プロフィール詳細

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Irene P.に依頼

Italy

Pharmacologist & Medical Writer, Precision Medicine, nutraceuticals, Pharmacogenomics, longevity science

プロフィール概要

Irene Palenca, PhD – Pharmacologist | Biomedical Consultant | Scientific Writer I’m a pharmacologist with a PhD in pharmacology, currently working in academic research and biotech innovation with a focus on precision medicine, pharmacogenomics, and advanced nutraceuticals. I specialize in translating complex biomedical data into actionable insights for product development, scientific communication, and regulatory strategy. As a registered pharmacist with a strong background in molecular biology, I support supplement, pharma, and cosmetic companies in designing evidence-based formulations, biomarker-driven strategies, and clear, compelling content for both scientific and commercial audiences. Core services: • Nutraceutical and cosmetic formulation consulting • Pharmacogenomic and biomarker project development • Scientific and regulatory writing (ENG/ITA) • Literature reviews, white papers, product monographs • Education and training content for health professionals

専門分野

• ☆ Pharmacy
• ☆ Pharmacy Education
• ☆ Drug Development
• ☆ Biosafety Testing
• ☆ Microbiology Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Drug Efficacy Testing
• ☆ Preventive Medicine
• ☆ Precision Medicine
• ☆ Gastroenterology & Hepatology
• ☆ Colorectal Cancer
• ☆ Crohn's Disease
• ☆ Irritable Bowel Syndrome (IBS)
• ☆ Pain Management
• ☆ Inflammation
• ☆ Pharmaceutical Management
• ☆ Medical Writing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Technical Writing, General Proofreading & Editing, Translation

Research Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Data Processing

Product Development Formulation, Recipe Development, Stability/Shelf Life Testing, Product Evaluation, Product Validation, Concept Development

職務経験

R&D Manager

Farmagens Healthcare

1月 2025 - 現在

学歴

Master Degree in Pharmacy

University of Rome La Sapienza

10月 2015 - 10月 2020

認定資格

• PhD in pharmacology and toxycology

  University of Rome La Sapienza

  1月 2025 - 現在

出版物

JOURNAL ARTICLE

Irene Palenca, Vandna Sharma, Valentina Noemi Madia, Valeria Tudino, Jennifer V. Nguyen, Anjan Debnath, Antonella Messore, Davide Ialongo, Elisa Patacchini, Silvia Basili Franzin, et al. (2023). Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors . Journal of Medicinal Chemistry.

Irene Palenca, Luisa Seguella, Aurora Zilli, Silvia Basili Franzin, Alessandro Del Re, Federico Pepi, Anna Troiani, Marcella Pesce, Sara Rurgo, Fatima Domenica Elisa De Palma, et al. (2023). Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients . International Journal of Molecular Sciences.

irene palenca, LUISA SEGUELLA, Aurora Zilli, Silvia Basili Franzin, Alessandro Del Re, federico pepi, Anna Troiani, Marcella Pesce, Sara Rurgo, Fatima De Palma, et al. (2023). Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients . International Journal of Molecular Sciences.

Irene Palenca, Giovanni Sarnelli, Alessandro Del Re, Marcella Pesce, Jie Lu, Giovanni Esposito, Walter Sanseverino, Chiara Corpetti, Silvia Basili Franzin, Luisa Seguella, et al. (2023). Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice . Biomolecules.

irene palenca, Giovanni Sarnelli, Alessandro Del Re, Marcella Pesce, Jie Lu, Giovanni Esposito, Walter Sanseverino, Chiara Corpetti, Silvia Basili Franzin, LUISA SEGUELLA, et al. (2023). Oral Immunization with <i>Escherichia coli Nissle 1917</i> Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice . Biomolecules.

Irene Palenca, Luisa Seguella, Alessandro Del Re, Silvia Basili Franzin, Chiara Corpetti, Marcella Pesce, Sara Rurgo, Luca Steardo, Giovanni Sarnelli, Giuseppe Esposito (2022). N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism . Biomolecules.

irene palenca, LUISA SEGUELLA, Alessandro Del Re, Silvia Basili Franzin, Chiara Corpetti, Marcella Pesce, Sara Rurgo, Luca Steardo, Giovanni Sarnelli, Giuseppe Esposito (2022). N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism . Biomolecules.

Irene Palenca, Alessandro Del Re, Luisa Seguella, Marcella Pesce, Chiara Corpetti, Luca Steardo, Sara Rurgo, Giovanni Sarnelli, Giuseppe Esposito(2022). Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action . Metabolites. 12. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 457. {MDPI} {AG}

Irene Palenca, Marcella Pesce, Luisa Seguella, Alessandro Del Re, Jie Lu, Chiara Corpetti, Sara Rurgo, Walter Sanseverino, Giovanni Sarnelli, Giuseppe Esposito(2022). Next-Generation Probiotics for Inflammatory Bowel Disease . International Journal of Molecular Sciences. 23. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5466. {MDPI} {AG}

irene palenca, Alessandro Del Re, LUISA SEGUELLA, Marcella Pesce, Chiara Corpetti, Luca Steardo, Sara Rurgo, Giovanni Sarnelli, Giuseppe Esposito (2022). Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action . Metabolites.

irene palenca, Marcella Pesce, LUISA SEGUELLA, Alessandro Del Re, Jie Lu, Chiara Corpetti, Sara Rurgo, Walter Sanseverino, Giovanni Sarnelli, Giuseppe Esposito (2022). Next-Generation Probiotics for Inflammatory Bowel Disease . International Journal of Molecular Sciences.

Irene Palenca, Barbara De Conno, Marcella Pesce, Martina Chiurazzi, Marta Andreozzi, Sara Rurgo, Chiara Corpetti, Luisa Seguella, Alessandro Del Re, Giuseppe Esposito, et al.(2022). Nutraceuticals and Diet Supplements in Crohn’s Disease: A General Overview of the Most Promising Approaches in the Clinic . Foods. 11. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1044. {MDPI} {AG}

irene palenca, Barbara De Conno, Marcella Pesce, Martina Chiurazzi, Marta Andreozzi, Sara Rurgo, Chiara Corpetti, Luisa Seguella, Alessandro Del Re, Giuseppe Esposito, et al. (2022). Nutraceuticals and Diet Supplements in Crohn&rsquo;s Disease: A General Overview of the Most Promising Approaches in the Clinic . Foods.