プロフィール詳細

プロジェクトを作成

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Dr. Eleonora P.に依頼

Switzerland

PhD Molecular Biologist | Biomedical Research | Medical Writing | Scientific Consulting | AI Evaluation

プロフィール概要

I am a PhD Molecular Biologist with over 20 years of experience in biomedical research at the Universities of Bern and Zurich, Switzerland. My expertise includes molecular biology, cell biology, physiology, hepatology, mitochondrial biology, metabolism, and translational biomedical research. Throughout my academic career I have authored more than 35 peer-reviewed scientific publications and have extensive experience in experimental design, data interpretation, scientific writing, literature review, manuscript editing, journal selection, and research consulting. I help researchers, biotechnology companies, healthcare organizations, and startups with: • Scientific consulting • Literature reviews • Research strategy • Manuscript editing • Journal selection • Grant support • Medical and scientific writing • AI training and expert evaluation I am committed to delivering scientifically rigorous, accurate, and practical solutions tailored to each project.

専門分野

• ★ Technical & Scientific Writing
• ★ Scientific Proofreading & Editing
• ★ Grant Writing
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ PCR
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Gene Regulation
• ☆ Histology
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Electron Microscopy
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Immunohistochemistry
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Survey Design & Methodology
• ☆ Medical Content Writing
• ☆ Journal Selection
• ☆ Proofreading & Editing
• ☆ Course Content Writing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, General Proofreading & Editing

Research Meta-Research, Technology Scouting, Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Image Analysis, Text Mining & Analytics, Data Insights

Product Development Product Evaluation

職務経験

University of Zurich

1月 2015 - 現在

Senior Research Scientist

University of Zurich (UZH), Zurich, Switzerland

1月 2015 - 9月 2021

Postdoctoral Researcher

University of Bern

11月 2005 - 1月 2015

学歴

PhD-Life Sciences

Friedrich-Alexander Universität Erlangen-Nürnberg - Germany

1月 2002 - 5月 2005

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Eleonora Patsenker, Veera Raghavan Thangapandi, Oskar Knittelfelder, Alessandra Palladini, Michaela Hefti, Jane Beil-Wagner, Gerhard Rogler, Thorsten Buch, Andrej Shevchenko, Jochen Hampe, et al.(2022). The PNPLA3 variant I148M reveals protective effects toward hepatocellular carcinoma in mice via restoration of omega-3 polyunsaturated fats . The Journal of Nutritional Biochemistry. 108. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 109081. Elsevier {BV}

Weder B, Schefer F, van Haaften WT, Patsenker E, Stickel F, Mueller S, Hutter S, Schuler C, Baebler K, Wang Y, et al.(2022). New Therapeutic Approach for Intestinal Fibrosis Through Inhibition of pH-Sensing Receptor GPR4 . Inflammatory bowel diseases.

Thangapandi VR, Knittelfelder O, Brosch M, Patsenker E, Vvedenskaya O, Buch S, Hinz S, Hendricks A, Nati M, Herrmann A, et al.(2020). Loss of hepatic Mboat7 leads to liver fibrosis . Gut.

Moncsek A, Al-Suraih MS, Trussoni CE, O'Hara SP, Splinter PL, Zuber C, Patsenker E, Valli PV, Fingas CD, Weber A, et al.(2017). Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2^-/- ) mice . Hepatology (Baltimore, Md.).

Patsenker E, Chicca A, Petrucci V, Moghadamrad S, de Gottardi A, Hampe J, Gertsch J, Semmo N, Stickel F(2017). 4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice . Journal of molecular medicine (Berlin, Germany).

Dondorf F, Fahrner R, Ardelt M, Patsenker E, Stickel F, Dahmen U, Settmacher U, Rauchfuß F(2017). Induction of chronic cholestasis without liver cirrhosis - Creation of an animal model . World journal of gastroenterology.

Patsenker E, Stickel F(2016). Cannabinoids in liver diseases . Clinical liver disease.

Mahli A, Thasler WE, Patsenker E, Müller S, Stickel F, Müller M, Seitz HK, Cederbaum AI, Hellerbrand C(2015). Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro . Oncotarget.

Patsenker E, Sachse P, Chicca A, Gachet MS, Schneider V, Mattsson J, Lanz C, Worni M, de Gottardi A, Semmo M, et al.(2015). Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation . International journal of molecular sciences.

K⁺-channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells. @article{PMID:25212242, title = {K⁺-channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells.}, author = {Freise C and Heldwein S and Erben U and Hoyer J and Köhler R and Jöhrens K and Patsenker E and Ruehl M and Seehofer D and Stickel F and Somasundaram R}, doi = {10.1111/liv.12681}, journal = {Liver international : official journal of the International Association for the Study of the Liver}, month = {04}, year = {2015} } . Liver international : official journal of the International Association for the Study of the Liver.

Fahrner R, Patsenker E, de Gottardi A, Stickel F, Montani M, Stroka D, Candinas D, Beldi G(2014). Elevated liver regeneration in response to pharmacological reduction of elevated portal venous pressure by terlipressin after partial hepatectomy . Transplantation.

von Schönfels W, Patsenker E, Fahrner R, Itzel T, Hinrichsen H, Brosch M, Erhart W, Gruodyte A, Vollnberg B, Richter K, et al.(2014). Metabolomic tissue signature in human non-alcoholic fatty liver disease identifies protective candidate metabolites . Liver international : official journal of the International Association for the Study of the Liver.

Patsenker E, Popov Y, Stickel F, Schneider V, Ledermann M, Sägesser H, Niedobitek G, Goodman SL, Schuppan D(2009). Pharmacological inhibition of integrin alphavbeta3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis . Hepatology (Baltimore, Md.).

Wang Y, Millonig G, Nair J, Patsenker E, Stickel F, Mueller S, Bartsch H, Seitz HK(2009). Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease . Hepatology (Baltimore, Md.).

Stickel F, Droz S, Patsenker E, Bögli-Stuber K, Aebi B, Leib SL(2008). Severe hepatotoxicity following ingestion of Herbalife nutritional supplements contaminated with Bacillus subtilis . Journal of hepatology.

Lukivskaya O, Patsenker E, Lis R, Buko VU(2008). Inhibition of inducible nitric oxide synthase activity prevents liver recovery in rat thioacetamide-induced fibrosis reversal . European journal of clinical investigation.

Patsenker E, Popov Y, Stickel F, Jonczyk A, Goodman SL, Schuppan D(2008). Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression . Gastroenterology.

Stickel F, Osterreicher CH, Halangk J, Berg T, Homann N, Hellerbrand C, Patsenker E, Schneider V, Kolb A, Friess H, et al.(2008). No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease . Alcoholism, clinical and experimental research.

Osterreicher CH, Halangk J, Berg T, Patsenker E, Homann N, Hellerbrand C, Seitz HK, Eurich D, Stickel F(2008). Evaluation of the transforming growth factor beta1 codon 25 (Arg-->Pro) polymorphism in alcoholic liver disease . Cytokine.

Popov Y, Patsenker E, Stickel F, Zaks J, Bhaskar KR, Niedobitek G, Kolb A, Friess H, Schuppan D(2008). Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies . Journal of hepatology.

Lukivskaya O, Patsenker E, Buko VU(2007). Protective effect of ursodeoxycholic acid on liver mitochondrial function in rats with alloxan-induced diabetes: link with oxidative stress . Life sciences.

Patsenker E, Popov Y, Wiesner M, Goodman SL, Schuppan D(2006). Pharmacological inhibition of the vitronectin receptor abrogates PDGF-BB-induced hepatic stellate cell migration and activation in vitro . Journal of hepatology.

Popov Y, Patsenker E, Bauer M, Niedobitek E, Schulze-Krebs A, Schuppan D(2006). Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB . The Journal of biological chemistry.

Li ZD, Bork JP, Krueger B, Patsenker E, Schulze-Krebs A, Hahn EG, Schuppan D(2005). VEGF induces proliferation, migration, and TGF-beta1 expression in mouse glomerular endothelial cells via mitogen-activated protein kinase and phosphatidylinositol 3-kinase . Biochemical and biophysical research communications.

Stickel F, Patsenker E, Schuppan D(2005). Herbal hepatotoxicity . Journal of hepatology.

Popov Y, Patsenker E, Fickert P, Trauner M, Schuppan D(2005). Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes . Journal of hepatology.

Dan Z, Popov Y, Patsenker E, Preimel D, Liu C, Wang XD, Seitz HK, Schuppan D, Stickel F(2005). Hepatotoxicity of alcohol-induced polar retinol metabolites involves apoptosis via loss of mitochondrial membrane potential . FASEB journal : official publication of the Federation of American Societies for Experimental Biology.