joana Gonçalves and Diana Fonseca-Rodrigues and Inês Martins Laranjeira and Armando Almeida and Filipa Pinto-Ribeiro}, title = {Time-dependent characterisation of sex differences in the chronic constriction injury (CCI) model of neuropathic pain}, journal = {Behavioural Brain Research}, year = {2026}, month = {mar}, url = {https://doi.org/10.1016/j.bbr.2025.115990}, doi = {10.1016/j.bbr.2025.115990} } . Behavioural Brain Research.

Diana Fonseca-Rodrigues, Inês Laranjeira, Luiz Falconi-Sobrinho, Juliana Fiúza-Fernandes, Beatriz Soares, Luísa Pinto, Filipa Pinto-Ribeiro (2026). Same pain, different brainstem: Sex-dependent astrocytic activation in the rostral ventromedial medulla during experimental osteoarthritis . Osteoarthritis and Cartilage.

Same pain, different brainstem: Sex-dependent astrocytic activation in the rostral ventromedial medulla during experimental osteoarthritis @article { author = {Diana Fonseca-Rodrigues and Inês Laranjeira and Luiz Falconi-Sobrinho and Juliana Fiúza-Fernandes and Beatriz Soares and Luísa Pinto and Filipa Pinto-Ribeiro}, title = {Same pain, different brainstem: Sex-dependent astrocytic activation in the rostral ventromedial medulla during experimental osteoarthritis}, journal = {Osteoarthritis and Cartilage}, year = {2025}, month = {oct}, url = {https://doi.org/10.1016/j.joca.2025.10.006}, doi = {10.1016/j.joca.2025.10.006} } . Osteoarthritis and Cartilage.

Falconi-Sobrinho LL, Fonseca-Rodrigues D, Silva AL, da Silva JRT, Coimbra NC, Pinto-Ribeiro F(2025). Activation of NMDA Receptors in the Anterior Cingulate Cortex Enhances Anxiety-Induced Behaviour and Antinociception, and Contributes to the Modulation of Pain-Facilitatory Descending Pathways . European journal of pain (London, England).

Activation of NMDA Receptors in the Anterior Cingulate Cortex Enhances Anxiety-Induced Behaviour and Antinociception, and Contributes to the Modulation of Pain-Facilitatory Descending Pathways @article { author = {Falconi-Sobrinho, Luiz Luciano and Fonseca-Rodrigues, Diana and Silva, Ana Laura and da Silva, Josie Resende Torres and Coimbra, Norberto Cysne and Pinto-Ribeiro, Filipa}, title = {Activation of NMDA Receptors in the Anterior Cingulate Cortex Enhances Anxiety-Induced Behaviour and Antinociception, and Contributes to the Modulation of Pain-Facilitatory Descending Pathways}, journal = {European Journal of Pain}, volume = {29}, number = {6}, year = {2025}, month = {jun}, url = {https://doi.org/10.1002/ejp.70055}, doi = {10.1002/ejp.70055} } . European Journal of Pain.

Neuroanatomical and neurochemical substrates mediating fear-induced antinociception: A systematic review of rodent preclinical studies @article { author = {Falconi-Sobrinho, Luiz Luciano and Fonseca-Rodrigues, Diana and da Silva, Marcelo Lourenço and Coimbra, Norberto Cysne and Pinto-Ribeiro, Filipa}, title = {Neuroanatomical and neurochemical substrates mediating fear-induced antinociception: A systematic review of rodent preclinical studies}, journal = {Neuroscience & Biobehavioral Reviews}, volume = {168}, pages = {105959}, year = {2025}, month = {jan}, url = {https://doi.org/10.1016/j.neubiorev.2024.105959}, doi = {10.1016/j.neubiorev.2024.105959} } . Neuroscience & Biobehavioral Reviews.

Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance @article { author = {Guerra Leal, Bárbara and Carvalho, Cláudia and Santos, Cristina and Samões, Raquel and Martins-Ferreira, Ricardo and Teixeira, Catarina and Rodrigues, Diana and et al.}, title = {Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance}, journal = {Frontiers in Molecular Neuroscience}, volume = {17}, year = {2024}, month = {dec}, url = {https://doi.org/10.3389/fnmol.2024.1512860}, doi = {10.3389/fnmol.2024.1512860} } . Frontiers in Molecular Neuroscience.

Guerra Leal B, Carvalho C, Santos C, Samões R, Martins-Ferreira R, Teixeira C, Rodrigues D, Freitas J, Lemos C, Chorão R, et al.(2024). Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance . Frontiers in molecular neuroscience.

Falconi-Sobrinho LL, Fonseca-Rodrigues D, da Silva ML, Coimbra NC, Pinto-Ribeiro F(2024). Neuroanatomical and neurochemical substrates mediating fear-induced antinociception: A systematic review of rodent preclinical studies . Neuroscience and biobehavioral reviews.

Recent advances in the pharmacological treatment of chronic pain: a systematic review @article { author = {Fonseca-Rodrigues, Diana and Almeida, Armando and Pinto-Ribeiro, Filipa}, title = {Recent advances in the pharmacological treatment of chronic pain: a systematic review}, journal = {Revista DOR}, volume = {30}, number = {1}, year = {2024}, month = {jun}, url = {https://doi.org/10.24875/dor.m24000031}, doi = {10.24875/dor.m24000031} } . Revista DOR.

Ludmila de Souza Caputo, Carolina de Lima Alves, Inês Martins Laranjeira, Diana Fonseca-Rodrigues, Ademar Alves da Silva Filho, Alberto Carlos Pires Dias, Filipa Pinto-Ribeiro, Olavo dos Santos Pereira Junior, Ana Claudia Chagas de Paula, Akinori Cardozo Nagato, et al. (2024). Copaiba oil minimizes inflammation and promotes parenchyma re-epithelization in acute allergic asthma model induced by ovalbumin in BALB/c mice . Frontiers in Pharmacology.

Copaiba oil minimizes inflammation and promotes parenchyma re-epithelization in acute allergic asthma model induced by ovalbumin in BALB/c mice @article { author = {Ludmila de Souza Caputo and Carolina de Lima Alves and Inês Martins Laranjeira and Diana Fonseca-Rodrigues and Ademar Alves da Silva Filho and Alberto Carlos Pires Dias and Filipa Pinto-Ribeiro and Olavo dos Santos Pereira Junior and Ana Claudia Chagas de Paula and Akinori Cardozo Nagato and José Otávio do Amaral Corrêa}, title = {Copaiba oil minimizes inflammation and promotes parenchyma re-epithelization in acute allergic asthma model induced by ovalbumin in BALB/c mice}, journal = {Frontiers in Pharmacology}, year = {2024}, month = {apr}, url = {http://dx.doi.org/10.3389/fphar.2024.1356598}, doi = {10.3389/fphar.2024.1356598} } . Frontiers in Pharmacology.

Sucrose preference test: A systematic review of protocols for the assessment of anhedonia in rodents @article { author = {Maria João Primo and Diana Fonseca-Rodrigues and Armando Almeida and Pedro M. Teixeira and Filipa Pinto-Ribeiro}, title = {Sucrose preference test: A systematic review of protocols for the assessment of anhedonia in rodents}, journal = {European Neuropsychopharmacology}, year = {2023}, month = {dec}, url = {https://doi.org/10.1016/j.euroneuro.2023.08.496}, doi = {10.1016/j.euroneuro.2023.08.496} } . European Neuropsychopharmacology.

Maria João Primo, Diana Fonseca-Rodrigues, Armando Almeida, Pedro M. Teixeira, Filipa Pinto-Ribeiro (2023). Sucrose preference test: A systematic review of protocols for the assessment of anhedonia in rodents . European Neuropsychopharmacology.

Diana Amorim, Diana Fonseca-Rodrigues, Ana David-Pereira, Octávia Costa, Antónia Palhares Lima, Rosete Nogueira, Rute Cruz, Ana Sofia Martins, Liliana Sousa, Francisco Oliveira, et al. (2023). Injection of kaolin/carrageenan in the rat knee joint induces progressive experimental knee osteoarthritis . Pain.

Injection of kaolin/carrageenan in the rat knee joint induces progressive experimental knee osteoarthritis @article { author = {Diana Amorim and Diana Fonseca-Rodrigues and Ana David-Pereira and Octávia Costa and Antónia Palhares Lima and Rosete Nogueira and Rute Cruz and Ana Sofia Martins and Liliana Sousa and Francisco Oliveira and Hélder Pereira and Rogério Pirraco and Antti Pertovaara and Armando Almeida and Filipa Pinto-Ribeiro}, title = {Injection of kaolin/carrageenan in the rat knee joint induces progressive experimental knee osteoarthritis}, journal = {Pain}, year = {2023}, month = {jun}, url = {https://doi.org/10.1097/j.pain.0000000000002954}, doi = {10.1097/j.pain.0000000000002954} } . Pain.

Comparative neurotoxicity of dietary methylmercury and waterborne inorganic mercury in fish: Evidence of optic tectum vulnerability through morphometric and histopathological assessments @article { author = {Patrícia S. Carvalho and Diana Fonseca-Rodrigues and Mário Pacheco and Armando Almeida and Filipa Pinto-Ribeiro and Patrícia Pereira}, title = {Comparative neurotoxicity of dietary methylmercury and waterborne inorganic mercury in fish: Evidence of optic tectum vulnerability through morphometric and histopathological assessments}, journal = {Aquatic Toxicology}, pages = {106557--106557}, year = {2023}, month = {may}, url = {http://dx.doi.org/10.1016/j.aquatox.2023.106557}, doi = {10.1016/j.aquatox.2023.106557} } . Aquatic Toxicology.

Patrícia S. Carvalho, Diana Fonseca-Rodrigues, Mário Pacheco, Armando Almeida, Filipa Pinto-Ribeiro, Patrícia Pereira(2023). Comparative neurotoxicity of dietary methylmercury and waterborne inorganic mercury in fish: Evidence of optic tectum vulnerability through morphometric and histopathological assessments . Aquatic Toxicology. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 106557. Elsevier {BV}

Sucrose intake and preference by Wistar Han rats are not influenced by sex or food/water deprivation @article { author = {Diana Fonseca-Rodrigues}, title = {Sucrose intake and preference by Wistar Han rats are not influenced by sex or food/water deprivation}, journal = {Pharmacology Biochemistry and Behavior}, volume = {216}, pages = {173387--173387}, year = {2022}, month = {may}, url = {http://dx.doi.org/10.1016/j.pbb.2022.173387}, doi = {10.1016/j.pbb.2022.173387} } . Pharmacology Biochemistry and Behavior.

Diana Fonseca-Rodrigues(2022). Sucrose intake and preference by Wistar Han rats are not influenced by sex or food/water deprivation . Pharmacology Biochemistry and Behavior. 216. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 173387. Elsevier {BV}

A New Gal in Town: A Systematic Review of the Role of Galanin and Its Receptors in Experimental Pain @article { author = {Diana Fonseca-Rodrigues and Armando Almeida and Filipa Pinto-Ribeiro}, title = {A New Gal in Town: A Systematic Review of the Role of Galanin and Its Receptors in Experimental Pain}, journal = {Cells}, volume = {11}, number = {5}, pages = {839--839}, year = {2022}, month = {mar}, url = {https://doi.org/10.3390/cells11050839}, doi = {10.3390/cells11050839} } . Cells.

Diana Fonseca-Rodrigues, Armando Almeida, Filipa Pinto-Ribeiro(2022). A New Gal in Town: A Systematic Review of the Role of Galanin and Its Receptors in Experimental Pain . Cells. 11. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 839. {MDPI} {AG}

Diana Fonseca-Rodrigues, Armando Almeida, Filipa Pinto-Ribeiro (2022). A New Gal in Town: A Systematic Review of the Role of Galanin and Its Receptors in Experimental Pain . Cells.

Diana Fonseca-Rodrigues, André Rodrigues, Teresa Martins, Joana Pinto, Diana Amorim, Armando Almeida, Filipa Pinto-Ribeiro(2021). Correlation between pain severity and levels of anxiety and depression in osteoarthritis patients: a systematic review and meta-analysis . Rheumatology. Oxford University Press ({OUP})

Diana Fonseca-Rodrigues and Andr{\'{e}} Rodrigues and Teresa Martins and Joana Pinto and Diana Amorim and Armando Almeida and Filipa Pinto-Ribeiro(2021). Correlation between pain severity and levels of anxiety and depression in osteoarthritis patients: a systematic review and meta-analysis . Rheumatology. Oxford University Press ({OUP})

Diana Fonseca-Rodrigues and Diana Amorim and Armando Almeida and Filipa Pinto-Ribeiro(2021). Emotional and cognitive impairments in the peripheral nerve chronic constriction injury model (CCI) of neuropathic pain: A systematic review . Behavioural Brain Research. 399. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 113008. Elsevier {BV}

Diana Fonseca-Rodrigues and In{\^{e}}s Laranjeira and Jo{\~{a}}o Barbosa and Nuno Jorge Lamas and Diana Amorim and Armando Almeida and Filipa Pinto-Ribeiro(2021). Nociceptive, emotional, electrophysiological, and histological characterization of the chronic constriction injury model in female Wistar Han rats . Brain Research Bulletin. 167. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 56--70. Elsevier {BV}

CONFERENCE ABSTRACT

(2019). Nociceptive, emotional and electrophysiological characterization of the chronic constriction injury model of experimental traumatic neuropathic pain in female Wistar Han rats . Frontiers in Cellular Neuroscience.