プロフィール詳細

プロジェクトを作成

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Dr. Ferdi Ridvan K.に依頼

United States

Scientific Consultant & Writer | Expert in Brain Organoids, Stem Cell Disease Models & Neural Circuits

プロフィール概要

I am a PhD-level neuroscientist and stem cell biologist specializing in the development of advanced human brain organoids and multi-organoid assembloids. My work combines stem cell biology, developmental neuroscience, and functional imaging to build physiologically relevant in-vitro models of the human brain for disease modeling and therapeutic discovery. I have extensive experience generating region-specific organoids - including retinal, cortical, thalamic, and neuroendocrine models - as well as complex assembloids designed to reconstruct functional neural circuits. My current research focuses on modeling human sleep and circadian biology using thalamocortical and neuroendocrine organoid systems. My technical expertise spans organoid engineering, electrophysiology, and advanced imaging, including Microelectrode Array (MEA) recordings, confocal and two-photon microscopy, calcium and voltage imaging, and single-cell RNA sequencing with downstream data analysis. In addition to experimental work, I provide scientific consulting, protocol development, experimental design, and high-level scientific writing support. I regularly assist academic groups, biotech startups, and pharmaceutical teams in establishing organoid platforms, designing in-vitro disease models, analyzing complex datasets, and preparing competitive grant proposals.

専門分野

• ★ Stem Cell Research
• ★ Developmental Neuroscience
• ★ 3D Cell Culture
• ☆ Developmental Biology
• ☆ Embryology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cytogenetics
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Neuroscience
• ☆ Neurochemistry
• ☆ Neurophysiology
• ☆ Visual Neuroscience
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Data Analysis
• ☆ Image Processing
• ☆ Data Visualization
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Biomarker Discovery
• ☆ Cell Banking
• ☆ Large Scale Cell Culture
• ☆ Biomolecular Engineering
• ☆ Genetic Engineering
• ☆ Gene Editing/CRISPR
• ☆ Gene Delivery
• ☆ Circadian Rhythm Research
• ☆ Cell Aging

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting, Creative Writing, Newswriting, General Proofreading & Editing

Research Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Image Analysis, Data Visualization

Product Development Concept Development

職務経験

Postdoctoral Associate

Yale University School of Medicine

11月 2020 - 現在

学歴

Ph.D. (Neurobiology )

Freie Universität Berlin

10月 2015 - 10月 2020

MSc (Molecular Biology and Genetics)

Bogazici Üniversitesi - Kuzey Kampüsü

3月 2013 - 8月 2015

Bachelor (Molecular Biology and Genetics)

Middle East Technical University

9月 2007 - 6月 2012

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Ferdi Ridvan Kiral, Woo Sub Yang, Onur Iyilikci, Xiaona Lu, Jonghun Kim, Mu Seog Choe, Cynthia Lo, Mei Zhong, Kun-Yong Kim, Yong-Hui Jiang, et al. (2026). Generation of human pineal gland organoids with melatonin production for disease modeling . Cell Stem Cell.

Ferdi Ridvan Kiral, Woo Sub Yang, In-Hyun Park (2024). Telencephalic organoids as model systems to study cortical development and diseases . Organoid.

Ferdi Ridvan Kiral, Museog Choe, In-Hyun Park (2023). Diencephalic organoids – A key to unraveling development, connectivity, and pathology of the human diencephalon . Frontiers in Cellular Neuroscience.

Ferdi Ridvan Kiral, Bilal Cakir, Yoshiaki Tanaka, Jonghun Kim, Woo Sub Yang, Fabien Wehbe, Young-Jin Kang, Mei Zhong, Gizem Sancer, Sang-Hun Lee, et al. (2023). Generation of ventralized human thalamic organoids with thalamic reticular nucleus . Cell Stem Cell.

Ferdi Ridvan Kiral(2022). Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development . Frontiers in Cell and Developmental Biology. 10. Frontiers Media {SA}

Ferdi Ridvan Kiral(2022). Human Down syndrome microglia are up for a synaptic feast . Cell Stem Cell. 29. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1007--1008. Elsevier {BV}

Ferdi Ridvan Kiral(2022). Region Specific Brain Organoids to Study Neurodevelopmental Disorders . International Journal of Stem Cells. 15. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 26--40. Korean Society for Stem Cell Research

Ferdi Ridvan Kiral(2022). Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids . Nature Communications. 13. (1). Springer Science and Business Media {LLC}

Ferdi Ridvan Kiral(2021). Brain connectivity inversely scales with developmental temperature in Drosophila . Cell Reports. 37. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 110145. Elsevier {BV}

Ece Terzioğlu Kara, Ferdi Rıdvan Kiral, Arzu Öztürk Çolak, Arzu Çelik (2020). Generation and characterization of inner photoreceptor‐specific enhancer‐trap lines using a novel piggyBac‐Gal4 element in Drosophila . Archives of Insect Biochemistry and Physiology.

(2020). Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring . Nature Communications.

(2019). Serial Synapse Formation through Filopodial Competition for Synaptic Seeding Factors . Developmental Cell.

Jin, E.J., Kiral, F.R., Ozel, M.N., Burchardt, L.S., Osterland, M., Epstein, D., Wolfenberg, H., Prohaska, S., Hiesinger, P.R.(2018). Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals . Current Biology. 28. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1027-1038.e4.

Kiral, F.R., Kohrs, F.E., Jin, E.J., Hiesinger, P.R.(2018). Rab GTPases and Membrane Trafficking in Neurodegeneration . Current Biology. 28. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString R471-R486.

Jin, E.J., Kiral, F.R., Hiesinger, P.R.(2018). The where, what, and when of membrane protein degradation in neurons . Developmental Neurobiology. 78. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 283-297.

OTHER

F. Ridvan Kiral, Suchetana B. Dutta, Gerit Arne Linneweber, Caroline Poppa, Max von Kleist, Bassem A. Hassan, Peter Robin Hiesinger(2021). Variable brain wiring through scalable and relative synapse formation in Drosophila . Cold Spring Harbor Laboratory

PREPRINT

(2020). Systematic functional analysis of Rab GTPases reveals limits of neuronal robustness in Drosophila . BioRxiv.