プロフィール詳細

プロジェクトを作成

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Dr. Ethiene C.に依頼

Brazil

Biomedical Scientist / Medical Writer / Scientific Consultant

プロフィール概要

I am a Biomedical Scientist with a multidisciplinary background. I hold a Master's and a Ph.D. in Pharmacology and have worked as a researcher for over 15 years. During my first Postdoc scholarship in Molecular Pharmacology, I conducted a project focused on the development of novel redox-modulating agents based on natural compounds with antimicrobial, nematicidal, and antitumor activities and an in-depth study of their activity and modes of action. In a second Postdoctoral fellowship in Oncology, I worked on the development of a PDX (Patient-Derived Xenografts) model platform and the establishment of primary tumoral cell lines that would enable the characterization of extracellular vesicles to identify biomarkers of prognosis and therapeutic response in patients affected by that disease. Recently I started a career in Clinical Research, designing and reviewing study protocols. I have extensive know-how in writing scientific projects, reports, papers, and abstracts. Experience in bibliographic search in scientific databases with the ability to perform critical analysis of scientific literature. I am a science enthusiast and a dedicated professional with strong organizational and technical skills. How can I help you today?

専門分野

• ☆ Drug Development
• ☆ Preclinical Pharmacology
• ☆ In vitro Diagnostics
• ☆ In vitro Diagnostic Validation
• ☆ Biomarker Analysis
• ☆ Clinical Trials
• ☆ IRB Applications
• ☆ Clinical Trial Design
• ☆ Human Biology
• ☆ Clinical Laboratory Science
• ☆ Clinical Pathology
• ☆ Clinical Biochemistry
• ☆ Regulatory Affairs
• ☆ Inflammation
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Carcinogenesis

サービス

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Business & Legal Writing, Newswriting, General Proofreading & Editing, Translation

Research Gap Analysis, Scientific and Technical Research, Secondary Data Collection

Consulting Go-to-Market Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting

職務経験

Clinical Research Analyst

Science Valley Research Institute

5月 2022 - 6月 2023

Postdoctoral Researcher

A C Camargo Cancer Center

5月 2017 - 3月 2021

Postdoctoral Researcher

Universitat des Saarlandes

11月 2013 - 10月 2015

Lecturer, Senior Lecturer

Santa Emília de Rodat College

8月 2008 - 10月 2012

Post graduate researcher

Federal University of Paraíba

2月 2006 - 2月 2012

Researcher Trainee

Federal University of Pernambuco

2月 2002 - 7月 2005

学歴

PhD (Natural and Synthetic Bioactive Products - Pharmacology)

Federal University of Paraíba

2月 2008 - 2月 2012

Masters in Natural and Synthetic Bioactive Products - Pharmacoloy

Federal University of Paraíba

2月 2006 - 2月 2008

Bachelors in Biomedicine

Ferderal University of Pernambuco

3月 2001 - 7月 2005

認定資格

• Specialist in Microbiology

  Brazilian Society of Microbiology

  12月 2011 - 現在

出版物

JOURNAL ARTICLE

Adriano O. Beserra, Ethiene C. Estevan, Stephania M. Bezerra, Giovana T. Torrezan, Amanda Ikegami, Humberto Dellê, Isabela W. Cunha, Isabella T. Meira, Dirce M. Carraro, Primo N. Lara, et al.(2022). Patient-Derived Renal Cell Carcinoma Xenografts Capture Tumor Genetic Profiles and Aggressive Behaviors . Kidney Cancer. 6. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11--22. {IOS} Press

Nassifatou Koko Tittikpina, Chukwunonso ECC Ejike, Ethiene Castelluci Estevam, Muhammad Jawad Nasim, Sharoon Griffin, Patrick Chaimbault, Gilbert Kirsch, Wouyo Atakpama, Komlan Batawila, Claus Jacob(2017). Togo to go: Products and compounds derived from local plants for the treatment of diseases endemic in Sub-Saharan Africa . African Journal of Traditional, Complementary and Alternative Medicines. 13. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 85. African Journals Online ({AJOL})

Estevam EC, Griffin S, Nasim MJ, Denezhkin P, Schneider R, Lilischkis R, Dominguez-Alvarez E, Witek K, Latacz G, Keck C, et al.(2016). Natural selenium particles from Staphylococcus carnosus: Hazards or particles with particular promise? . Journal of hazardous materials.

Ethiene C. Estevam, Lisa Faulstich, Sharoon Griffin, Torsten Burkholz, Claus Jacob(2015). Polysulfides in Biology: From Intricate Chemistry to an Astonishing Yet Hidden Biological Activity . Current Organic Chemistry. 20. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 211--217. Bentham Science Publishers Ltd.

Estevam EC, Griffin S, Nasim MJ, Zieliński D, Aszyk J, Osowicka M, Dawidowska N, Idroes R, Bartoszek A, Jacob C(2015). Inspired by Nature: The Use of Plant-derived Substrate/Enzyme Combinations to Generate Antimicrobial Activity in situ . Natural product communications.

Estevam EC, Witek K, Faulstich L, Nasim MJ, Latacz G, Domínguez-Álvarez E, Kieć-Kononowicz K, Demasi M, Handzlik J, Jacob C(2015). Aspects of a Distinct Cytotoxicity of Selenium Salts and Organic Selenides in Living Cells with Possible Implications for Drug Design . Molecules (Basel, Switzerland).

Mániková D, Letavayová LM, Vlasáková D, Košík P, Estevam EC, Nasim MJ, Gruhlke M, Slusarenko A, Burkholz T, Jacob C, et al.(2014). Intracellular diagnostics: hunting for the mode of action of redox-modulating selenium compounds in selected model systems . Molecules (Basel, Switzerland).

Ethiene Castellucci Estevam, Kelly Samara de Lira Mota, João Carlos Lima Rodrigues Pita, Viviane Marcelino Medeiros, Josean Fechine Tavares, Maria de Fátima Agra, Margareth de Fátima Formiga Melo Diniz, Marcelo Sobral da Silva, Leônia Maria Batista(2008). Evaluation of the toxicity and antiulcerogenic activity of the ethanol extract of Maytenus obtusifolia Mart. leaves . Revista Brasileira de Farmacognosia. 18. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 441--446. Springer Science and Business Media {LLC}

Estevam EC, Nakano E, Kawano T, de Bragança Pereira CA, Amancio FF, de Albuquerque Melo AM(2006). Dominant lethal effects of 2,4-D in Biomphalaria glabrata . Mutation research.

OTHER

Ethiene Castellucci Estevam, Muhammad Jawad Nasim, Lisa Faulstich, Marina Hakenesch, Torsten Burkholz, Claus Jacob(2015). A Historical Perspective on Oxidative Stress and Intracellular Redox Control . Oxidative Stress in Applied Basic Research and Clinical Practice. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3--20. Springer International Publishing