プロフィール詳細

プロジェクトを作成

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Dr. Indrabahadur S.に依頼

Germany

Emmy Noether Independent Group Leader at DKFZ German Cancer Research Center

プロフィール概要

Hello everybody, I am Senior Scientist at German Cancer Research Center (DKFZ), Heidelberg, Germany and editorial board member of SM Journal of Bioprocessing and Biotechniques. I have more than 10 years of research experience in the field of biomedical research supported by several high profile research articles (e.g. Singh I et al 2018 Nature Genetics, Singh I et al 2015 Cell Research, Singh I et al 2014 BMC Biology,...) and patents. In addition, I am also MBA degree holder that further strengthen my extensive R&D experience in biomedical project and project portfolio management credentials. Specialties: * Project and Project portfolio management * RNA biology * Epigenetics * Molecular Embryology * Lung fibrosis * Anticancer drug screening and cancer diagnostic tool development. * Tumorigenesis * Mammalian Cell culture * Pre-clinical Mouse models I am here to offer significant value to businesses that are seeking to solve complex issues. I enjoy consulting, coaching and mentoring. If you are seeking solutions and still looking for it :( Feel comfortable to contact me at indraiitr [at] gmail.com :) My best wishes, Indra

専門分野

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Epigenetics
• ☆ RNA Sequencing
• ☆ Stem Cell Research
• ☆ Cell Culture
• ☆ Information & Knowledge Management
• ☆ Experiential Education
• ☆ Science Education
• ☆ Technology Education
• ☆ German
• ☆ Pharmacogenomics
• ☆ Clinical Trials
• ☆ Gastroenterology & Hepatology
• ☆ Clinical Laboratory Science
• ☆ Pulmonology/Respiratory Disease
• ☆ Rare Diseases
• ☆ Healthcare Administration & Management
• ☆ Hospital & Medical Facility Management
• ☆ Medical Practice Management
• ☆ Stress Management
• ☆ Business Education
• ☆ Management
• ☆ Innovation Management

サービス

• Research

Research Market Research, Feasibility Study

職務経験

Emmy Noether Independent Research Group Leader

German Cancer Research Center

10月 2019 - 現在

Emmy Noether Independent Research Group Leader

German Cancer Research Center

10月 2019 - 現在

Senior Scientist

German Cancer Research Center

2月 2018 - 9月 2019

Post-Doc Scientist

Max Planck Institute for Heart and Lung Research

5月 2014 - 12月 2017

学歴

MBA (THM Business School)

University of Applied Sciences Mittelhessen

10月 2014 - 8月 2016

Dr. rer. nat. (Biochemistry, Genetics, Pulmonary Pharmacotherapy and Molecular Genetics)

Justus-Liebig-Universität Giessen

4月 2011 - 9月 2014

Dr. rer. nat. (Lung Cancer Epigenetics)

Max Planck Institute for Heart and Lung Research

12月 2009 - 9月 2014

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2019). Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis . Nature communications.

(2019). A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cellular and Molecular Life Sciences.

Singh I, Contreras A, Cordero J, Rubio K, Dobersch S, Günther S, Jeratsch S, Mehta A, Krüger M, Graumann J, et al.(2018). MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization . Nature genetics.

Mehta A, Cordero J, Dobersch S, Romero-Olmedo AJ, Savai R, Bodner J, Chao CM, Fink L, Guzmán-Díaz E, Singh I, et al.(2016). Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate . EMBO molecular medicine.

Ilinskaya ON, Singh I, Dudkina E, Ulyanova V, Kayumov A, Barreto G(2016). Direct inhibition of oncogenic KRAS by Bacillus pumilus ribonuclease (binase) . Biochimica et biophysica acta.

Singh I, Ozturk N, Cordero J, Mehta A, Hasan D, Cosentino C, Sebastian C, Krüger M, Looso M, Carraro G, et al.(2015). High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX . Cell research.

Ozturk N, Singh I, Mehta A, Braun T, Barreto G(2014). HMGA proteins as modulators of chromatin structure during transcriptional activation . Frontiers in cell and developmental biology.

Singh I, Mehta A, Contreras A, Boettger T, Carraro G, Wheeler M, Cabrera-Fuentes HA, Bellusci S, Seeger W, Braun T, et al.(2014). Hmga2 is required for canonical WNT signaling during lung development . BMC biology.

(2014). Transformed lung epithelial cells produce microbial RNAse (binase) . Genes and Cells. 9. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 63-67.

(2013). Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling . Journal of proteome research.

CONFERENCE PAPER

(2019). Dysregulated epigenetic factors in non-alcoholic fatty liver disease and triggered liver cancer .

(2017). HMGA2 mediated epigenetic regulation of Gata6 controls epithelial WNT signalling during lung development .

(2017). Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate .

(2017). Nuclear miRNA/exosome-mediated transcriptional silencing within the context of TGFB1 signaling and Idiopathic Pulmonary Fibrosis .

PATENT

(2014). Isoforms of gata6 and nkx2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy .