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プロフィール詳細

プロジェクトを作成

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Dr. Dmitry V.に依頼

United States

プロフィール概要

I am a senior postdoctoral researcher in the area of neuroscience, genomics and bioinformatics. I currently focus on applying single-cell genomics methods to study human neurological and psychiatric diseases, including autism spectrum disorder and multiple sclerosis.

専門分野

• ☆ Biostatistics
• ☆ Genetics
• ☆ Genomics
• ☆ Neuroscience
• ☆ Big Data Analytics
• ☆ Statistics
• ☆ Bioinformatics
• ☆ Python
• ☆ Autism Spectrum Disorders
• ☆ Sclerosis & Demyelinating Diseases

サービス

• Writing
• Consulting
• Data & AI
• Product Development

職務経験

Postdoctoral scholar

University of California, San Francisco

4月 2016 - 現在

University of California San Francisco

4月 2016 - 現在

Graduate research assistant

University of Miami

8月 2011 - 4月 2016

学歴

PhD

University of Miami

8月 2011 - 4月 2016

MS

Moscow State University

9月 2009 - 5月 2011

BSc

Moscow State University

9月 2005 - 5月 2009

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Sorrells, S.F., Paredes, M.F., Velmeshev, D., Herranz-Pérez, V., Sandoval, K., Mayer, S., Chang, E.F., Insausti, R., Kriegstein, A.R., Rubenstein, J.L., et al.(2019). Immature excitatory neurons develop during adolescence in the human amygdala . Nature Communications. 10. (1).

(2019). Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex . Neuron. 102. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 143-158.e7.

(2019). Neuronal vulnerability and multilineage diversity in multiple sclerosis . Nature.

Velmeshev, D., Schirmer, L., Jung, D., Haeussler, M., Perez, Y., Mayer, S., Bhaduri, A., Goyal, N., Rowitch, D.H., Kriegstein, A.R.(2019). Single-cell genomics identifies cell type–specific molecular changes in autism . Science. 364. (6441). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 685-689.

Sartor, G.C., Powell, S.K., Velmeshev, D., Lin, D.Y., Magistri, M., Wiedner, H.J., Malvezzi, A.M., Andrade, N.S., Faghihi, M.A., Wahlestedt, C.(2017). Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens . Molecular and Cellular Neuroscience. 85. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 183-189.

Pardo, M., Cheng, Y., Velmeshev, D., Magistri, M., Eldar-Finkelman, H., Martinez, A., Faghihi, M.A., Jope, R.S., Beurel, E.(2017). Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice . JCI insight. 2. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e91782.

Grieco, S.F., Velmeshev, D., Magistri, M., Eldar-Finkelman, H., Faghihi, M.A., Jope, R.S., Beurel, E.(2017). Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3 . World Journal of Biological Psychiatry. 18. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 445-456.

(2017). Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex . Science. 358. (6368). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1318-1323.

Chang, K.-C., Hertz, J., Zhang, X., Jin, X.-L., Shaw, P., Derosa, B.A., Li, J.Y., Venugopalan, P., Valenzuela, D.A., Patel, R.D., et al.(2017). Novel regulatory mechanisms for the SoxC transcriptional network required for visual pathway development . Journal of Neuroscience. 37. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4967-4981.

Magistri, M., Khoury, N., Mazza, E.M.C., Velmeshev, D., Lee, J.K., Bicciato, S., Tsoulfas, P., Faghihi, M.A.(2016). A comparative transcriptomic analysis of astrocytes differentiation from human neural progenitor cells . European Journal of Neuroscience. 44. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2858-2870.

Magistri, M., Velmeshev, D., Makhmutova, M., Patel, P., Sartor, G.C., Volmar, C.-H., Wahlestedt, C., Faghihi, M.A.(2016). The BET-bromodomain inhibitor JQ1 reduces inflammation and tau phosphorylation at ser396 in the brain of the 3xTg model of Alzheimer’s disease . Current Alzheimer Research. 13. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 985-995.

Peschansky, V.J., Pastori, C., Zeier, Z., Wentzel, K., Velmeshev, D., Magistri, M., Silva, J.P., Wahlestedt, C.(2016). The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans . Molecular and Cellular Neuroscience. 74. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 49-57.

Velmeshev, D., Lally, P., Magistri, M., Faghihi, M.A.(2016). CANEapp: A user-friendly application for automated next generation transcriptomic data analysis . BMC Genomics. 17. (1).

Peschansky, V.J., Pastori, C., Zeier, Z., Motti, D., Wentzel, K., Velmeshev, D., Magistri, M., Bixby, J.L., Lemmon, V.P., Silva, J.P., et al.(2015). Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells . Frontiers in Genetics. 6. (Aug).

Trakhtenberg, E.F., Morkin, M.I., Patel, K.H., Fernandez, S.G., Sang, A., Shaw, P., Liu, X., Wang, Y., Mlacker, G.M., Gao, H., et al.(2015). The N-terminal set-β protein isoform induces neuronal death . Journal of Biological Chemistry. 290. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13417-13426.

Bobkova, N.V., Evgen'ev, M., Garbuz, D.G., Kulikov, A.M., Morozov, A., Samokhin, A., Velmeshev, D., Medvinskaya, N., Nesterova, I., Pollock, A., et al.(2015). Exogenous Hsp70 delays senescence and improves cognitive function in aging mice . Proceedings of the National Academy of Sciences of the United States of America. 112. (52). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 16006-16011.

Magistri, M., Velmeshev, D., Makhmutova, M., Faghihi, M.A.(2015). Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs . Journal of Alzheimer's Disease. 48. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 647-665.

Fatemi, R.P., Velmeshev, D., Faghihi, M.A.(2014). De-repressing LncRNA-targeted genes to upregulate gene expression: Focus on small molecule therapeutics . Molecular Therapy - Nucleic Acids. 3. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e196.

Pronin, A., Levay, K., Velmeshev, D., Faghihi, M., Shestopalov, V.I., Slepak, V.Z.(2014). Expression of olfactory signaling genes in the eye . PLoS ONE. 9. (4).

(2013). Calorie restriction alleviates the age-related decrease in neural progenitor cell division in the aging brain . European Journal of Neuroscience. 37. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1987-1993.

(2013). Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders . Molecular Autism. 4. (1).

BOOK

Magistri, M., Velmeshev, D.(2017). Identification of long noncoding RNAs associated to human disease susceptibility . Methods in Molecular Biology. 1543. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 197-208.

Pastori, C., Velmeshev, D., Peschansky, V.J.(2017). Deep-RACE: Comprehensive search for novel ncRNAs associated to a specific locus . Methods in Molecular Biology. 1543. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 129-143.