プロフィール詳細

プロジェクトを作成

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Dr. FNU N.に依頼

Pakistan

Academic writer and Computational Structural Biologist with wet lab experience from 6+ years

プロフィール概要

Having both wet lab and dry lab experience. In Dry lab I have expertise in Molecular Docking, Molecular Dynamics Simulation and Virtual Screening. I have specialization in Molecular Docking of proteins having Post-translational Modifications such as phosphorylation and acetylation. In wet lab I have expertise in DNA/RNA/Protein Extraction, PCR, Gel Electrophoresis, SDS PAGE, Western Blot, Two-dimensional gel electrophoresis.

専門分野

• ☆ Molecular Modeling
• ☆ Molecular Docking
• ☆ Chemoinformatics
• ☆ Computational Biology
• ☆ Biochemistry
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ PCR
• ☆ Kinases
• ☆ Biophysics
• ☆ Bioinformatics
• ☆ Structural Bioinformatics
• ☆ Blotting
• ☆ Circadian Rhythm Research

サービス

• Writing
• Research
• Consulting

Writing Technical Writing

Research Scientific and Technical Research

Consulting Healthcare Consulting

職務経験

PhD Research Student

Functional Informatics Lab, National Center for Bioinformatics, Quaid-i-Azam University, Islamabad

2月 2016 - 6月 2022

Guest Researcher

National Institute on Aging, National Institute of Health, USA

2月 2020 - 7月 2020

学歴

PhD (Bioinformatics)

Quaid-i-Azam University, Islamabad

2月 2016 - 6月 2022

認定資格

• n/a

  n/a

  1月 2023 - 1月 2023

出版物

JOURNAL ARTICLE

Najumuddin, Muhammad Fakhar, Sana Zahid, Sajid Rashid(2022). Structural basis of Klotho binding to VEGFR2 and TRPC1 and repurposing calcium channel blockers as TRPC1 antagonists for the treatment of age-related cardiac hypertrophy . Archives of Biochemistry and Biophysics. 719. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 109171. Elsevier {BV}

Najumuddin, Muhammad Fakhar, Sajid Rashid(2020). Evidence for NAD+-dependent histone dynamics and tunneling associated conformational transitions in circadian deacetylase SIRT1 . Journal of Molecular Graphics and Modelling. 99. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 107646. Elsevier {BV}

Najumuddin, Mehreen Gul, Muhammad Fakhar, Sajid Rashid(2019). Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors . PLOS ONE. 14. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e0225132. Public Library of Science ({PLoS})

Najumuddin, Muhammad Fakhar, Mehreen Gul, Sajid Rashid(2018). Antagonistic role of Klotho-derived peptides dynamics in the pancreatic cancer treatment through obstructing WNT-1 and Frizzled binding . Biophysical Chemistry. 240. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 107--117. Elsevier {BV}

Najumuddin, Muhammad Fakhar, Mehreen Gul, Sajid Rashid(2018). Interactive structural analysis of βTrCP1 and PER2 phosphoswitch binding through dynamics simulation assay . Archives of Biochemistry and Biophysics. 651. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 34--42. Elsevier {BV}