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プロフィール詳細
Dr. Ganapathy S.に依頼
United States
Freelance Biochemist & Cancer Biologist, 15+ years experience in cancer research
プロフィール概要
専門分野
サービス
Research
Fact Checking,
Scientific and Technical Research
Consulting
Scientific and Technical Consulting
職務経験
Visiting Assistant Professor
Wheaton College, Norton MA
9月 2024 - 現在
Senior Scientist
EMD Serono
8月 2021 - 3月 2024
Scientist
Montai Health Inc (Flagship Pioneering)
10月 2020 - 7月 2021
Postdoctoral Fellow
Massachusetts Institute of Technology
3月 2015 - 9月 2020
学歴
PhD, Biochemistry
Rutgers University, Newark - United States
8月 2008 - 5月 2014
認定資格
- 認定資格の詳細は未入力です。
出版物
JOURNAL ARTICLE
Ganapathy Sriram, Tiffany R. Emmons, Lauren E. Milling, Darrell J. Irvine, Michael B Yaffe (2022). Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade . Molecular & Cellular Oncology.
Ganapathy Sriram, Lauren E. Milling, Jung-Kuei Chen, Yi Wen Kong, Brian A. Joughin, Wuhbet Abraham, Susanne Swartwout, Erika D. Handly, Darrell J. Irvine, Michael B. Yaffe(2021). The injury response to DNA damage in live tumor cells promotes antitumor immunity . Science Signaling. 14. (705). American Association for the Advancement of Science ({AAAS})
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints <head>
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(2019). Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer . Cancer research.
(2019). Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner . The journal of trauma and acute care surgery.
(2018). MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis . Proceedings of the National Academy of Sciences of the United States of America.
(2017). Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression . Molecular Cancer Research.
(2015). Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway . Nature Chemical Biology.
(2015). Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk. Oncogene.
(2014). Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity. Frontiers in Immunology.
(2014). Crk at the quarter century mark: perspectives in signaling and cancer. Journal of Cellular Biochemistry.
(2012). Commentary: The carboxyl-terminal Crk SH3 domain: Regulatory strategies and new perspectives. FEBS letters.
(2012). Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nature Chemical Biology.
(2011). Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation. Oncogene.
(2011). Expression of type II chorionic gonadotropin genes supports a role in the male reproductive system. Molecular and Cellular Biology.
(2010). Emerging roles for crk in human cancer. Genes and Cancer.
CONFERENCE POSTER
(2014). Tyrosine Phosphorylation Controls Non-canonical Domain Utilization in the Signaling Adaptor Protein Crk. FASEB – Protein Phosphorylation, Cellular Plasticity and Signal Rewiring.
(2011). Non-canonical Signaling Pathway for Crk Mediated by Tyrosine Phosphorylation of the C-terminal SH3 domain. Protein Modules and Networks in Health and Disease.
(2011). Phosphorylation of Crk at Tyrosine 251 in the RT loop of the SH3C domain downstream of EGFR: Novel Role in Abl Transactivation. Experimental Biology.
(2010). Phosphorylation of the Crk Adaptor Protein at Y251: Novel Role in Abl Kinase Trans-activation. Meeting on Protein Phosphorylation and Cell Signaling.
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