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プロフィール詳細
Dr. Iain H.に依頼
United Kingdom
Structural Biology | Protein Biochemistry | Cell & Mol. bio | 10+ years academic research & publishing
プロフィール概要
専門分野
サービス
Research
Fact Checking,
Scientific and Technical Research,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
職務経験
Postdoctoral Research Scientist
MRC Laboratory of Molecular Biology
4月 2022 - 現在 ![]()
Postdoctoral Research Scientist
Babraham Institute
4月 2021 - 3月 2022 ![]()
学歴
PhD (Cambridge Institute for Medical Research)
UNIVERSITY OF CAMBRIDGE
10月 2016 - 4月 2021 ![]()
MRes Medical Science
UNIVERSITY OF CAMBRIDGE
10月 2016 - 9月 2017
BSc (Hons) Molecular and Cellular Biology
University of Glasgow
9月 2011 - 7月 2016
認定資格
出版物
PREPRINT
Iain M. Hay, Maxime Bourguet, Bilal Ahsan, Olga Perisic, Madhangopal Anandapadamanaban, Roger L. Williams (2026). Structural basis for a phosphoinositide-driven mTORC2-AKT positive feedback loop .
Clarissa N. Pacyna, Madhanagopal Anandapadamanaban, Kevin W. Loudon, Iain M. Hay, Olga Perisic, Ruoyan Li, Matthew Byrne, Laura Allen, Kirsty Roberts, Yvette Hooks, et al. (2023). Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis .
Iain M. Hay, Maria Shamin, Eve R. Caroe, Ahmed S. A. Mohammed, Dmitri I. Svergun, Cy M. Jeffries, Stephen C. Graham, Hayley J. Sharpe, Janet E. Deane(2022). Determinants of receptor tyrosine phosphatase homophilic adhesion: structural comparison of PTPRK and PTPRM extracellular domains . Cold Spring Harbor Laboratory
Iain M. Hay, Katie E. Mulholland, Stephen C. Graham, Hayley J. Sharpe, Janet E. Deane(2022). Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain . Cold Spring Harbor Laboratory
JOURNAL ARTICLE
Iain M. Hay, Maria Shamin, Eve R. Caroe, Ahmed S.A. Mohammed, Dmitri I. Svergun, Cy M. Jeffries, Stephen C. Graham, Hayley J. Sharpe, Janet E. Deane (2023). Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains . Journal of Biological Chemistry.
The receptor PTPRU is a redox sensitive pseudophosphatase <head>
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</head> . Nature Communications.
Fearnley GW, Young KA, Edgar JR, Antrobus R, Hay IM, Liang WC, Martinez-Martin N, Lin W, Deane JE, Sharpe HJ(2019). The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion . eLife.
OTHER
Iain M. Hay, Gareth W. Fearnley, Pablo Rios, Maja Köhn, Hayley J. Sharpe, Janet E. Deane(2019). The receptor PTPRU is a redox sensitive pseudophosphatase . Cold Spring Harbor Laboratory