プロフィール詳細

プロジェクトを作成

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Dr. Forrest W.に依頼

United States

PhD Bioinformatician | Multi-Omics & Spatial Transcriptomics Expert | NGS Pipeline Development

プロフィール概要

I am a PhD scientist with over 9 years of combined academic and industry experience specializing in multi-omics data analysis, bioinformatics pipeline development, and spatial transcriptomics. My expertise bridges experimental biology and computational analysis, enabling me to translate complex genomic data into actionable biological insights. At AbbVie, I established and optimized next-generation sequencing workflows, built production-grade bioinformatics pipelines using Nextflow and Snakemake on HPC infrastructure, and onboarded two spatial biology platforms (NanoString CosMx and Curio Trekker). I have extensive experience analyzing bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics data, with a focus on rigorous quality control, statistical analysis, and biological interpretation. My technical skills include proficiency in Python and R for data analysis, experience with pipeline orchestration tools, containerization (Docker, Singularity), and cloud computing (AWS, Hetzner). I have worked with diverse sample types including human donor tissue, animal models, and iPSC systems, and have collaborated with external CROs and academic partners on large-scale studies. During my PhD at UC Irvine, I developed custom bioinformatics approaches combining transcriptomics, proteomics, and phylogenetics to study neurodevelopment. I have authored multiple peer-reviewed publications and have experience communicating complex technical results to both specialist and non-specialist audiences. I currently volunteer as a bioinformatician for the Open Insulin Foundation, applying computational biology to support community health initiatives. I can help with RNA-seq analysis (bulk and single-cell), spatial transcriptomics data processing, pipeline development, multi-omics integration, variant calling, proteomics analysis, and custom bioinformatics solutions tailored to your research needs.

専門分野

• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Omics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Proteomics
• ☆ Genomics
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ RNA Sequencing
• ☆ Neuroscience
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Systems Biology
• ☆ Phylogenetics
• ☆ Python
• ☆ R

サービス

• Writing
• Research
• Consulting

Writing Technical Writing, General Proofreading & Editing

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

職務経験

Senior Scientist I

AbbVie

3月 2024 - 11月 2025

Postdoctoral Fellow

AbbVie

7月 2023 - 3月 2024

Postdoctoral Fellow

University of California, Irvine

11月 2022 - 7月 2023

学歴

PhD in Neurobiology and Behavior

University of California, Irvine

7月 2016 - 10月 2022

BS in Neuroscience and Behavior

University of Notre Dame

8月 2012 - 5月 2016

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Forrest Weghorst, Martí Torres Marcén, Garrison Faridi, Yuh Chwen G. Lee, Karina S. Cramer (2024). Deep Conservation and Unexpected Evolutionary History of Neighboring lncRNAs MALAT1 and NEAT1 . Journal of Molecular Evolution.

Forrest Weghorst, Yeva Mirzakhanyan, Kiersten L. Hernandez, Paul D. Gershon, Karina S. Cramer (2022). Non-Apoptotic Caspase Activity Preferentially Targets a Novel Consensus Sequence Associated With Cytoskeletal Proteins in the Developing Auditory Brainstem . Frontiers in Cell and Developmental Biology.

Forrest Weghorst, Yeva Mirzakhanyan, Kian Samimi, Mehron Dhillon, Melanie Barzik, Lisa L. Cunningham, Paul D. Gershon, Karina S. Cramer (2020). Caspase-3 Cleaves Extracellular Vesicle Proteins During Auditory Brainstem Development . Frontiers in Cellular Neuroscience.

Forrest P Weghorst, Karina S Cramer(2019). The evolution of hearing and balance . eLife. 8. {eLife} Sciences Publications, Ltd

Kirk L. Mecklenburg, Forrest P. Weghorst, Stephanie A. Freed, Joseph E. O’Tousa (2018). Discordant Responses to MAPK Pathway Stimulation Include Axonal Growths in Adult Drosophila Photoreceptors . Frontiers in Molecular Neuroscience.