プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. fakher f.に依頼

Tunisia

Freelance Molecular modeling & Docking, Biostatistic, Data analyst & Experiment Design, Biochemistry

プロフィール概要

Freelance Molecular modeling & Docking ( MOE, Discovry, Autodock, ICM, MVD) +15 years of experience; Biostatistic, Data analyst & Experiment Design (JMP, Design-Expert) +15 years of experience;

専門分野

• ★ Molecular Modeling
• ★ Biostatistics
• ★ Biochemistry
• ☆ Molecular Docking
• ☆ Bioinformatics

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Technical Writing

Research Market Research, Feasibility Study

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

Product Development Formulation, Stability/Shelf Life Testing

職務経験

Maître assistant

Université de Sfax Faculté des Sciences de Sfax

2009 - 現在

学歴

(Génie biologique )

Ecole Nationale d'Ingénieurs de Sfax

- 現在

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Zribi Zghal, R., Frikha, F., Elleuch, J., Darriet, F., Chandre, F., Jaoua, S., Tounsi, S.(2019). The combinatory effect of Cyt1Aa flexibility and specificity against dipteran larvae improves the toxicity of Bacillus thuringensis kurstaki toxins . International Journal of Biological Macromolecules. 123. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 42-49.

Rekik, H., Frikha, F., Zaraî Jaouadi, N., Gargouri, F., Jmal, N., Bejar, S., Jaouadi, B.(2019). Gene cloning, expression, molecular modeling and docking study of the protease SAPRH from Bacillus safensis strain RH12 . International Journal of Biological Macromolecules. 125. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 876-891.

Rekik, H., Zaraî Jaouadi, N., Gargouri, F., Bejar, W., Frikha, F., Jmal, N., Bejar, S., Jaouadi, B.(2019). Production, purification and biochemical characterization of a novel detergent-stable serine alkaline protease from Bacillus safensis strain RH12 . International Journal of Biological Macromolecules. 121. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1227-1239.

Frikha, R., Rebai, T., Lobna, B.M., Frikha, F., Mdhaffar, M., Frikha, I., Elloumi, M., Bouayed, N.(2018). Comprehensive analysis of Methylenetetrahydrofolate reductase C677T in younger acute lymphoblastic leukemia patients: A single-center experience . Journal of Oncology Pharmacy Practice.

Jallouli, W., Boukedi, H., Sellami, S., Frikha, F., Abdelkefi-Mesrati, L., Tounsi, S.(2018). Combinatorial effect of Photorhabdus luminescens TT01 and Bacillus thuringiensis Vip3Aa16 toxin against Agrotis segetum . Toxicon. 142. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 52-57.

Sellami, M., Frikha, F., Aribi, A., Taktak, I., Miled, N., Rebah, F.B.(2018). Optimization of wastewater based media for biopolymers production by rhizobium leguminosarum . Environmental Engineering and Management Journal. 17. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1329-1335.

Daâssi, D., Zouari-Mechichi, H., Frikha, F., Rodríguez-Couto, S., Nasri, M., Mechichi, T.(2016). Sawdust waste as a low-cost support-substrate for laccases production and adsorbent for azo dyes decolorization . Journal of Environmental Health Science and Engineering. 14. (1).

Daâssi, D., Sellami, S., Frikha, F., Rodriguez-Couto, S., Nasri, M., Mechichi, T.(2016). Assessment of Coriolopsis gallica-treated olive mill wastewater phytotoxicity on tomato plants . Environmental Science and Pollution Research. 23. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 15370-15380.

Arous, F., Frikha, F., Triantaphyllidou, I.-E., Aggelis, G., Nasri, M., Mechichi, T.(2016). Potential utilization of agro-industrial wastewaters for lipid production by the oleaginous yeast Debaryomyces etchellsii . Journal of Cleaner Production. 133. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 899-909.

Sila, A., Alvarez, O.M., Haddar, A., Frikha, F., Dhulster, P., Nedjar-Arroume, N., Bougatef, A.(2016). Purification, identification and structural modelling of DPP-IV inhibiting peptides from barbel protein hydrolysate . Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1008. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 260-269.

Ghazala, I., Sila, A., Frikha, F., Driss, D., Ellouz-Chaabouni, S., Haddar, A.(2015). Antioxidant and antimicrobial properties of water soluble polysaccharide extracted from carrot peels by-products . Journal of Food Science and Technology. 52. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6953-6965.

Hadiji-Abbes, N., Mihoubi, W., Martin, M., Karakasyan-Dia, C., Frikha, F., Gergely, C., Jouenne, T., Gargouri, A., Mokdad-Gargouri, R.(2015). Characterization of C69R variant HBsAg: effect on binding to anti-HBs and the structure of virus-like particles . Archives of Virology. 160. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2427-2433.

Fendri, A., Frikha, F., Louati, H., Ali, M.B., Gargouri, H., Gargouri, Y., Miled, N.(2015). Cloning and molecular modeling of a thermostable carboxylesterase from the chicken uropygial glands . Journal of Molecular Graphics and Modelling. 56. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1-9.

Aloulou, A., Frikha, F., Noiriel, A., Bou Ali, M., Abousalham, A.(2014). Kinetic and structural characterization of triacylglycerol lipases possessing phospholipase A<inf>1</inf> activity . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1841. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 581-587.

Benzina, O., Da&#226;ssi, D., Zouari-Mechichi, H., Frikha, F., Woodward, S., Belbahri, L., Rodriguez-Couto, S., Mechichi, T.(2013). Decolorization and detoxification of two textile industry effluents by the laccase/1-hydroxybenzotriazole system . Environmental Science and Pollution Research. 20. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5177-5187.

Kilani-Feki, O., Frikha, F., Zouari, I., Jaoua, S.(2013). Heterologous expression and secretion of an antifungal Bacillus subtilis chitosanase (CSNV26) in Escherichia coli . Bioprocess and Biosystems Engineering. 36. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 985-992.

Sellami, M., Kedachi, S., Frikha, F., Miled, N., Ben Rebah, F.(2013). Optimization of marine waste based-growth media for microbial lipase production using mixture design methodology . Environmental Technology (United Kingdom). 34. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2259-2266.

Chaari, A., Horchani, H., Frikha, F., Verger, R., Gargouri, Y., Ladjimi, M.(2013). Surface behavior of α-Synuclein and its interaction with phospholipids using the Langmuir monolayer technique: A comparison between monomeric and fibrillar α-Synuclein . International Journal of Biological Macromolecules. 58. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 190-198.

Haddar, A., Driss, D., Frikha, F., Ellouz-Chaabouni, S., Nasri, M.(2012). Alkaline xylanases from Bacillus mojavensis A21: Production and generation of xylooligosaccharides . International Journal of Biological Macromolecules. 51. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 647-656.

Da&#226;ssi, D., Frikha, F., Zouari-Mechichi, H., Belbahri, L., Woodward, S., Mechichi, T.(2012). Application of response surface methodology to optimize decolourization of dyes by the laccase-mediator system . Journal of Environmental Management. 108. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 84-91.

Ouertani, S., Frikha, F., Horchani, H., Ben Salem, N., Gargouri, Y., Sayari, A.(2012). The insertion of four residues Isoleucines at the N-terminus of Staphylococcus simulans lipase affects its catalytic and biochemical properties . Journal of Molecular Catalysis B: Enzymatic. 82. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1-7.

Sellami, M., Ghamgui, H., Frikha, F., Gargouri, Y., Miled, N.(2012). Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat . BMC Biotechnology. 12.

Romdhane, I.B.B., Frikha, F., Maalej-Achouri, I., Gargouri, A., Belghith, H.(2012). Gene cloning and molecular characterization of the Talaromyces thermophilus lipase Catalyzed efficient hydrolysis and synthesis of esters . Gene. 494. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 112-118.

Aissa, I., Leclaire, J., Ali, Y.B., Frikha, F., Gargouri, Y.(2012). Monolayer properties of synthesized tyrosyl esters . Journal of Molecular Catalysis B: Enzymatic. 83. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 125-130.

Sellami, M., Frikha, F., Aissa, I., Gargouri, Y., Miled, N.(2012). Production of fatty acids, monoacylglycerols and diacylglycerols by hydrolysis of palm olein using immobilized turkey pancreatic lipase . Current Chemical Biology. 6. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 104-112.

Siala, R., Frikha, F., Mhamdi, S., Nasri, M., Sellami Kamoun, A.(2012). Optimization of acid protease production by Aspergillus niger I1 on shrimp peptone using statistical experimental design . The Scientific World Journal. 2012.

Romdhan, I.B.-B., Fendri, A., Frikha, F., Gargouri, A., Belghith, H.(2012). Purification, physico-chemical and kinetic properties of the deglycosylated Talaromyces thermophilus lipase . International Journal of Biological Macromolecules. 51. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 892-900.

Aissa, I., Bouaziz, M., Frikha, F., Mansour, R.B., Gargouri, Y.(2012). Synthesized tyrosyl hydroxyphenylacetate, a novel antioxidant, anti-stress and antibacterial compound . Process Biochemistry. 47. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2356-2364.

Zouari, N., Ayadi, M.A., Hadj-Taieb, S., Frikha, F., Attia, H.(2012). Whey powder, ι -carrageenan, and fat interactions and their influence on instrumental texture and sensory properties of Turkey meat sausage using a mixture design approach . International Journal of Food Properties. 15. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1233-1246.

Frikha, F., Kammoun, M., Hammami, N., Mchirgui, R.A., Belbahri, L., Gargouri, Y., Miled, N., Ben-Rebah, F.(2011). Chemical composition and some biological activities of marine algae collected in Tunisia,Composición química y algunas actividades biológicas de algas marinas recolectadas en túnez . Ciencias Marinas. 37. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 113-124.

Eslami, G., Frikha, F., Salehi, R., Khamesipour, A., Hejazi, H., Nilforoushzadeh, M.A.(2011). Cloning, expression and dynamic simulation of TRYP6 from Leishmania major (MRHO/IR/75/ER) . Molecular Biology Reports. 38. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3765-3776.

Sellami, M., Aissa, I., Frikha, F., Gargouri, Y., Miled, N.(2011). Immobilized Rhizopus oryzae lipase catalyzed synthesis of palm stearin and cetyl alcohol wax esters: Optimization by Response Surface Methodology . BMC Biotechnology. 11.

Zarai, Z., Frikha, F., Balti, R., Miled, N., Gargouri, Y., Mejdoub, H.(2011). Nutrient composition of the marine snail (Hexaplex trunculus) from the Tunisian Mediterranean coasts . Journal of the Science of Food and Agriculture. 91. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1265-1270.

Karray, A., Frikha, F., Ben Ali, Y., Gargouri, Y., Bezzine, S.(2011). Purification and biochemical characterization of a secreted group IIA chicken intestinal phospholipase A<inf>2</inf> . Lipids in Health and Disease. 10.

Kacem, M., Sellami, M., Kammoun, W., Frikha, F., Miled, N., Ben Rebah, F.(2011). Seasonal variations in proximate and fatty acid composition of viscera of sardinella aurita, sarpa salpa, and sepia officinalis from Tunisia . Journal of Aquatic Food Product Technology. 20. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 233-246.

Fakhfakh-Zouari, N., Haddar, A., Hmidet, N., Frikha, F., Nasri, M.(2010). Application of statistical experimental design for optimization of keratinases production by Bacillus pumilus A1 grown on chicken feather and some biochemical properties . Process Biochemistry. 45. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 617-626.

Frikha, F., Miled, N., Bacha, A.B., Mejdoub, H., Gargouri, Y.(2010). Structural homologies, importance for catalysis and lipid binding of the N-terminal peptide of a fungal and a pancreatic lipase . Protein and Peptide Letters. 17. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 254-259.

Choura, M., Frikha, F., Kharrat, N., Aifa, S., Reba&#239;, A.(2010). Investigating the function of three non-synonymous SNPs in EGFR gene: Structural modelling and association with breast cancer . Protein Journal. 29. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 50-54.

Haddar, A., Fakhfakh-Zouari, N., Hmidet, N., Frikha, F., Nasri, M., Kamoun, A.S.(2010). Low-cost fermentation medium for alkaline protease production by Bacillus mojavensis A21 using hulled grain of wheat and sardinella peptone . Journal of Bioscience and Bioengineering. 110. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 288-294.

Karray, A., Frikha, F., Ben Bacha, A., Ben Ali, Y., Gargouri, Y., Bezzine, S.(2009). Biochemical and molecular characterization of purified chicken pancreatic phospholipase A <inf>2</inf> . FEBS Journal. 276. (16). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4545-4554.

Agrebi, R., Haddar, A., Hajji, M., Frikha, F., Manni, L., Jellouli, K., Nasri, M.(2009). Fibrinolytic enzymes from a newly isolated marine bacterium Bacillus subtilis A26: Characterization and statistical media optimization . Canadian Journal of Microbiology. 55. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1049-1061.

Frikha, F., Ladjimi, M., Gargouri, Y., Miled, N.(2008). 3-D structure modelling of the Staphylococcus simulans lipase: Conformational changes, substrate specificity and novel structural features . FEMS Microbiology Letters. 286. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 207-221.

Cherif, S., Frikha, F., Gargouri, Y., Miled, N.(2008). Fatty acid composition of green crab (Carcinus mediterraneus) from the Tunisian mediterranean coasts . Food Chemistry. 111. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 930-933.

Ben Rebah, F., Smaoui, S., Frikha, F., Gargouri, Y., Miled, N.(2008). Inhibitory effects of tunisian marine algal extracts on digestive lipases . Applied Biochemistry and Biotechnology. 151. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 71-79.

Rebah, F.B., Frikha, F., Kamoun, W., Belbahri, L., Gargouri, Y., Miled, N.(2008). Culture of Staphylococcus xylosus in fish processing by-product-based media for lipase production . Letters in Applied Microbiology. 47. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 549-554.

Fendri, A., Frikha, F., Miled, N., Ben Bacha, A., Gargouri, Y.(2007). Modulating the activity of avian pancreatic lipases by an alkyl chain reacting with an accessible sulfhydryl group . Biochemical and Biophysical Research Communications. 360. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 765-771.

Bacha, A.B., Frikha, F., Djemal, I., Fendri, A., Miled, N., Gargouri, Y., Mejdoub, H.(2006). Biochemical and structural comparative study between bird and mammal pancreatic colipases . Journal of Lipid Research. 47. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2701-2711.

Fendri, A., Frikha, F., Mosbah, H., Miled, N., Zouari, N., Bacha, A.B., Sayari, A., Mejdoub, H., Gargouri, Y.(2006). Biochemical characterization, cloning, and molecular modelling of chicken pancreatic lipase . Archives of Biochemistry and Biophysics. 451. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 149-159.

Fendri, A., Frikha, F., Miled, N., Gargouri, Y.(2006). Cloning and molecular modelling of turkey pancreatic lipase: structural explanation of the increased interaction power with lipidic interface . Biochimie. 88. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1401-1407.

Aifa, S., Miled, N., Frikha, F., Aniba, M.R., Svensson, S.P.S., Rebai, A.(2006). Electrostatic interactions of peptides flanking the tyrosine kinase domain in the epidermal growth factor receptor provides a model for intracellular dimerization and autophosphorylation . Proteins: Structure, Function and Genetics. 62. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1036-1043.

Aifa, S., Frikha, F., Miled, N., Johansen, K., Lundstr&#246;m, I., Svensson, S.P.S.(2006). Phosphorylation of Thr⁶⁵⁴ but not Thr⁶⁶⁹ within the juxtamembrane domain of the EGF receptor inhibits calmodulin binding . Biochemical and Biophysical Research Communications. 347. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 381-387.

Sayari, A., Frikha, F., Miled, N., Mtibaa, H., Ali, Y.B., Verger, R., Gargouri, Y.(2005). N-terminal peptide of Rhizopus oryzae lipase is important for its catalytic properties . FEBS Letters. 579. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 976-982.