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プロフィール詳細
プロジェクトを作成
★★★★★
☆☆☆☆☆
Dr. Doorgesh Sharma J.に依頼
Singapore

Interdisciplinary scientist with expertise in Life Sciences, Biomedical Engineering, Computer Vision & Machine Learning

プロフィール概要
専門分野
サービス
Research Market Research, Feasibility Study
Consulting Scientific and Technical Consulting
Data & AI Statistical Analysis, Algorithm Design-Non ML, Data Visualization
Product Development Formulation
職務経験

Postdoctoral fellow

National University of Singapore (NUS)

3月 2020 - 現在

PhD Scholar

National University of Singapore (NUS), Mechanobiology Institute (MBI)

8月 2014 - 7月 2019

学歴

PhD

National University of Singapore (NUS), Mechanobiology Institute (MBI)

8月 2014 - 7月 2019

認定資格
  • 認定資格の詳細は未入力です。
出版物
JOURNAL ARTICLE
Venkatachalapathy, S., Jokhun, D.S., Shivashankar, G.V., Venkatachalapathy, S., Jokhun, D.S., Shivashankar, G.V.(2020). Multivariate analysis reveals activation-primed fibroblast geometric states in engineered 3D tumor microenvironments . Molecular biology of the cell. 31. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 803-812.
Doorgesh Sharma Jokhun, Farid Alisafaei, G. V. Shivashankar, Vivek B. Shenoy(2019). Regulation of nuclear architecture, mechanics, and nucleocytoplasmic shuttling of epigenetic factors by cell geometric constraints . Proceedings of the National Academy of Sciences. 116. (27). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13200--13209. Proceedings of the National Academy of Sciences
Alisafaei, F., Jokhun, D.S., Shivashankar, G.V., Shenoy, V.B., Alisafaei, F., Jokhun, D.S., Shivashankar, G.V., Shenoy, V.B.(2019). Regulation of nuclear architecture, mechanics, and nucleocytoplasmic shuttling of epigenetic factors by cell geometric constraints . Proceedings of the National Academy of Sciences of the United States of America. 116. (27). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13200-13209.
Damodaran, K., Crestani, M., Jokhun, D.S., Shivashankar, G.V., Damodaran, K., Crestani, M., Jokhun, D.S., Shivashankar, G.V.(2019). Nuclear morphometrics and chromatin condensation patterns as disease biomarkers using a mobile microscope . PLoS ONE. 14. (7).
Doorgesh Sharma Jokhun, Bibhas Roy, Saradha Venkatachalapathy, Prasuna Ratna, Yejun Wang, Mallika Nagarajan, G. V. Shivashankar(2018). Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors . Proceedings of the National Academy of Sciences. 115. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E4741--E4750. Proceedings of the National Academy of Sciences
Jokhun, D.S., Shang, Y., Shivashankar, G.V., Jokhun, D.S., Shang, Y., Shivashankar, G.V.(2018). Actin Dynamics Couples Extracellular Signals to the Mobility and Molecular Stability of Telomeres . Biophysical Journal. 115. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1166-1179.
Monticelli, M., Jokhun, D.S., Petti, D., Shivashankar, G.V., Bertacco, R., Monticelli, M., Jokhun, D.S., Petti, D., Shivashankar, G.V., Bertacco, R.(2018). Localized mechanical stimulation of single cells with engineered spatio-temporal profile . Lab on a Chip. 18. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2955-2965.
Damodaran, K., Venkatachalapathy, S., Alisafaei, F., Radhakrishnan, A.V., Jokhun, D.S., Shenoy, V.B., Shivashankar, G.V., Damodaran, K., Venkatachalapathy, S., Alisafaei, F., et al.(2018). Compressive force induces reversible chromatin condensation and cell geometry–dependent transcriptional response . Molecular Biology of the Cell. 29. (25). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3039-3051.
Krishnan, V., Chong, Y.L., Tan, T.Z., Kulkarni, M., Bin Rahmat, M.B., Tay, L.S., Sankar, H., Jokhun, D.S., Ganesan, A., Chuang, L.S.H., et al.(2018). TGFβ promotes genomic instability after loss of RUNX3 . Cancer Research. 78. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 88-102.
Roy, B., Venkatachalapathy, S., Ratna, P., Wang, Y., Jokhun, D.S., Nagarajan, M., Shivashankar, G.V., Roy, B., Venkatachalapathy, S., Ratna, P., et al.(2018). Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors . Proceedings of the National Academy of Sciences of the United States of America. 115. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E4741-E4750.
Doorgesh Sharma Jokhun, Aninda Mitra, Saradha Venkatachalapathy, Prasuna Ratna, Yejun Wang, G. V. Shivashankar(2017). Cell geometry dictates {TNF}$\upalpha$-induced genome response . Proceedings of the National Academy of Sciences. 114. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E3882--E3891. Proceedings of the National Academy of Sciences
A.V. Radhakrishnan, Doorgesh S. Jokhun, Saradha Venkatachalapathy, G.V. Shivashankar(2017). Nuclear Positioning and Its Translational Dynamics Are Regulated by Cell Geometry . Biophysical Journal. 112. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1920--1928. Elsevier {BV}
Mitra, A., Venkatachalapathy, S., Ratna, P., Wang, Y., Jokhun, D.S., Shivashankar, G.V., Mitra, A., Venkatachalapathy, S., Ratna, P., Wang, Y., et al.(2017). Cell geometry dictates TNFα-induced genome response . Proceedings of the National Academy of Sciences of the United States of America. 114. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E3882-E3891.
Radhakrishnan, A.V., Jokhun, D.S., Venkatachalapathy, S., Shivashankar, G.V., Radhakrishnan, A.V., Jokhun, D.S., Venkatachalapathy, S., Shivashankar, G.V.(2017). Nuclear Positioning and Its Translational Dynamics Are Regulated by Cell Geometry . Biophysical Journal. 112. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1920-1928.
Makhija, E., Jokhun, D.S., Shivashankar, G.V., Makhija, E., Jokhun, D.S., Shivashankar, G.V.(2016). Nuclear deformability and telomere dynamics are regulated by cell geometric constraints . Proceedings of the National Academy of Sciences of the United States of America. 113. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E32-E40.
Movahednia, M.M., Kidwai, F.K., Jokhun, D.S., Squier, C.A., Toh, W.S., Cao, T., Movahednia, M.M., Kidwai, F.K., Jokhun, D.S., Squier, C.A., et al.(2016). Potential applications of keratinocytes derived from human embryonic stem cells . Biotechnology Journal. 11. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 58-70.
Ekta Makhija, D.S. Jokhun, G.V. Shivashankar(2015). Acto-Myosin Contractility Regulates Nuclear and Chromatin Plasticity . Biophysical Journal. 108. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 541a--542a. Elsevier {BV}
Mohammad M. Movahednia, Fahad K. Kidwai, Doorgesh S. Jokhun, Christopher A. Squier, Wei Seong Toh, Tong Cao(2015). Potential applications of keratinocytes derived from human embryonic stem cells . Biotechnology Journal. 11. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 58--70. Wiley-Blackwell
Ekta Makhija, D. S. Jokhun, G. V. Shivashankar(2015). Nuclear deformability and telomere dynamics are regulated by cell geometric constraints . Proceedings of the National Academy of Sciences. 113. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E32--E40. Proceedings of the National Academy of Sciences
Kidwai, F.K., Movahednia, M.M., Iqbal, K., Jokhun, D.S., Cao, T., Fawzy, A.S., Kidwai, F.K., Movahednia, M.M., Iqbal, K., Jokhun, D.S., et al.(2014). Human embryonic stem cell differentiation into odontoblastic lineage: An in vitro study . International Endodontic Journal. 47. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 346-355.
F. K. Kidwai, M. M. Movahednia, K. Iqbal, D. S. Jokhun, T. Cao, A. S. Fawzy(2013). Human embryonic stem cell differentiation into odontoblastic lineage: anin vitrostudy . International Endodontic Journal. 47. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 346--355. Wiley-Blackwell
Doorgesh Sharma Jokhun, Fahad Karim Kidwai, Mohammad Mehdi Movahednia, Jin Fei Yeo, Kai Soo Tan, Tong Cao(2013). Human embryonic stem cells derived keratinocyte as anin vitroresearch model for the study of immune response . Journal of Oral Pathology {\&} Medicine. 42. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 627--634. Wiley-Blackwell
Fahad K. Kidwai, Hua Liu, Wei Seong Toh, Xin Fu, Doorgesh S. Jokhun, Mohammad M. Movahednia, Mingming Li, Yu Zou, Christopher A. Squier, Toan T. Phan, et al.(2013). Differentiation of Human Embryonic Stem Cells into Clinically Amenable Keratinocytes in an Autogenic Environment . Journal of Investigative Dermatology. 133. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 618--628. Elsevier {BV}
Kidwai, F.K., Jokhun, D.S., Movahednia, M.M., Yeo, J.F., Tan, K.S., Cao, T., Kidwai, F.K., Jokhun, D.S., Movahednia, M.M., Yeo, J.F., et al.(2013). Human embryonic stem cells derived keratinocyte as an in vitro research model for the study of immune response . Journal of Oral Pathology and Medicine. 42. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 627-634.
Kidwai, F.K., Liu, H., Toh, W.S., Fu, X., Jokhun, D.S., Movahednia, M.M., Li, M., Zou, Y., Squier, C.A., Phan, T.T., et al.(2013). Differentiation of human embryonic stem cells into clinically amenable keratinocytes in an autogenic environment . Journal of Investigative Dermatology. 133. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 618-628.
BOOK CHAPTER
(2018). Cell Geometric Control of Nuclear Dynamics and Its Implications . Mechanobiology in Health and Disease.
Kumar, A., Makhija, E., Radhakrishnan, A.V., Jokhun, D.S., Shivashankar, G.V., Kumar, A., Makhija, E., Radhakrishnan, A.V., Jokhun, D.S., Shivashankar, G.V.(2018). Cell geometric control of nuclear dynamics and its implications . Mechanobiology in Health and Disease. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 55-76.