プロフィール詳細

プロジェクトを作成

★★★★★

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Dr. Federica L.に依頼

Italy

Researcher at University of Rome "Tor Vergata"

プロフィール概要

I am an immunologist with over 20 years of experience in biomedical research and more than 70 peer-reviewed publications in high-impact international journals. My expertise spans cancer immunology, colorectal cancer, inflammatory bowel disease (IBD), mucosal immunology, mitochondrial biology, and translational research. I currently work as a researcher at the University of Rome Tor Vergata and serve as Academic Editor and reviewer for several international journals. I help researchers, biotech companies, and clinicians transform scientific ideas into high-quality manuscripts, competitive grant applications, and robust experimental strategies. Services include: • Scientific manuscript editing • Manuscript review before journal submission • Grant proposal writing and editing • Reviewer response preparation • Experimental design • Data interpretation (RNA-seq, proteomics, metabolomics, flow cytometry) • Figure improvement and scientific storytelling • Literature reviews • Consultation in immunology, oncology and gastrointestinal diseases I combine scientific rigor with clear communication and practical solutions to help clients publish stronger papers and develop competitive research projects.

専門分野

• ★ Biology/Life Sciences
• ☆ Microbiology
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Allergy & Clinical Immunology
• ☆ Medical Sciences
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Research Methodology
• ☆ Technical & Scientific Writing

サービス

• Writing
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Creative Writing, Audio Transcription, General Proofreading & Editing, Translation

職務経験

Researcher

Università degli Studi di Roma Tor Vergata Facoltà di Medicina e Chirurgia

1月 2015 - 現在

Post-Doc

Charité Universitätsmedizin Berlin

2月 2014 - 1月 2015

Post-Doc

Singapore Immunology Network

1月 2011 - 1月 2014

学歴

PhD in Immunological Sciences

Università degli Studi di Roma La Sapienza

10月 2007 - 12月 2010

Academic degree in Molecular and Cellular Biology

Universita degli Studi di Roma Tor Vergata

10月 2002 - 7月 2007

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Federica Laudisi, Lorenzo Tomassini, Teresa Pacifico, Giovanni Monteleone, Carmine Stolfi (2026). From Gut Homeostasis to Colorectal Cancer: Spatial and Temporal Reprogramming of Microbial Inosine Signaling . Biomedicines.

Federica Laudisi, Lorenzo Tomassini, Teresa Pacifico, Giovanni Monteleone, Carmine Stolfi (2026). From Gut Homeostasis to Colorectal Cancer: Spatial and Temporal Reprogramming of Microbial Inosine Signaling . Biomedicines.

Federica Laudisi, Rachele Frascatani, Carmine Stolfi, Giovanni Monteleone (2026). Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer . Cancers.

Federica Laudisi, Rachele Frascatani, Carmine Stolfi, Giovanni Monteleone (2026). Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer . Cancers.

Federica Laudisi, Lorenzo Tomassini, Teresa Pacifico, Giovanni Monteleone, Carmine Stolfi (2025). Targeting Cancer Cell Energy Metabolism in Colorectal Cancer: Opportunities and Challenges from Drug Repositioning . Cells.

Federica Laudisi, Lorenzo Tomassini, Teresa Pacifico, Giovanni Monteleone, Carmine Stolfi (2025). Targeting Cancer Cell Energy Metabolism in Colorectal Cancer: Opportunities and Challenges from Drug Repositioning . Cells.

Federica Laudisi, Teresa Pacifico, Lorenzo Tomassini, Livia Biancone, Giovanni Monteleone, Carmine Stolfi (2025). Repurposing Rafoxanide: From Parasite Killer to Cancer Fighter . Biomedicines.

Federica Laudisi, Teresa Pacifico, Lorenzo Tomassini, Livia Biancone, Giovanni Monteleone, Carmine Stolfi (2025). Repurposing Rafoxanide: From Parasite Killer to Cancer Fighter . Biomedicines.

Federica Laudisi, Eleonora Franzè, Rachele Frascatani, Lorenzo Tomassini, Elena De Cristofaro, Carmine Stolfi, Giovanni Monteleone (2024). Bromodomain-Containing 4 Is a Positive Regulator of Interleukin-34 Production in the Gut . Cells.

Federica Laudisi, Eleonora Franzè, Rachele Frascatani, Lorenzo Tomassini, Elena De Cristofaro, Carmine Stolfi, Giovanni Monteleone (2024). Bromodomain-Containing 4 Is a Positive Regulator of Interleukin-34 Production in the Gut . Cells.

Federica Laudisi, Carmine Stolfi, Ivan Monteleone, Giovanni Monteleone (2023). TGF‐β1 signaling and Smad7 control T‐cell responses in health and immune‐mediated disorders . European Journal of Immunology.

Federica Laudisi, Carmine Stolfi, Teresa Pacifico, Giovanni Monteleone (2023). Impact of Western Diet and Ultra-Processed Food on the Intestinal Mucus Barrier . Biomedicines.

Federica Laudisi, Carmine Stolfi, Teresa Pacifico, Giovanni Monteleone (2023). Impact of Western Diet and Ultra-Processed Food on the Intestinal Mucus Barrier . Biomedicines.

Federica Laudisi, Carmine Stolfi (2023). Advances in Immunotherapy and Innovative Therapeutic Approaches for Cancer Treatment: Editorial to the Special Issue “State-of-the-Art Molecular Oncology in Italy” . International Journal of Molecular Sciences.

Federica Laudisi, Carmine Stolfi (2023). Advances in Immunotherapy and Innovative Therapeutic Approaches for Cancer Treatment: Editorial to the Special Issue “State-of-the-Art Molecular Oncology in Italy” . International Journal of Molecular Sciences.

Federica Laudisi, Carmine Stolfi, Teresa Pacifico, Anderson Luiz-Ferreira, Giovanni Monteleone (2023). Anthelmintic Drugs as Emerging Immune Modulators in Cancer . International Journal of Molecular Sciences.

Federica Laudisi, Carmine Stolfi, Teresa Pacifico, Anderson Luiz-Ferreira, Giovanni Monteleone (2023). Anthelmintic Drugs as Emerging Immune Modulators in Cancer . International Journal of Molecular Sciences.

Federica Laudisi, Silvia Salvatori, Irene Marafini, Giovanni Monteleone, Carmine Stolfi (2023). Helicobacter pylori and Gastric Cancer: Pathogenetic Mechanisms . International Journal of Molecular Sciences.

Federica Laudisi, Silvia Salvatori, Irene Marafini, Giovanni Monteleone, Carmine Stolfi (2023). <i>Helicobacter pylori</i> and Gastric Cancer: Pathogenetic Mechanisms . International Journal of Molecular Sciences.

Federica Laudisi, Eleonora Timperi, Manolo Sambucci, Mattia Laffranchi, Irene Mattiola (2023). SIICA junior faculty: Current activities and future goals . European Journal of Immunology.

Hepcidin Upregulation in Colorectal Cancer Associates with Accumulation of Regulatory Macrophages and Epithelial–Mesenchymal Transition and Correlates with Progression of the Disease <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Cancers.

Smad7 Sustains Stat3 Expression and Signaling in Colon Cancer Cells <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . Cancers.

Federica Laudisi, Claudia Maresca, Giulia Di Maggio, Carmine Stolfi, Marco Colella, Teresa Pacifico, Antonio Di Grazia, Davide Di Fusco, Daniele Congiu, Andrea Martina Guida, et al. (2022). Smad7 Sustains Stat3 Expression and Signaling in Colon Cancer Cells . Cancers.

Federica Laudisi, Carmine Stolfi, Claudia Maresca, Giovanni Monteleone (2022). Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases . Biomedicines.

Federica Laudisi, Adelaide Teofani, Irene Marafini, Daniele Pietrucci, Silvia Salvatori, Valeria Unida, Silvia Biocca, Giovanni Monteleone, Alessandro Desideri (2022). Intestinal Taxa Abundance and Diversity in Inflammatory Bowel Disease Patients: An Analysis including Covariates and Confounders . Nutrients.

Federica Laudisi, Adelaide Teofani, Irene Marafini, Daniele Pietrucci, Silvia Salvatori, Valeria Unida, Silvia Biocca, Giovanni Monteleone, Alessandro Desideri (2022). Intestinal Taxa Abundance and Diversity in Inflammatory Bowel Disease Patients: An Analysis including Covariates and Confounders . Nutrients.

Federica Laudisi, Carmine Stolfi, Claudia Maresca, Giovanni Monteleone (2022). Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases . Biomedicines.

Federica Laudisi and Carmine Stolfi and Gerolamo Bevivino and Claudia Maresca and Eleonora Franz{\`{e}} and Edoardo Troncone and Elisabetta Lolli and Irene Marafini and Daniele Pietrucci and Adelaide Teofani and Antonio Di Grazia and Davide Di Fusco and Alfredo Colantoni and Angela Ortenzi and Alessandro Desideri and Ivan Monteleone and Giovanni Monteleone(2021). GATA6 Deficiency Leads to Epithelial Barrier Dysfunction and Enhances Susceptibility to Gut Inflammation . Journal of Crohn's and Colitis. Oxford University Press ({OUP})

Rami Bechara and Carmela Cela and Anne Hahn and Gizem Kilic and Federica Laudisi and Ellen McAllister and Noushin Mossadegh-Keller(2021). One year of Young EFIS: achievements and future directions . European Journal of Immunology. 51. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1875--1878. Wiley

Vincenzo Dinallo and Davide Di Fusco and Antonio Di Grazia and Federica Laudisi and Edoardo Troncone and Giulia Di Maggio and Eleonora Franz{\`{e}} and Irene Marafini and Alfredo Colantoni and Angela Ortenzi and Carmine Stolfi and Nicola Di Daniele and Ivan Monteleone and Giovanni Monteleone(2021). The Deubiquitinating Enzyme OTUD5 Sustains Inflammatory Cytokine Response in Inflammatory Bowel Disease . Journal of Crohn's and Colitis. Oxford University Press ({OUP})

Federica Laudisi, Antonio Di Grazia, Irene Marafini, Giorgia Pedini, Davide Di Fusco, Vincenzo Dinallo, Eleonora Rosina, Carmine Stolfi, Eleonora Franz&#232;, Pierpaolo Sileri, et al. (2021). The Fragile X Mental Retardation Protein Regulates RIPK1 and Colorectal Cancer Resistance to Necroptosis . Cellular and Molecular Gastroenterology and Hepatology.

(2020). Re to Wi-Fi is an important threat to human health, Environ. Research 164: 405, 2018 . Environmental Research.

Federica Laudisi, Eleonora Franz&#232;, Antonio Di Grazia, Giuseppe Sigismondo Sica, Livia Biancone, Giovanni Monteleone(2020). Interleukin-34 Enhances the Tumor Promoting Function of Colorectal Cancer-Associated Fibroblasts . Cancers. 12. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3537. {MDPI} {AG}

(2020). Macrophages produce and functionally respond to interleukin-34 in colon cancer . Cell death discovery.

Federica Laudisi, Eleonora Franz&#232;, Antonio Di Grazia, Giuseppe Sigismondo Sica, Livia Biancone, Giovanni Monteleone (2020). Interleukin-34 Enhances the Tumor Promoting Function of Colorectal Cancer-Associated Fibroblasts . Cancers.

Federica Laudisi, Giovanni Monteleone, Eleonora Franz&#232;(2020). Expression of Receptors for SARS-CoV-2 in the Gut of Patients with Inflammatory Bowel Disease . Gut and Liver. 14. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 530--531. The Editorial Office of Gut and Liver

Federica Laudisi, Martin Mar&#244;nek, Antonio Di Grazia, Giovanni Monteleone, Carmine Stolfi(2020). Repositioning of Anthelmintic Drugs for the Treatment of Cancers of the Digestive System . International Journal of Molecular Sciences. 21. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4957. {MDPI} {AG}

Federica Laudisi, Martin Mar&#244;nek, Antonio Di Grazia, Giovanni Monteleone, Carmine Stolfi (2020). Repositioning of Anthelmintic Drugs for the Treatment of Cancers of the Digestive System . International Journal of Molecular Sciences.

(2020). Rafoxanide Induces Immunogenic Death of Colorectal Cancer Cells . Cancers.

(2020). Interleukin-34 Stimulates Gut Fibroblasts to Produce Collagen Synthesis . Journal of Crohn's and Colitis.

(2020). Albendazole negatively regulates keratinocyte proliferation . Clinical Science.

(2020). Young immunologists of Europe, unite! . European Journal of Immunology.

Federica Laudisi, Patrizio Scarozza, Irene Marafini, Edoardo Troncone, Heike Schmitt, Marco Vincenzo Lenti, Stefania Costa, Irene Rocchetti, Elena De Cristofaro, Silvia Salvatori, et al. (2020). Extent of Mucosal Inflammation in Ulcerative Colitis Influences the Clinical Remission Induced by Vedolizumab . Journal of Clinical Medicine.

Federica Laudisi, Patrizio Scarozza, Irene Marafini, Edoardo Troncone, Heike Schmitt, Marco Vincenzo Lenti, Stefania Costa, Irene Rocchetti, Elena De Cristofaro, Silvia Salvatori, et al. (2020). Extent of Mucosal Inflammation in Ulcerative Colitis Influences the Clinical Remission Induced by Vedolizumab . Journal of Clinical Medicine.

(2019). Impact of Food Additives on Gut Homeostasis . Nutrients.

Federica Laudisi, Carmine Stolfi, Giovanni Monteleone (2019). Impact of Food Additives on Gut Homeostasis . Nutrients.

Federica Laudisi, Antonio Di Grazia, Veronica De Simone, Fabio Cherubini, Alfredo Colantoni, Angela Ortenzi, Eleonora Franz&#232;, Vincenzo Dinallo, Davide Di Fusco, Ivan Monteleone, et al. (2019). Induction of endoplasmic reticulum stress and inhibition of colon carcinogenesis by the anti-helmintic drug rafoxanide . Cancer Letters.

(2019). Cadherin-11 is a Regulator of Intestinal Fibrosis . Journal of Crohn's and Colitis.

(2019). Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells . Molecular Oncology.

(2019). Neutrophil extracellular traps sustain inflammatory signals in ulcerative colitis . J Crohn’s Colitis.

(2019). Protective effects of Aryl hydrocarbon Receptor signalling in celiac disease mucosa and in poly I:C-induced small intestinal atrophy mouse model .

(2018). The food additive maltodextrin promotes endoplasmic reticulum stress-driven mucus depletion and exacerbates intestinal inflammation . Cellular and Molecular Gastroenterology and Hepatology.

Federica Laudisi, Fabio Cherubini, Giovanni Monteleone, Carmine Stolfi (2018). STAT3 Interactors as Potential Therapeutic Targets for Cancer Treatment . International Journal of Molecular Sciences.

(2018). STAT3 Interactors as Potential Therapeutic Targets for Cancer Treatment . International Journal of Molecular Sciences.

(2018). Metformin inhibits inflammatory signals in the gut by controlling AMPK and p38 MAP kinase activation . Clinical Science.

(2017). NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release . Frontiers in Immunology.

(2017). Smad7 positively regulates keratinocyte proliferation in psoriasis . Br J Dermatol.

(2017). CCL20 Is Negatively Regulated by TGF-β1 in Intestinal Epithelial Cells and Reduced in Crohn's Disease Patients With a Successful Response to Mongersen, a Smad7 Antisense Oligonucleotide . J Crohns Colitis.

(2017). Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death . Cell Death Dis.

Khameneh, H.J., Ho, A.W.S., Laudisi, F., Derks, H., Kandasamy, M., Sivasankar, B., Teng, G.G., Mortellaro, A.(2017). C5a regulates IL-1β production and leukocyte recruitment in a murine model of monosodium urate crystal-induced peritonitis . Frontiers in Pharmacology. 8. (JAN).

Monteleone, I., Marafini, I., Dinallo, V., Di Fusco, D., Troncone, E., Zorzi, F., Laudisi, F., Monteleone, G.(2017). Sodium chloride-enriched Diet Enhanced Inflammatory Cytokine Production and Exacerbated Experimental Colitis in Mice . Journal of Crohn's &amp; colitis. 11. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 237-245.

Laudisi, F., Dinallo, V., Di Fusco, D., Monteleone, G.(2016). Smad7 and its potential as therapeutic target in inflammatory bowel diseases . Current Drug Metabolism. 17. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 303-306.

Li, L., Ng, D.S.W., Mah, W.-C., Almeida, F.F., Rahmat, S.A., Rao, V.K., Leow, S.C., Laudisi, F., Peh, M.T., Goh, A.M., et al.(2015). A unique role for p53 in the regulation of M2 macrophage polarization . Cell Death and Differentiation. 22. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1081-1093.

Franz&#233;, E., Monteleone, I., Cupi, M.L., Mancia, P., Caprioli, F., Marafini, I., Colantoni, A., Ortenzi, A., Laudisi, F., Sica, G., et al.(2015). Interleukin-34 sustains inflammatory pathways in the gut . Clinical Science. 129. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 271-280.

Laudisi, F., Vigan&#242;, E., Mortellaro, A.(2014). Tyrosine kinases: the molecular switch for inflammasome activation . Cellular and Molecular Immunology. 11. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 129-131.

Laudisi, F., Spreafico, R., Evrard, M., Hughes, T.R., Mandriani, B., Kandasamy, M., Morgan, B.P., Sivasankar, B., Mortellaro, A.(2013). Cutting edge: The NLRP3 inflammasome links complement-mediated inflammation and IL-1β release . Journal of Immunology. 191. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1006-1010.

Sambucci, M., Laudisi, F., Novelli, F., Bennici, E., Rosado, M.M., Pioli, C.(2013). Effects of PARP-1 deficiency on Th1 and Th2 cell differentiation . The Scientific World Journal. 2013.

Licandro, G., Ling Khor, H., Beretta, O., Lai, J., Derks, H., Laudisi, F., Conforti-Andreoni, C., Liang Qian, H., Gee Teng, G., Ricciardi-Castagnoli, P., et al.(2013). The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells . European Journal of Immunology. 43. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2126-2137.

Laudisi, F., Sambucci, M., Nasta, F., Pinto, R., Lodato, R., Altavista, P., Lovisolo, G.A., Marino, C., Pioli, C.(2012). Prenatal exposure to radiofrequencies: Effects of WiFi signals on thymocyte development and peripheral T cell compartment in an animal model . Bioelectromagnetics. 33. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 652-661.

Zambetti, L.P., Laudisi, F., Licandro, G., Ricciardi-Castagnoli, P., Mortellaro, A.(2012). The rhapsody of NLRPs: Master players of inflammation ... and a lot more . Immunologic Research. 53. (1-3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 78-90.

Sambucci, M., Laudisi, F., Nasta, F., Pinto, R., Lodato, R., Lopresto, V., Altavista, P., Marino, C., Pioli, C.(2011). Early life exposure to 2.45GHz WiFi-like signals: Effects on development and maturation of the immune system . Progress in Biophysics and Molecular Biology. 107. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 393-398.

Laudisi, F., Sambucci, M., Pioli, C.(2011). Poly (ADP-Ribose) polymerase-1 (PARP-1) as immune regulator . Endocrine, Metabolic and Immune Disorders - Drug Targets. 11. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 326-333.

Nasta, F., Laudisi, F., Sambucci, M., Rosado, M.M., Pioli, C.(2010). Increased Foxp3+ regulatory T cells in poly(ADP-ribose) polymerase-1 deficiency . Journal of Immunology. 184. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3470-3477.

Sambucci, M., Laudisi, F., Nasta, F., Pinto, R., Lodato, R., Altavista, P., Lovisolo, G.A., Marino, C., Pioli, C.(2010). Prenatal exposure to non-ionizing radiation: Effects of WiFi signals on pregnancy outcome, peripheral B-cell compartment and antibody production . Radiation Research. 174. (6 A). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 732-740.

PREPRINT

Federica Laudisi, Rachele Frascatani, Carmine Stolfi, Giovanni Monteleone (2026). Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer .

WORKING PAPER

Immunologic Drivers and Restraints in Colitis-Associated Colorectal Cancer .