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プロフィール詳細
プロジェクトを作成
★★★★★
☆☆☆☆☆
Dr. Fanny L.に依頼
United States

PhD Immunology | Pharmacy | Scientific communicator 11 yrs of experience in biomedical research | Analyst |

プロフィール概要
専門分野
サービス
Writing Clinical Trial Documentation, Technical Writing
Research Feasibility Study, Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection
Consulting Scientific and Technical Consulting
Data & AI Statistical Analysis, Data Processing, Data Insights
職務経験

Consultant

Planet Pharma LLC

6月 2022 - 現在

Research Fellow

National Institutes of Health

10月 2016 - 10月 2019

Post-doctoral Fellow

National Institutes of Health

10月 2011 - 10月 2016

Research and Teaching Assistant

Université du Droit et la Santé de Lille 2 - Faculté de Médecine Henri-Warembourg

11月 2009 - 11月 2011

Intern in Pharmacy and Biology

Centre Hospitalier Regional et Universitaire de Lille

2008 - 2009

Research and Teaching Assistant

Université de Lille II Faculté des Sciences Pharmaceutiques et Biologiques

2006 - 2008

学歴

Pharm D (Immunology)

Université de Lille II Faculté des Sciences Pharmaceutiques et Biologiques

9月 1998 - 10月 2009

Ph.D. Immunology (EDBSL)

Université Lille 2 Droit et Santé

11月 2005 - 11月 2008

Research Master (Pharmacy)

Université de Lille II Faculté des Sciences Pharmaceutiques et Biologiques

10月 2003 - 10月 2004

認定資格
  • Intellectual Property for Entrepreneurs

    Coursera online non-credit course - University of Maryland, College Park, US
    https://coursera.org/share/9b03b2a42660e6a1bdbccc80b928fb46

    1月 2022 - 現在

  • Qualification in teaching Cellular Biology and Biological, Fundamental and Clinical Sciences

    National University Council, Paris, France

    1月 2011 - 1月 2021

出版物
PREPRINT
Andrea C. Bohrer and Ehydel Castro and Claire E. Tocheny and Maike Assmann and Benjamin Schwarz and Eric Bohrnsen and Michelle A. Makiya and Fanny Legrand and Kerry L. Hilligan and Paul J. Baker and Flor Torres-Juarez and Zhidong Hu and Hui Ma and Lin Wang and Liangfei Niu and Wen Zilu and Sang H. Lee and Olena Kamenyeva and Keith D. Kauffman and Michele Donato and Alan Sher and Daniel L. Barber and Laura E. Via and Thomas J. Scriba and Purvesh Khatri and Yanzheng Song and Ka-Wing Wong and Catharine M. Bosio and Amy D. Klion and Katrin D. Mayer-Barber and(2022). Rapid GPR183-mediated recruitment of eosinophils to the lung after <i>Mycobacterium tuberculosis</i> infection . []. Cold Spring Harbor Laboratory
JOURNAL ARTICLE
Fanny Legrand(2021). Legends of allergy and immunology: Monique Capron . Allergy. 76. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 937--939. Wiley
(2021). Eosinophil Purification from Peripheral Blood of Rhesus Monkeys . Methods in molecular biology (Clifton, N.J.).
Fanny Legrand, So Gun Hong, Noriko Sato, Manasi Gadkari, Michelle Makiya, Kindra Stokes, Katherine N. Howe, Shiqin Judy Yu, Nathaniel Seth Linde, Randall R. Clevenger, et al. (2020). Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration . Blood.
Fanny Legrand, Nadine Landolina, Ilan Zaffran, Robert O. Emeh, Elizabeth Chen, Amy D. Klion, Francesca Levi-Schaffer(2019). Siglec-7 on peripheral blood eosinophils: Surface expression and function . Allergy. Wiley
(2019). Benralizumab for PDGFRA-Negative Hypereosinophilic Syndrome . The New England journal of medicine.
Legrand, F., Cao, Y., Wechsler, J.B., Zhu, X., Zimmermann, N., Rampertaap, S., Monsale, J., Romito, K., Youngblood, B.A., Brock, E.C., et al.(2019). Sialic acid–binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies . Journal of Allergy and Clinical Immunology. 143. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2227-2237.e10.
Kuang, F.L., Legrand, F., Makiya, M., Ware, J.A., Wetzler, L., Brown, T., Magee, T., Piligian, B., Yoon, P., Ellis, J.H., et al.(2019). Benralizumab for PDGFRA-negative hypereosinophilic syndrome . New England Journal of Medicine. 380. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1336-1346.
Legrand, F., Landolina, N., Zaffran, I., Emeh, R.O., Chen, E., Klion, A.D., Levi-Schaffer, F.(2019). Siglec-7 on peripheral blood eosinophils: Surface expression and function . Allergy: European Journal of Allergy and Clinical Immunology. 74. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1257-1265.
P. Khoury, K. Stokes, M. Gadkari, M. A. Makiya, F. Legrand, Z. Hu, A. Klion, L. M. Franco(2018). Glucocorticoid‐induced eosinopenia in humans can be linked to early transcriptional events . Allergy. 73. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2076--2079. Wiley
Gadkari, M., Makiya, M.A., Legrand, F., Stokes, K., Brown, T., Howe, K., Khoury, P., Hu, Z., Klion, A., Franco, L.M.(2018). Data descriptor: Transcript-and protein-level analyses of the response of human eosinophils to glucocorticoids . Scientific Data. 5.
Khoury, P., Stokes, K., Gadkari, M., Makiya, M.A., Legrand, F., Hu, Z., Klion, A., Franco, L.M.(2018). Glucocorticoid-induced eosinopenia in humans can be linked to early transcriptional events . Allergy: European Journal of Allergy and Clinical Immunology. 73. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2076-2079.
Legrand, Fanny, Herrick, Jesica A., Gounoue, Raceline, Nchinda, Godwin, Montavon, Celine, Bopda, Jean, Tchana, Steve Mbickmen, Ondigui, Bienvenu Etogo, Nguluwe, Konrad, Fay, Michael P., et al.(2017). Posttreatment Reactions After Single-Dose Diethylcarbamazine or Ivermectin in Subjects With Loa loa Infection . Clinical Infectious Diseases. 64. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1017-1025.
Legrand, Fanny, Landolina, Nadine A., Levi-Schaffer, Francesca, Klion, Amy D.(2016). Siglec-7 on Peripheral Blood Eosinophils: Surface Expression and Functional Analysis . Journal of Allergy and Clinical Immunology. 137. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString AB167.
Legrand, Fanny and Landolina, Nadine A. and Levi-Schaffer, Francesca and Klion, Amy D.(2016). Siglec-7 on Peripheral Blood Eosinophils: Surface Expression and Functional Analysis . Journal of Allergy and Clinical Immunology. 137. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString AB167.
Legrand, Fanny, Klion, Amy D.(2015). Biologic Therapies Targeting Eosinophils: Current Status and Future Prospects . Journal of Allergy and Clinical Immunology-in Practice. 3. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 167-174.
Legrand, Fanny, Alpaugh, Alexandra, Falahati, Rustom, Makiya, Michelle, Klion, Amy D.(2015). A Novel Therapeutic Target for the Treatment of Eosinophilic Disorders . Journal of Allergy and Clinical Immunology. 135. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString AB221.
Legrand, F., Klion, A.D.(2015). Biologic Therapies Targeting Eosinophils: Current Status and Future Prospects . Journal of Allergy and Clinical Immunology: In Practice. 3. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 167-174.
Lef&#232;vre, G., Copin, M.-C., Staumont-Sall&#233;, D., Avenel-Audran, M., Aubert, H., Taieb, A., Salles, G., Maisonneuve, H., Ghomari, K., Ackerman, F., et al.(2014). The lymphoid variant of hypereosinophilic syndrome study of 21 patients with CD3-CD4+ aberrant T-cell phenotype . Medicine (United States). 93. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 255-266.
Legrand, Fanny, Tomasevic, Nenad, Simakova, Olga, Lee, Chyi-Chia Richard, Wang, Zengfang, Raffeld, Mark, Makiya, Michelle A., Palath, Varghese, Leung, John, Baer, Mark, et al.(2014). The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders . Journal of Allergy and Clinical Immunology. 133. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1439-U350.
Legrand, Fanny, Lefevre, Guillaume, Copin, Marie-Christine, Staumont-Salle, Delphine, Avenel-Audran, Martine, Aubert, Helene, Taieb, Alain, Salles, Gilles, Maisonneuve, Herve, Ghomari, Kamel, et al.(2014). The Lymphoid Variant of Hypereosinophilic Syndrome Study of 21 Patients With CD3-CD4+ Aberrant T-Cell Phenotype . Medicine. 93. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 255-266.
Legrand, Fanny, Tomasevic, Nenad, Makiya, Michelle, Bebbington, Christopher, Klion, Amy D.(2014). Human EMR1, An Eosinophil-Specific Surface Receptor Of Unknown Function, Is Modulated In Vivo and In Vitro . Journal of Allergy and Clinical Immunology. 133. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString AB61.
Legrand, F., Tomasevic, N., Simakova, O., Lee, C.-C.R., Wang, Z., Raffeld, M., Makiya, M.A., Palath, V., Leung, J., Baer, M., et al.(2014). The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders . Journal of Allergy and Clinical Immunology. 133. (5).
Legrand, Fanny, Driss, Virginie, Capron, Monique(2013). Eosinophil Receptor Profile . Eosinophils in Health and Disease. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 30-38.
Legrand, Fanny, Grainger, John R., Wohlfert, Elizabeth A., Fuss, Ivan J., Bouladoux, Nicolas, Askenase, Michael H., Koo, Lily Y., Brenchley, Jason M., Fraser, Iain D. C., Belkaid, Yasmine(2013). Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection . Nature Medicine. 19. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 713-+.
Legrand, Fanny, Renneville, Aline, MacIntyre, Elizabeth, Mastrilli, Samuel, Ackermann, Felix, Cayuela, Jean Michel, Rousselot, Philippe, Schmidt-Tanguy, Aline, Fain, Olivier, Michel, Marc, et al.(2013). The Spectrum of FIP1L1-PDGFRA-Associated Chronic Eosinophilic Leukemia New Insights Based on a Survey of 44 Cases . Medicine. 92. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E1-E9.
Grainger, J.R., Wohlfert, E.A., Fuss, I.J., Bouladoux, N., Askenase, M.H., Legrand, F., Koo, L.Y., Brenchley, J.M., Fraser, I.D.C., Belkaid, Y.(2013). Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection . Nature Medicine. 19. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 713-721.
Legrand, F., Renneville, A., MacIntyre, E., Mastrilli, S., Ackermann, F., Cayuela, J.M., Rousselot, P., Schmidt-Tanguy, A., Fain, O., Michel, M., et al.(2013). The spectrum of FIP1L1-PDGFRA-associated chronic eosinophilic leukemia: New insights based on a survey of 44 cases . Medicine (United States). 92. (5).
Driss, V., Hermann, E., Legrand, F., Loiseau, S., Delbeke, M., Kremer, L., Guerardel, Y., Dombrowicz, D., Capron, M.(2012). CR3-dependent negative regulation of human eosinophils by Mycobacterium bovis BCG lipoarabinomannan . Immunology Letters. 143. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 202-207.
Legrand, Fanny, Driss, Virginie, Hermann, Emmanuel, Loiseau, Sylvie, Delbeke, Marie, Kremer, Laurent, Guerardel, Yann, Dombrowicz, David, Capron, Monique(2012). CR3-dependent negative regulation of human eosinophils by Mycobacterium bovis BCG lipoarabinomannan . Immunology Letters. 143. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 202-207.
Kahn, J.-E., Lef&#232;vre, G., Legrand, F.(2012). Hypereosinophilia,Hyperéosinophilies . Feuillets de Biologie. 53. (305). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5-12.
Gatault, S., Legrand, F., Delbeke, M., Loiseau, S., Capron, M.(2012). Involvement of eosinophils in the anti-tumor response . Cancer Immunology, Immunotherapy. 61. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1527-1534.
Gatault, Solene, Delbeke, Marie, Loiseau, Sylvie, Capron, Monique, Legrand, Fanny(2012). Involvement of eosinophils in the anti-tumor response . Cancer Immunology Immunotherapy. 61. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1527-1534.
Kahn, J.-E., Schoindre, Y., Legrand, F., Bletry, O., Ackermann, F.(2011). Unexplained chronic hypereosinophilia and hypereosinophilic syndrome,Hyperéosinophilies chroniques inexpliquées et syndromes hyperéosinophiliques . Revue des Maladies Respiratoires Actualites. 3. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 108-113.
Freymond, N., Kahn, J.-E., Legrand, F., Renneville, A., Cordier, J.-F., Cottin, V.(2011). Clonal expansion of T cells in patients with eosinophilic lung disease . Allergy: European Journal of Allergy and Clinical Immunology. 66. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1506-1508.
Kahn, J.-E., Ackermann, F., Prin, L., Capron, M., Legrand, F., Bletry, O.(2011). The eosinophil: From physiology to diagnostic procedure,L'éosinophile: de la physiologieà la démarche diagnostique . Revue des Maladies Respiratoires Actualites. 3. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 102-107.
Legrand, F., Driss, V., Delbeke, M., Loiseau, S., Hermann, E., Dombrowicz, D., Capron, M.(2010). Human Eosinophils Exert TNF-alpha and Granzyme A-Mediated Tumoricidal Activity toward Colon Carcinoma Cells . Journal of Immunology. 185. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7443-7451.
Kahn, J. E., Grandpeix-Guyodo, C., Ackermann, F., Charles, P., Legrand, F., Bletry, O.(2010). Hypereosinophilic syndromes: Pathogenic and therapeutic up-to-date . Revue De Medecine Interne. 31. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 268-276.
Legrand, F., Driss, V., Delbeke, M., Loiseau, S., Hermann, E., Dombrowicz, D., Capron, M.(2010). Human eosinophils exert TNF-α and granzyme a-mediated tumoricidal activity toward colon carcinoma cells . Journal of Immunology. 185. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7443-7451.
Kahn, J.-E., Grandpeix-Guyodo, C., Ackermann, F., Charles, P., Legrand, F., Bl&#233;try, O.(2010). Hypereosinophilic syndromes: Pathogenic and therapeutic up-to-date,Syndromes hyperéosinophiliques: Actualités physiopathologiques et thérapeutiques . Revue de Medecine Interne. 31. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 268-276.
Bletry, O., Kahn, J. E., Ackermann, F., Charles, P., Legrand, F.(2010). New insights into hypereosinophilic syndromes . Bulletin De L Academie Nationale De Medecine. 194. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 547-559.
Driss, V., Legrand, F., Loiseau, S., Capron, M.(2010). Eosinophil: A new effector of innate immunity?,L'eosinophile: Nouvel acteur de la réponse immunitaire innée? . Medecine/Sciences. 26. (6-7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 621-626.
Driss, V., Legrand, F., Loiseau, S., Capron, M.(2010). Eosinophil: a new effector of innate immunity? . M S-Medecine Sciences. 26. (6-7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 621-626.
Bletry, O., Kahn, J.-E., Ackermann, F., Charles, P., Legrand, F.(2010). New insights into hypereosinophilic syndromes,À la redécouverte des syndromes hyperéosinophiliques . Bulletin de l'Academie Nationale de Medecine. 194. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 547-560.
Kanda, A., Driss, V., Hornez, N., Abdallah, M., Roumier, T., Abboud, G., Legrand, F., Staumont-Salle, D., Queant, S., Bertout, J., et al.(2009). Eosinophil-derived IFN-gamma induces airway hyperresponsiveness and lung inflammation in the absence of lymphocytes . Journal of Allergy and Clinical Immunology. 124. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 573-U269.
Kanda, A., Driss, V., Hornez, N., Abdallah, M., Roumier, T., Abboud, G., Legrand, F., Staumont-Sall&#233;, D., Qu&#233;ant, S., Bertout, J., et al.(2009). Eosinophil-derived IFN-γ induces airway hyperresponsiveness and lung inflammation in the absence of lymphocytes . Journal of Allergy and Clinical Immunology. 124. (3).
Capron, M., Legrand, F.(2009). Functions of eosinophil granulocytes: ffrom anti-parasite immunity to anti-tumoral potential,Fonctions des polynucléaires éosinophiles: de I'immunité anti-parasitaire aux potentialités anti tumorales . Bulletin de l'Academie Nationale de Medecine. 193. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 339-349.
Driss, V., Legrand, F., Hermann, E., Loiseau, S., Guerardel, Y., Kremer, L., Adam, E., Woerly, G., Dombrowicz, D., Capron, M.(2009). TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins . Blood. 113. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3235-3244.
Capron, M., Legrand, F.(2009). Functions of eosinophil granulocytes: from anti-parasite immunity to anti-tumoral potential . Bulletin De L Academie Nationale De Medecine. 193. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 339-346.
Legrand, F., Driss, V., Woerly, G., Loiseau, S., Hermann, E., Fournie, J. J., Heliot, L., Mattot, V., Soncin, F., Gougeon, M. L., et al.(2009). A Functional gamma delta TCR/CD3 Complex Distinct from gamma delta T Cells Is Expressed by Human Eosinophils . Plos One. 4. (6).
Legrand, F., Driss, V., Woerly, G., Loiseau, S., Hermann, E., Fourni&#233;, J.-J., H&#233;liot, L., Mattot, V., Soncin, F., Gougeon, M.-L., et al.(2009). A functional γδTCR/CD3 complex distinct from γδT cells is expressed by human eosinophils . PLoS ONE. 4. (6).
Driss, V., Legrand, F., Hermann, E., Loiseau, S., Guerardel, Y., Kremer, L., Adam, E., Woerly, G., Dombrowicz, D., Capron, M.(2009). TLR2-dependent eosinophil interactions with mycobacteria: Role of α-defensins . Blood. 113. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3235-3244.
(2008). Innate immune function of eosinophils: from antiparasite to antitumor cells . Methods in molecular biology (Clifton, N.J.).
Jensen-Jarolim, E., Achatz, G., Turner, M. C., Karagiannis, S., Legrand, F., Capron, M., Penichet, M. L., Rodriguez, J. A., Siccardi, A. G., Vangelista, L., et al.(2008). AllergoOncology: the role of IgE-mediated allergy in cancer . Allergy. 63. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1255-1266.
Jensen-Jarolim, E., Achatz, G., Turner, M.C., Karagiannis, S., Legrand, F., Capron, M., Penichet, M.L., Rodr&#237;guez, J.A., Siccardi, A.G., Vangelista, L., et al.(2008). AllergoOncology: The role of IgE-mediated allergy in cancer . Allergy: European Journal of Allergy and Clinical Immunology. 63. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1255-1266.
Legrand, F., Woerly, G., Driss, V., Capron, M.(2008). Innate immune function of eosinophils: from antiparasite to antitumor cells . Methods in molecular biology (Clifton, N.J.). 415. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 215-240.
(2007). Peau et éosinophilie . EMC - Dermatologie.
BOOK CHAPTER
Weller, P.F., Melo, R.C.N., Dvorak, A.M., Driss, V., Legrand, F., Capron, M.(2013). Eosinophil Structure and Cell Surface Receptors . Eosinophils in Health and Disease. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 19-38.