プロフィール詳細

プロジェクトを作成

★★★★★

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★★★★★

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Dr. Emily C.に依頼

United States

Biochemist with expertise in molecular diagnostics of infectious disease, including NGS and CRISPR-based methods

プロフィール概要

For eight months in 2020 I lead a team of scientists and volunteers running the CLIAHUB COVID-19 clinical diagnostics lab at UCSF/CZ Biohub. Prior to COVID, I developed CRISPR-based targeted Next Gen Sequencing methods.

専門分野

• ★ COVID-19
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Next Generation Sequencing (NGS)
• ☆ Gene Editing/CRISPR
• ☆ Infectious Disease

サービス

• Writing
• Research
• Consulting

Writing Technical Writing, Copywriting, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

職務経験

Assistant Adjunct Professor

University of California San Francisco

2019 - 現在

Group Leader

CZ Biohub

2016 - 2020

Postdoc

University of California, San Francisco

2014 - 2016

Postdoc

German Center for Neurodegenerative Diseases

2012 - 2013

Research Associate

Broad Institute

2003 - 2005

学歴

PhD (Chemistry and Chemical Biology)

University of California, San Francisco

2005 - 2012

AB (Department of Molecular, Cellular and Developmental Biology)

Bryn Mawr College

1999 - 2003

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Bálint Csörgő, Lina M. León, Ilea J. Chau-Ly, Alejandro Vasquez-Rifo, Joel D. Berry, Caroline Mahendra, Emily D. Crawford, Jennifer D. Lewis, Joseph Bondy-Denomy(2020). A compact Cascade{\textendash}Cas3 system for targeted genome engineering . Nature Methods. Springer Science and Business Media {LLC}

Manu Vanaerschot, Sabrina A. Mann, James T. Webber, Jack Kamm, Sidney M. Bell, John Bell, Si Noon Hong, Minh Phuong Nguyen, Lienna Y. Chan, Karan D. Bhatt, et al.(2020). Identification of a polymorphism in the N gene of {SARS}-{CoV}-2 that adversely impacts detection by {RT}-{PCR} . Journal of Clinical Microbiology. American Society for Microbiology

Emily D. Crawford, Irene Acosta, Vida Ahyong, Erika C. Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S. Azimi, Caleigh M. Azumaya, et al. (2020). Rapid deployment of SARS-CoV-2 testing: The CLIAHUB . PLOS Pathogens.

Kristoffer E. Leon, Ryan D. Schubert, Didac Casas-Alba, Isobel A. Hawes, Prashanth S. Ramachandran, Akshaya Ramesh, John E. Pak, Wesley Wu, Carly K. Cheung, Emily D. Crawford, et al. (2020). Genomic and serologic characterization of enterovirus A71 brainstem encephalitis . Neurology - Neuroimmunology Neuroinflammation.

E. Rackaityte, J. Halkias, E. M. Fukui, V. F. Mendoza, C. Hayzelden, E. D. Crawford, K. E. Fujimura, T. D. Burt, S. V. Lynch(2020). Viable bacterial colonization is highly limited in the human intestine in utero . Nature Medicine. Springer Science and Business Media {LLC}

Leon, K.E., Schubert, R.D., Casas-Alba, D., Hawes, I.A., Ramachandran, P.S., Ramesh, A., Pak, J.E., Wu, W., Cheung, C.K., Crawford, E.D., et al.(2020). Genomic and serologic characterization of enterovirus A71 brainstem encephalitis . Neurology(R) neuroimmunology & neuroinflammation. 7. (3).

Crawford, E., Kamm, J., Miller, S., Li, L.M., Caldera, S., Lyden, A., Yokoe, D., Nichols, A., Tran, N.K., Barnard, S.E., et al.(2020). Investigating transfusion-related sepsis using culture-independent metagenomic sequencing . Clinical Infectious Diseases. 71. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1179-1185.

Fridey, J.L., Stramer, S.L., Nambiar, A., Moayeri, M., Bakkour, S., Langelier, C., Crawford, E., Lu, T., Lanteri, M.C., Kamm, J., et al.(2020). Sepsis from an apheresis platelet contaminated with Acinetobacter calcoaceticus/baumannii complex bacteria and Staphylococcus saprophyticus after pathogen reduction . Transfusion. 60. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1960-1969.

Rackaityte, E., Halkias, J., Fukui, E.M., Mendoza, V.F., Hayzelden, C., Crawford, E.D., Fujimura, K.E., Burt, T.D., Lynch, S.V.(2020). Viable bacterial colonization is highly limited in the human intestine in utero . Nature Medicine. 26. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 599-607.

Crawford, E.D., Acosta, I., Ahyong, V., Anderson, E.C., Arevalo, S., Asarnow, D., Axelrod, S., Ayscue, P., Azimi, C.S., Azumaya, C.M., et al.(2020). Rapid deployment of SARS-CoV-2 testing: The CLIAHUB . PLoS Pathogens. 16. (10).

Briggs, J., Teyssier, N., Nankabirwa, J.I., Rek, J., Jagannathan, P., Arinaitwe, E., Bousema, T., Drakeley, C., Murray, M., Crawford, E., et al.(2020). Sex-based differences in clearance of chronic plasmodium falciparum infection . eLife. 9. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1-14.

Csörgő, B., León, L.M., Chau-Ly, I.J., Vasquez-Rifo, A., Berry, J.D., Mahendra, C., Crawford, E.D., Lewis, J.D., Bondy-Denomy, J.(2020). A compact Cascade–Cas3 system for targeted genome engineering . Nature Methods. 17. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1183-1190.

Parinaz Fozouni, Sungmin Son, María Díaz de León Derby, Gavin J. Knott, Carley N. Gray, Michael V. D’Ambrosio, Chunyu Zhao, Neil A. Switz, G. Renuka Kumar, Stephanie I. Stephens, et al.(2020). Amplification-free detection of {SARS}-{CoV}-2 with {CRISPR}-Cas13a and mobile phone microscopy . Cell. Elsevier {BV}

Ramachandran, P.S., Cresswell, F.V., Meya, D.B., Langelier, C., Crawford, E.D., Derisi, J.L., Boulware, D.R., Wilson, M.R.(2019). Detection of Cryptococcus DNA by Metagenomic Next-generation Sequencing in Symptomatic Cryptococcal Antigenemia . Clinical Infectious Diseases. 68. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1978-1979.

Quan, J., Langelier, C., Kuchta, A., Batson, J., Teyssier, N., Lyden, A., Caldera, S., McGeever, A., Dimitrov, B., King, R., et al.(2019). FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences . Nucleic acids research. 47. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e83.

Schubert, R.D., Hawes, I.A., Ramachandran, P.S., Ramesh, A., Crawford, E.D., Pak, J.E., Wu, W., Cheung, C.K., O’Donovan, B.D., Tato, C.M., et al.(2019). Pan-viral serology implicates enteroviruses in acute flaccid myelitis . Nature Medicine. 25. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1748-1752.

Zinter, M.S., Dvorak, C.C., Mayday, M.Y., Iwanaga, K., Ly, N.P., McGarry, M.E., Church, G.D., Faricy, L.E., Rowan, C.M., Hume, J.R., et al.(2019). Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children . Clinical Infectious Diseases. 68. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1847-1855.

Woodworth, M.H., Dynerman, D., Crawford, E.D., Doernberg, S.B., Ramirez-Avila, L., Serpa, P.H., Nichols, A., Li, L.M., Lyden, A., Tato, C.M., et al.(2019). Sentinel case of Candida auris in the Western United States following prolonged occult colonization in a returned traveler from India . Microbial Drug Resistance. 25. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 677-680.

Saha, S., Ramesh, A., Kalantar, K., Malaker, R., Hasanuzzaman, M., Khan, L.M., Mayday, M.Y., Sajib, M.S.I., Li, L.M., Langelier, C., et al.(2019). Unbiased metagenomic sequencing for pediatric meningitis in bangladesh reveals neuroinvasive chikungunya virus outbreak and other unrealized pathogens . mBio. 10. (6).

Qu, J., Prasad, N.K., Yu, M.A., Chen, S., Lyden, A., Herrera, N., Silvis, M.R., Crawford, E., Looney, M.R., Peters, J.M., et al.(2019). Modulating pathogenesis with MOBILE-CRISPRI . Journal of Bacteriology. 201. (22).

Mulliken, J.S., Langelier, C., Budak, J.Z., Miller, S., Dynerman, D., Hao, S., Li, L.M., Crawford, E., Lyden, A., Woodworth, M.H., et al.(2019). Bergeyella cardium: Clinical characteristics and draft genome of an emerging pathogen in native and prosthetic valve endocarditis . Open Forum Infectious Diseases. 6. (4).

Langelier, C., Kalantar, K.L., Moazed, F., Wilson, M.R., Crawford, E.D., Deiss, T., Belzer, A., Bolourchi, S., Caldera, S., Fung, M., et al.(2018). Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults . Proceedings of the National Academy of Sciences of the United States of America. 115. (52). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E12353-E12362.

Emily D. Crawford, Hodaka Fujii, Jenai Quan, Jeremy A. Horst, Daniel Ebert, Wesley Wu, Joseph L. DeRisi(2017). Plasmid-free {CRISPR}/Cas9 genome editing in Plasmodium falciparum confirms mutations conferring resistance to the dihydroisoquinolone clinical candidate {SJ}733 . {PLOS} {ONE}. 12. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e0178163. Public Library of Science ({PLoS})

Crawford, E.D., Quan, J., Horst, J.A., Ebert, D., Wu, W., DeRisi, J.L.(2017). Plasmid-free CRISPR/Cas9 genome editing in Plasmodium falciparum confirms mutations conferring resistance to the dihydroisoquinolone clinical candidate SJ733 . PLoS ONE. 12. (5).

Krings, G., Joseph, N.M., Bean, G.R., Solomon, D., Onodera, C., Talevich, E., Yeh, I., Grenert, J.P., Hosfield, E., Crawford, E.D., et al.(2017). Genomic profiling of breast secretory carcinomas reveals distinct genetics from other breast cancers and similarity to mammary analog secretory carcinomas . Modern Pathology. 30. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1086-1099.

Wilson, M.R., Zimmermann, L.L., Crawford, E.D., Sample, H.A., Soni, P.R., Baker, A.N., Khan, L.M., DeRisi, J.L.(2017). Acute West Nile Virus Meningoencephalitis Diagnosed Via Metagenomic Deep Sequencing of Cerebrospinal Fluid in a Renal Transplant Patient . American Journal of Transplantation. 17. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 803-808.

Gu, W., Crawford, E.D., O'Donovan, B.D., Wilson, M.R., Chow, E.D., Retallack, H., DeRisi, J.L.(2016). Depletion of Abundant Sequences by Hybridization (DASH): Using Cas9 to remove unwanted high-abundance species in sequencing libraries and molecular counting applications . Genome Biology. 17. (1).

Doan, T., Wilson, M.R., Crawford, E.D., Chow, E.D., Khan, L.M., Knopp, K.A., O'Donovan, B.D., Xia, D., Hacker, J.K., Stewart, J.M., et al.(2016). Erratum to: Illuminating uveitis: Metagenomic deep sequencing identifies common and rare pathogens [Genome Medicine, 8 (2016) (123)] . Genome Medicine. 8. (1).

Doan, T., Wilson, M.R., Crawford, E.D., Chow, E.D., Khan, L.M., Knopp, K.A., O'Donovan, B.D., Xia, D., Hacker, J.K., Stewart, J.M., et al.(2016). Illuminating uveitis: Metagenomic deep sequencing identifies common and rare pathogens . Genome Medicine. 8. (1).

Crawford, E.D., Seaman, J.E., Agard, N., Hsu, G.W., Julien, O., Mahrus, S., Nguyen, H., Shimbo, K., Yoshihara, H.A.I., Zhuang, M., et al.(2013). The degrabase: A database of proteolysis in healthy and apoptotic human cells . Molecular and Cellular Proteomics. 12. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 813-824.

Crawford, E.D., Seaman, J.E., Barber, A.E., David, D.C., Babbitt, P.C., Burlingame, A.L., Wells, J.A.(2012). Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis . Cell Death and Differentiation. 19. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2040-2048.

Root, B.C., Pellegrino, L.D., Crawford, E.D., Kokona, B., Fairman, R.(2009). Design of a heterotetrameric coiled coil . Protein Science. 18. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 329-336.

Lamb, J., Crawford, E.D., Peck, D., Modell, J.W., Blat, I.C., Wrobel, M.J., Lerner, J., Brunet, J.-P., Subramanian, A., Ross, K.N., et al.(2006). The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease . Science. 313. (5795). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1929-1935.

Peck, D., Crawford, E.D., Ross, K.N., Stegmaier, K., Golub, T.R., Lamb, J.(2006). A method for high-throughput gene expression signature analysis . Genome Biology. 7. (7).

Wagner, D.E., Phillips, C.L., Ali, W.M., Nybakken, G.E., Crawford, E.D., Schwab, A.D., Smith, W.F., Fairman, R.(2005). Toward the development of peptide nanofilaments and nanoropes as smart materials . Proceedings of the National Academy of Sciences of the United States of America. 102. (36). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 12656-12661.

OTHER

Emily Crawford, Peter Cooch, Annalisa Watson, Apryl Olarte, Joe DeRisi, Bryan Greenhouse, Jill Hakim, Keirstinne Turcios, Lee Atkinson-McEvoy, Raphael Hirsch, et al.(2020). Supervised self-collected {SARS}-{CoV}-2 testing in indoor summer camps to inform school reopening . Cold Spring Harbor Laboratory

BOOK

Crawford, E.D., Wells, J.A.(2011). Caspase substrates and cellular remodeling . Annual Review of Biochemistry. 80. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1055-1087.