プロフィール詳細

プロジェクトを作成

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Dr. Erin W.に依頼

United States

Human & Animal Health | Precision Medicine | Translational Medicine | Research & Development

プロフィール概要

Ph.D.-trained leader in clinical science, biomarker analytics, statistical genetics, and precision medicine with 10+ years of experience in pharmaceutical and biotechnology environments. Expertise includes oncology clinical trial analytics, study and protocol development, biomarker strategy and validation, molecular diagnostics, next-generation sequencing, bioinformatics, and multi-omics integration across the drug development lifecycle from target identification through Phase III and regulatory submission. Proven track record leading complex clinical and biomarker programs within scope, budget, timelines, and quality standards. Author and reviewer of protocols, statistical analysis plans, study reports, publications, and regulatory deliverables in compliance with SOPs, QA/QC, GxP, and regulatory guidelines. Developer of reproducible SAS and R workflows using clinical, real-world, CDISC-compliant, and multi-omics datasets to support data validation, outlier detection, and biomarker discovery across diagnostic, predictive, prognostic, and safety applications. Experience spans molecular research, clinical trial, drug target development, and genetic epidemiology in oncology (breast, lung, brain, colorectal, and other cancers), immunological disease, neurodegenerative disease, neuropsychiatric disorders, ophthalmology, cardiovascular disease, and muscle biology. Experience managing large-scale biological sample cohorts and contributing to peer-reviewed publications. Skilled in translating complex clinical and molecular data into actionable insights for cross-functional stakeholders. Leadership of multidisciplinary teams including statisticians, scientists, statistical geneticists, analysts, and external CRO partners, with responsibility for hiring, mentoring, and resource planning. Recognized for strong scientific judgment, proactive risk identification, and consistent delivery in global, matrixed environments.

専門分野

• ★ Biomarkers
• ★ Genetics
• ★ Drug Target Identification
• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Microarrays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Proteomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ PCR
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Synthetic Genomics
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Exome Sequencing
• ☆ RNA Sequencing
• ☆ Cell Biology
• ☆ Neuroscience
• ☆ Neuropharmacology
• ☆ Neurobiology
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Biotechnology & Bioengineering
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Data Analysis
• ☆ Image Processing
• ☆ Data Processing
• ☆ Data Exploration
• ☆ Cluster Analysis
• ☆ Data Visualization
• ☆ Big Data Analytics
• ☆ Data Collection
• ☆ Data Management
• ☆ Data Manipulation
• ☆ Machine Learning
• ☆ Data Cleaning
• ☆ Artificial Intelligence
• ☆ Data Security
• ☆ Statistics
• ☆ Meta-Analysis
• ☆ Regression Analysis
• ☆ Multivariate Analysis
• ☆ Nonlinear Regression
• ☆ Correlation Analysis
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Structural Bioinformatics
• ☆ Agricultural Biotechnology
• ☆ Immunohistochemistry
• ☆ Population Genetics
• ☆ Information & Knowledge Management
• ☆ Data Storage
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Drug Development
• ☆ Preclinical Research
• ☆ Pharmacogenomics
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Survey Design & Methodology
• ☆ Literature Search
• ☆ Gap Analysis
• ☆ Skills Training

サービス

• Writing
• Research
• Consulting

Writing Technical Writing

Research Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Operations Consulting, Scientific and Technical Consulting

職務経験

DIRECTOR, BIOMARKER ANALYTICS

CENCORA, INC.

2月 2016 - 7月 2026

SPECIAL AND SCIENTIFIC STATISTICAL GENETICIST/GENETIC EPIDEMIOLOGIST

TUFTS MEDICAL CENTER - OPHTHALMIC EPIDEMIOLOGY AND GENETICS SERVICE

10月 2014 - 1月 2016

Postdoctoral Fellow

Indiana University/Purdue University at Indianapolis

7月 2011 - 10月 2014

GRADUATE RESEARCH AND TEACHING ASSISTANT: MOLECULAR GENETICS

The University of Illinois at Urbana-Champaign

8月 2004 - 4月 2011

UNDERGRADUATE RESEARCH ASSISTANT: MOLECULAR GENETICS

University of Illinois at Urbana Champaign

10月 2001 - 7月 2004

学歴

Doctor of Philosophy (Ph.D)

University of Illinois at Urbana-Champaign

8月 2004 - 4月 2011

Bachelor of Science (Honours)

University of Illinois at Urbana-Champaign

8月 2000 - 5月 2004

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Gerraty RT, Provost A, Li L, Wagner E, Haas M, Lancashire L (2023). Machine learning within the Parkinson's progression markers initiative: Review of the current state of affairs . Frontiers in aging neuroscience.

Saleh M, Cassier PA, Eberst L, Naik G, Morris VK, Pant S, Terret C, Gao L, Long A, Mao H, et al. (2020). Phase I Study of Ramucirumab Plus Merestinib in Previously Treated Metastatic Colorectal Cancer: Safety, Preliminary Efficacy, and Pharmacokinetic Findings . The oncologist.

Rockhold F, Bromley C, Wagner EK, Buyse M (2019). Open science: The open clinical trials data journey . Clinical trials (London, England).

Miri Cohen-Zinder, Ala Orlov, Olena Trofimyuk, Rotem Agmon, Rame Kabiya, Einav Shor-Shimoni, Erin K. Wagner, Karen Hussey, Haim Leibovich, Joshua Miron, et al. (2017). Dietary supplementation of Moringa oleifera silage increases meat tenderness of Assaf lambs . Small Ruminant Research.

Wagner EK, Raje S, Amos L, Kurata J, Badve AS, Li Y, Busby B (2017). Extending TCGA queries to automatically identify analogous genomic data from dbGaP . F1000Research.

Yu Y, Wagner EK, Souied EH, Seitsonen S, Immonen IJ, Häppölä P, Raychaudhuri S, Daly MJ, Seddon JM (2016). Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration† . Human molecular genetics.

Zhang Y, Wagner EK, Guo X, May I, Cai Q, Zheng W, He C, Long J (2016). Long intergenic non-coding RNA expression signature in human breast cancer . Scientific reports.

Wu W, Wagner EK, Hao Y, Rao X, Dai H, Han J, Chen J, Storniolo AMV, Liu Y, He C (2016). Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer . Scientific reports.

Wagner EK, Raychaudhuri S, Villalonga MB, Java A, Triebwasser MP, Daly MJ, Atkinson JP, Seddon JM (2016). Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD . Scientific reports.

Busby B, Lesko M, August 2015 and January 2016 Hackathon participants, Federer L (2016). Closing gaps between open software and public data in a hackathon setting: User-centered software prototyping . F1000Research.

Triebwasser MP, Roberson ED, Yu Y, Schramm EC, Wagner EK, Raychaudhuri S, Seddon JM, Atkinson JP (2015). Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration . Investigative ophthalmology & visual science.

Kavanagh D, Yu Y, Schramm EC, Triebwasser M, Wagner EK, Raychaudhuri S, Daly MJ, Atkinson JP, Seddon JM (2015). Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels . Human molecular genetics.

Tu W, Wagner EK, Eckert GJ, Yu Z, Hannon T, Pratt JH, He C (2014). Associations between menarche-related genetic variants and pubertal growth in male and female adolescents . The Journal of adolescent health : official publication of the Society for Adolescent Medicine.

Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, et al. (2014). Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche . Nature.