プロフィール詳細

プロジェクトを作成

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Dr. Giuseppe C.に依頼

United Kingdom

Postdoctoral Researcher in Stem Cell Biology and Organoid Technology

プロフィール概要

I am a postdoctoral researcher in stem cell and organoid biology with 5+ years of experience across academia and translational research. I completed a PhD and worked as a postdoc at University College London (UCL), focusing on the development of organoid models from human tissues and amniotic fluid. I applied this technology to model prenatal development and congenital diseases. My work integrates cutting-edge organoid technology, single-cell gene expression profiling, and biomaterials engineering. I have extensive expertise in: - Derivation, expansion, and characterization of organoids from fetal and adult human/mouse tissues - Protocol development for a broad range of tissue-derived organoids (lung, kidney, intestinal, gastric, esophagus, placenta organoids) - application of confocal microscopy and tissue clearing - functional differentiation assays - co-culture models of mesenchyme and endothelial cells and complex Assembloid models - Disease modelling (congenital/genetic disease, cancer) - Hydrogel-based tissue engineering (decellularization of organs, hydrogel development, ECM) - Single-cell RNA-seq library prep and data interpretation - grant proposal and research paper writing, editing and evaluation I offer consultancy in organoid model design, protocol troubleshooting, data analysis, manuscript/grant writing, and project evaluation. I am co-inventor on an international patent on fetal fluid-derived organoids and author of multiple papers in high impact factor journals. I regularly lecture on organoid biology at UCL and have supervised and advised several MSc and MD students in the lab. Fluent in English and Italian. Open to short- and medium-term freelance consulting projects, especially with biotech, startups, and research institutions.

専門分野

• ☆ Developmental Biology
• ☆ Embryology
• ☆ Molecular Biology
• ☆ RNA Sequencing
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Stem Cell Research
• ☆ Biotechnology & Bioengineering
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Fluorescence Microscopy
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Large Scale Cell Culture
• ☆ 3D Cell Culture
• ☆ Tissue Engineering
• ☆ Cytometry

サービス

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing, General Proofreading & Editing, Translation

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

Product Development Recipe Development, Product Evaluation

職務経験

Postdoctoral Researcher

University College London

7月 2024 - 現在

PhD student

University College London

7月 2021 - 6月 2024

Research assistant

UCL Great Ormond Street Institute of Child Health

1月 2021 - 7月 2021

Erasmus Traineeship Fellow

UCL Great Ormond Street Institute of Child Health

3月 2020 - 3月 2021

MSc trainee

University of Pavia

6月 2019 - 3月 2020

学歴

PhD Stem Cells and Regenerative Medicine (Division of Surgery and Interventional Science, Faculty of Medical Sciences)

University College London

2021 - 2024

Master’s Degree - Medical and Pharmaceutical Biotechnology

University of Pavia

2017 - 2019

Bachelor’s Degree - Biotechnology

Università degli Studi della Tuscia

2013 - 2017

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Mattia Francesco Maria Gerli, Giuseppe Calà, Max Arran Beesley, Beatrice Sina, Lucinda Tullie, Kylin Yunyan Sun, Francesco Panariello, Federica Michielin, Joseph R. Davidson, Francesca Maria Russo, et al. (2025). Author Correction: Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids . Nature Medicine.

Mattia Francesco Maria Gerli, Giuseppe Calà, Max Arran Beesley, Beatrice Sina, Lucinda Tullie, Kylin Yunyan Sun, Francesco Panariello, Federica Michielin, Joseph R. Davidson, Francesca Maria Russo, et al. (2024). Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids . Nature Medicine.

Gerli, M.F.M., Calà, G., Beesley, M.A., Sina, B., Tullie, L., Sun, K.Y., Panariello, F., Michielin, F., Davidson, J.R., Russo, F.M., et al.(2024). Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids . Nature Medicine. 30. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 875-887.

Giuseppe Calà, Beatrice Sina, Paolo De Coppi, Giovanni Giuseppe Giobbe, Mattia Francesco Maria Gerli(2023). Primary human organoids models: Current progress and key milestones . Frontiers in Bioengineering and Biotechnology. 11. Frontiers Media {SA}

Calà, G., Sina, B., De Coppi, P., Giobbe, G.G., Gerli, M.F.M.(2023). Primary human organoids models: Current progress and key milestones . Frontiers in Bioengineering and Biotechnology. 11.

(2021). Paediatric gastric organoids as a tool for disease modelling and clinical translation . Pediatric surgery international.

Jones, B.C., Calà, G., De Coppi, P., Giobbe, G.G.(2021). Paediatric gastric organoids as a tool for disease modelling and clinical translation . Pediatric Surgery International. 37. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 317-324.

PREPRINT

Brendan C Jones, Giada Benedetti, Giuseppe Calà, Lucinda Tullie, Ian C Simcock, Roberto Lutman, Monika Balys, Ramin Amiri, Jahangir Sufi, Owen Arthurs, et al. (2024). Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia .

Mattia Francesco Maria Gerli, Giuseppe Calà, Max Arran Beesley, Beatrice Sina, Lucinda Tullie, Francesco Panariello, Federica Michielin, Kylin Sun Yunyan, Joseph R Davidson, Francesca Maria Russo, et al. (2023). Single cell-guided prenatal derivation of primary epithelial organoids from the human amniotic and tracheal fluids .

OTHER

Jones, B.C., Benedetti, G., Calà, G., Tullie, L., Simcock, I.C., Lutman, R., Balys, M., Amiri, R., Sufi, J., Arthurs, O., et al.(2024). Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia . bioRxiv.

Gerli, M.F.M., Calà, G., Beesley, M.A., Sina, B., Tullie, L., Panariello, F., Michielin, F., Yunyan, K.S., Davidson, J.R., Russo, F.M., et al.(2023). Single cell-guided prenatal derivation of primary epithelial organoids from the human amniotic and tracheal fluids . bioRxiv.