プロフィール詳細

プロジェクトを作成

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Dr. Felipe S.に依頼

Brazil

Freelance Virologist and Bioinformatican | Expert in Virtual Screening and Biologic Assays

プロフィール概要

I have a Ph.D in Biotechnology from Federal University of São João del-Rei (Divinópolis, Brazil), which I obtained screening promising antiviral compounds against Zika virus. I have also completed postdoctoral training at Adolfo Lutz Institute (São Paulo, Brazil) studying the development of vaccines and new imunoassays for Zika virus. In addition, I also study the mutattional profile of SARS-CoV-2 in Brazil. I am skilled at technical writing and scientific presentations. I have authored or co-authored 8 scientific manuscripts and two patents since 2016.

専門分野

• ★ Microbiology
• ★ Bioinformatics
• ★ Drug Design
• ☆ Molecular Modeling
• ☆ Molecular Docking
• ☆ Virology
• ☆ Zika Virus
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biotechnology & Bioengineering
• ☆ Nanobiotechnology
• ☆ Cell Culture
• ☆ Identity
• ☆ Drug Discovery
• ☆ Medicinal Chemistry
• ☆ Drug Development
• ☆ Infectious Disease
• ☆ Tropical Medicine
• ☆ Dengue
• ☆ Inflammation
• ☆ Technical & Scientific Writing

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, Copywriting

Research Feasibility Study, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Processing, Image Analysis, Data Visualization

職務経験

Postdoctoral Fellow

Universidade Federal de Minas Gerais -Brazil

1月 2021 - 現在

Postdoctoral fellow

Adolfo Lutz Institute

7月 2020 - 12月 2020

学歴

Postdoctoral fellow

Adolfo Lutz Institute

7月 2020 - 12月 2020

Ph.D.

Federal University of São João del-Rei

8月 2016 - 12月 2019

認定資格

• Biosafety Level-3 (BSL-3) Lab

  Universidade Federal de Minas Gerais -Brazil

  6月 2022 - 現在

出版物

JOURNAL ARTICLE

Felipe Santos, Julia LeCher, Keivan Zandi, Vivian Vasconcelos Costa, Franck Amblard, Sijia Tao, Dharmeshkumar Patel, Sujin Lee, Matheus Rodrigues Goncalves, Celso Martins Queroz-Junior, et al. (2022). Discovery of a 2′-Fluoro,2′-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice . Microorganisms.

NS2B‐NS3 protease inhibitors as promising compounds in the development of antivirals against Zika virus: A systematic review @article{2021, doi = {10.1002/jmv.27386}, url = {https://doi.org/10.1002%2Fjmv.27386}, year = 2021, month = {oct}, publisher = {Wiley}, author = {Damiana Ant{\^{o}}nia de F{\'{a}}tima Nunes and Felipe Rocha da Silva Santos and Sara Thamires Dias Fonseca and William Gustavo Lima and Waleska Stephanie da Cruz Nizer and Jaqueline Maria Siqueira Ferreira and Jos{\'{e}} Carlos Magalh{\~{a}}es}, title = {{NS}2B-{NS}3 protease inhibitors as promising compounds in the development of antivirals against Zika virus: A systematic review}} . Journal of Medical Virology.

Mutational profile confers increased stability of SARS-CoV-2 spike protein in Brazilian isolates @article{2021, doi = {10.1080/07391102.2021.1982775}, url = {https://doi.org/10.1080%2F07391102.2021.1982775}, year = 2021, month = {oct}, publisher = {Informa {UK} Limited}, pages = {1--6}, author = {Felipe Rocha da Silva Santos and Marcela Santiago Pacheco de Azevedo and Monica Bielavsky and Hernan Hermes Monteiro da Costa and Daniela Gomes Ribeiro and Gleidson Guedes do Nascimento and Gabrielle Menezes Paz Marcondes and Beatriz Portugal de Castro and Daniel Ferreira de Lima Neto and Carlos Roberto Prudencio}, title = {Mutational profile confers increased stability of {SARS}-{CoV}-2 spike protein in Brazilian isolates}} . Journal of Biomolecular Structure and Dynamics.

(2020). Identification of a Potential Zika Virus Inhibitor Targeting NS5 Methyltransferase Using Virtual Screening and Molecular Dynamics Simulations . Journal of Chemical Information and Modeling.

Santos, F.R.S., Nunes, D.A.F., Lima, W.G., Davyt, D., Santos, L.L., Taranto, A.G., M. S. Ferreira, J.(2020). Identification of Zika Virus NS2B-NS3 Protease Inhibitors by Structure-Based Virtual Screening and Drug Repurposing Approaches . Journal of Chemical Information and Modeling.

(2019). Bauhinia holophylla (Bong.) Steud. leaves-derived extracts as potent anti-dengue serotype 2 . Natural Product Research.

(2019). Synthesis and Evaluation of the in vitro Antimicrobial Activity of Triazoles, Morpholines and Thiosemicarbazones . Medicinal Chemistry.

Andrade, J.T., Santos, F.R.S., Lima, W.G., Sousa, C.D.F., Oliveira, L.S.F.M., Ribeiro, R.I.M.A., Gomes, A.J.P.S., Araújo, M.G.F., Villar, J.A.F.P., Ferreira, J.M.S.(2018). Design, synthesis, biological activity and structure-activity relationship studies of chalcone derivatives as potential anti-Candida agents . Journal of Antibiotics. 71. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 702-712.

(2018). Triazole-chalcones: Lack of antibacterial, anti-candida, and anti-dengue virus activities . Journal of Pharmaceutical Negative Results.

Alves, S.L.G., Paixão, N., Ferreira, L.G.R., Santos, F.R.S., Neves, L.D.R., Oliveira, G.C., Cortes, V.F., Salomé, K.S., Barison, A., Santos, F.V., et al.(2015). γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect . Bioorganic and Medicinal Chemistry. 23. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4397-4404.