プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Guanming J.に依頼

United States

Cancer Biologist | Epigenetics Benchwork & Multi-Omics (ChIP/ATAC-seq/RNA-seq/CRISPR) Analyst

プロフィール概要

As a Cancer Biologist with a strong background in both wet-lab execution and bioinformatics, I bridge the gap between bench experiment design and complex data analysis. Unlike pure computational biologists, I have extensive hands-on experience in the laboratory, allowing me to fully understand the biological nuances behind the datasets I analyze. My research heavily focuses on oncology, metabolic regulation, and epigenetic mechanisms, particularly involving chromatin remodeling (e.g., PBRM1/VHL mutations), hypoxia-inducible factors (HIF), and tumor microenvironments in models like clear cell renal cell carcinoma (ccRCC) and AML. Core Expertise & Services: Epigenetics & Wet-Lab Benchwork: Extensive experience in molecular cloning, mammalian cell culture, and functional target validation. I specialize in the end-to-end execution of epigenomic assays—such as chromatin profiling and handling complex biological samples—to investigate gene regulation and chromatin dynamics. Epigenomic Data Integration (Bioinformatics): Capable of independently processing high-throughput sequencing data generated from bench work. I possess deep expertise in analyzing epigenomic and transcriptomic datasets, including ChIP-seq, ATAC-seq, CUT&RUN, and RNA-seq. I write custom R scripts (DESeq2, ggplot2, ComplexHeatmap) for differential expression, peak calling interpretation, and complex multi-omic visualization. Scientific Consulting & Pipeline Strategy: Because I understand both the "wet" and "dry" sides of science, I can assist biotech teams and academic labs in designing robust epigenetic experiments, troubleshooting NGS library preparations, and interpreting chromatin accessibility or binding results with true biological relevance. Whether you need a consultant to design an epigenome profiling strategy, validate molecular targets, or translate raw sequencing data into publication-ready figures, I provide solutions grounded in actual bench experience.

専門分野

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Epigenetics
• ☆ R

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Medical Writing, Technical Writing, General Proofreading & Editing

Research Fact Checking, Gap Analysis, Scientific and Technical Research

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Data Mining, Data Cleaning, Data Processing

Product Development Quality Assurance & Control (QA/QC)

職務経験

Research Fellow

Harvard Medical School/Dana-Farber Cancer Institute

6月 2026 - 現在

Purdue University System

6月 2020 - 現在

学歴

PhD

Purdue University

8月 2019 - 6月 2026

認定資格

• Bioinformatician

  cold spring harbour laboratory

  1月 2024 - 現在

出版物

PREPRINT

Guanming Jiao, Alisha Dhiman, Mitchell G. Ayers, Jamie L. McCuiston, Aparna B. Shinde, Saeed Salehin Akhand, Juan Jauregui-Lozano, Marco Hadisurya, Elizabeth G. Porter, W. Andy Tao, et al. (2025). PBRM1-Dependent PBAF Targeting is Required for EMT and Metastasis in Breast Cancer .