プロフィール詳細

プロジェクトを作成

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Dr. Ilario D.に依頼

Spain

I am an expert in the analysis of omics data, I worked both in academia, bioinformatics consultancy and big pharmas.

プロフィール概要

Senior Bioinformatician with 10 years of experience in the analysis of omics data, mainly in the fields of neurosciencde, inflammation, and oncology. I have worked both in academia (in center of excellence in Italy, France, and Spain) and in bioinformatics consultancy (Sequentia Biotech and Clarivate). I am actually Senior Scientist in the department of oncology data science in AZ. Skills: bioinformatics: transcriptomics (microarray, bulk and single cell RNA-seq), epigenetics (ChIP-seq and Cut&Run), genomics, proteomics, data visualization (creation o web application and interactive reports), machine learning (classification and prediction throught statistical models and random forest), integration (knowledge graph), downstream analusis (overrepresentation analysis, GSEA, WGCNA) Programming: R, python, shell, SQL Languages: Italian (native); English and Spanish (advanced); French (intermediate); Catalan (elementary)

専門分野

• ★ Transcriptomics
• ★ RNA Sequencing
• ★ Gene & Protein Expression Analysis
• ☆ Molecular Biology
• ☆ Omics
• ☆ Proteomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ ChIP-Seq
• ☆ Neuroscience
• ☆ Computational Neuroscience
• ☆ Cognitive Neuroscience
• ☆ Bioinformatics

サービス

• Writing
• Consulting
• Data & AI

Writing Technical Writing, General Proofreading & Editing, Translation

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

職務経験

Senior Scientist

AstraZeneca

5月 2023 - 現在

Senior Bioinformatician

Sequentia Biotech

8月 2022 - 5月 2023

Senior postdoctoral scientist

Imim

2月 2021 - 7月 2022

Predoctoral fellow

Institute Curie

10月 2011 - 4月 2022

Senior Postdoc

Center for Genomic Regulation

1月 2016 - 1月 2021

PostdoctoralResearcher

IRCCS San Donato, San Donato Milanese, Italy

6月 2016 - 12月 2016

PhD Fellow

Università Vita Salute San Raffaele

4月 2012 - 6月 2015

学歴

PhD in Molecular Medicine

Università Vita-Salute San Raffaele

4月 2012 - 6月 2015

Medical Biotechnolgy and Molecular Medicine

Università degli Studi di Bari

10月 2008 - 10月 2010

Pharmaceutical Biotechnology

Università degli Studi di Bari

10月 2005 - 7月 2008

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Hosseini, E., Bagheri-Hosseinabadi, Z., De Toma, I., Jafarisani, M., Sadeghi, I.(2019). The importance of long non-coding RNAs in neuropsychiatric disorders . Molecular Aspects of Medicine.

Olesti, E., De Toma, I., Ramaekers, J.G., Brunt, T.M., Carbó, M., Fernández-Avilés, C., Robledo, P., Farré, M., Dierssen, M., Pozo, Ó.J., et al.(2019). Metabolomics predicts the pharmacological profile of new psychoactive substances . Journal of Psychopharmacology. 33. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 347-354.

(2018). Overweighed mice show coordinated homeostatic and hedonic transcriptional response across brain . eneuro.

Olesti E, De Toma I, Ramaekers JG, Brunt TM, Carbó ML, Fernández-Avilés C, Robledo P, Farré M, Dierssen M, Pozo ÓJ, et al.(2018). Metabolomics predicts the pharmacological profile of new psychoactive substances . Journal of psychopharmacology (Oxford, England).

Faundez V, De Toma I, Bardoni B, Bartesaghi R, Nizetic D, de la Torre R, Cohen Kadosh R, Herault Y, Dierssen M, Potier MC, et al.(2018). Translating molecular advances in Down syndrome and Fragile X syndrome into therapies . European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.

De Toma, I., Grabowicz, I.E., Fructuoso, M., Trujillano, D., Wilczyński, B., Dierssen, M.(2018). Overweight mice show coordinated homeostatic and hedonic transcriptional response across brain . eNeuro. 5. (6).

Faundez, V., De Toma, I., Bardoni, B., Bartesaghi, R., Nizetic, D., de la Torre, R., Cohen Kadosh, R., Herault, Y., Dierssen, M., Potier, M.-C., et al.(2018). Translating molecular advances in Down syndrome and Fragile X syndrome into therapies . European Neuropsychopharmacology. 28. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 675-690.

Toma ID, Gil LM, Ossowski S, Dierssen M(2016). Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders . Neural plasticity.

Voellenkle C, Garcia-Manteiga JM, Pedrotti S, Perfetti A, De Toma I, Da Silva D, Maimone B, Greco S, Fasanaro P, Creo P, et al.(2016). Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing . Scientific reports.

Zambrano S, De Toma I, Piffer A, Bianchi ME, Agresti A, eLife, 2016, vol. 5 .

Toma, I.D., Gil, L.M., Ossowski, S., Dierssen, M.(2016). Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders . Neural Plasticity. 2016.

Zambrano, S., de Toma, I., Piffer, A., Bianchi, M.E., Agresti, A.(2016). NF-κB oscillations translate into functionally related patterns of gene expression . eLife. 5. (JANUARY2016).

Voellenkle, C., Garcia-Manteiga, J.M., Pedrotti, S., Perfetti, A., De Toma, I., Da Silva, D., Maimone, B., Greco, S., Fasanaro, P., Creo, P., et al.(2016). Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing . Scientific Reports. 6.

De Toma I, Rossetti G, Zambrano S, Bianchi ME, Agresti A, Journal of internal medicine, 2014, vol. 276, no. 5, pp. 454-469 .

De Toma, I., Rossetti, G., Zambrano, S., Bianchi, M.E., Agresti, A.(2014). Nucleosome loss facilitates the chemotactic response of macrophages . Journal of Internal Medicine. 276. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 454-469.