プロフィール詳細

プロジェクトを作成

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Dr. Hazrat B.に依頼

Singapore

Ph.D. Biochemist | Microbiologist | Microbiome, Metabolomics & Cardiometabolic Disease Researcher | GLP/GMP QA/QC Expert

プロフィール概要

Ph.D. Biochemist, Microbiologist, and Molecular Biologist specializing in host-microbiome metabolic interactions, microbial metabolite signaling, and systemic tissue resilience. I use integrated 16S rRNA sequencing and metabolomics to decipher how microbial-derived small molecules modulate host physiology, with doctoral research demonstrating how Sodium Butyrate mitigates cardiac injury by restoring gut barrier integrity and modulating HIF-1α/SERCA2a-linked calcium homeostasis. My work has resulted in SCI-published findings (PeerJ, Scientific Reports, MDPI, Wiley) and several manuscripts under review. I combine advanced in vivo and in vitro experimental research (RT-qPCR, Western blotting, siRNA knockdown, confocal imaging, rodent disease modeling) with bioinformatics pipelines (QIIME2, DESeq2, MetaboAnalyst, R-Studio) and over a decade of pharmaceutical microbiology and QA/QC expertise under strict GLP/GMP compliance. I also bring collegiate lecturing experience, an active Mentorship Certificate, and a track record of training graduate students and lab technicians. I'm available for projects in multi-omics data analysis, microbiome/metabolomics research design, manuscript writing and review, GLP/GMP/QA-QC consulting, SOP authoring, and cleanroom/biosafety auditing.

専門分野

• ☆ Microbiology
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Omics
• ☆ Metabolomics
• ☆ Food Microbiology
• ☆ R
• ☆ In vitro Diagnostics
• ☆ Biomarker Analysis
• ☆ Pharmaceutical Management
• ☆ Stability Testing
• ☆ Quality Assurance & Quality Control (QA/QC)
• ☆ Medical Writing
• ☆ Medical Content Writing
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Creative Writing
• ☆ Cosmetic & Skincare Formulation
• ☆ Personal Care Product Formulation
• ☆ Cosmetic & Personal Care Product Manufacturing
• ☆ Herbal Products
• ☆ Nutraceuticals
• ☆ Supplements
• ☆ Consumer Products

サービス

• Writing
• Research
• Data & AI
• Product Development

Writing Medical Writing

Research Meta-Research

Data & AI Statistical Analysis, Data Visualization

Product Development Formulation, Stability/Shelf Life Testing

職務経験

Microbiome, Metabolomics & QA/QC Consultant

Independent Scientific Consultant

7月 2019 - 現在

Ph.D. Researcher and Graduate Research Mentor

Dalian Medical University

9月 2020 - 6月 2026

Visiting Lecturer and Biology Laboratory Supervisor

LMC

9月 2017 - 8月 2020

Microbiology Laboratory In-Charge

Pharmaceutical Laboratories

9月 2017 - 6月 2019

Senior Microbiologist, Quality Control

Roomi Enterprises (Toothpastes, mouth washes, cosmetics, Sensodyne/GSK)

11月 2015 - 8月 2017

Microbiologist

Macter International Limited

6月 2014 - 11月 2015

QC/QA Incharge

Al-Khair Creative Quality Wares (agri food, oral care & cosmetics)

9月 2013 - 5月 2014

Clinical Microbiologist

Dr. Essa Laboratory and Diagnostic Centre

2月 2013 - 8月 2013

学歴

Ph.D Biochemistry and Molecular Biology

Dalian Medical University, China

9月 2020 - 6月 2026

Master Microbiology

University of Karachi

1月 2011 - 12月 2012

認定資格

• Mentorship Certificate

  Dalian Medical University

  5月 2026 - 現在

• Investigations and CAPA

  Ciné-Med (US FDA-funded)

  12月 2021 - 現在

• BioSafe360

  PBSA & Safer Behaviors USA

  12月 2021 - 現在

• USP Raw Materials for Manufacturing of Biologics

  The United States Pharmacopeia

  6月 2021 - 現在

• Bioanalytical Method Validation

  US FDA

  6月 2019 - 現在

• Advanced Molecular Biology Intensive Training

  Aga khan University hospital

  10月 2016 - 現在

出版物

JOURNAL ARTICLE

Hazrat Bilal, Xiao Yu, Xuexue Liu, Jian Zhao, Xiaopeng Zhang, Wei Song, Xin Kong, Rui Zhang, Jianrong Bao, Mingxiu Dai, et al. (2026). Post-infarction KLHL40-mediated regulation of cardiac sarcomeric integrity and function . PeerJ.

Hazrat Bilal, Imran Khan, Ayesha Yaseen, Xiaopeng Zhang, Xuexue Liu, Jian Zhao, Jing Li, Ata Ur Rehman, Lei Sun, Xiao Yu (2026). Sodium Butyrate Attenuates Isoprenaline-Induced Myocardial Injury via Restoring the Gut–Heart Axis and Suppressing TLR4/NF-κB Signaling . Current Issues in Molecular Biology.

Hazrat Bilal, Imran Khan, Ayesha Yaseen, Xiaopeng Zhang, Xuexue Liu, Jian Zhao, Jing Li, Ata Ur Rehman, Lei Sun, Xiao Yu (2026). Sodium Butyrate Attenuates Isoprenaline-Induced Myocardial Injury via Restoring the Gut–Heart Axis and Suppressing TLR4/NF-κB Signaling . Current Issues in Molecular Biology.

Wang Y, Li J, Bilal H, Yu X, Sun L (2025). The Rising Tide of Coronary Crisis: Decoding Age-Specific Disparities in Ischemic Heart Disease Burden Through the Global Burden of Disease Study 2021 Revelations: An Ecological Study . Health science reports.

Hazrat Bilal, Xiao Yu, Xiaopeng Zhang, Chang Shi, Lei Sun (2025). Exploring potential biomarkers for acute myocardial infarction by combining circadian rhythm gene expression and immune cell infiltration . Scientific Reports.

Hazrat Bilal, Ata Ur Rehman, Asif Iqbal Khan, Tian Zhiying, Xiaoxiao Zhang, Wen Yuqi, Duaa Mohammad Abdallah Alsholi, Yi Xin, Liang Wang (2022). Morchella esculenta Polysaccharide Attenuates Obesity through Ameliorating Adipose and Liver Tissue Inflammation in Obese Mouse Model . Journal of Biomedical Research & Environmental Sciences.

Bilal, H., Khan, I., Yaseen, A., Zhang, X., Liu, X., Zhao, J., Li, J., Rehman, A. U., Sun, L., & Yu, X. (2026). Sodium Butyrate Attenuates Isoprenaline-Induced Myocardial Injury via Restoring the Gut–Heart Axis and Suppressing TLR4/NF-κB Signaling. Current Issues in Molecular Biology, 48(5), 501. https://doi.org/10.3390/cimb48050501 .