プロフィール詳細

プロジェクトを作成

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Dr. Jacob B.に依頼

United States

Computational Biologist & Bioinformatics Consultant (Ph.D. Neuroscience) | Single-cell, Multi-omics, Image Analysis | R

プロフィール概要

I am a computational biologist and bioinformatics scientist with expertise in RNA sequencing (bulk, single-cell, spatial, nuclei), proteomics, imaging, and multi-omics integration. I specialize in developing custom analysis pipelines, interactive applications, and machine learning workflows that accelerate drug discovery and reverse translation. With a Ph.D. in Neuroscience and experience across academia, biotech, and pharma, I’ve published 24 scientific papers (9 first-author) and developed VesselVio, an open-source vascular image analysis application featured in Cell Reports Methods. My work bridges discovery research and clinical development by delivering actionable insights from high-dimensional biological datasets. I offer end-to-end support: from experimental design and quality control to statistical analysis, visualization, and interactive tool development. Whether you need targeted analyses, custom workflow development, or strategic insights, I bring a track record of rigor, speed, and clarity.

専門分野

• ☆ Biostatistics
• ☆ Data Analysis
• ☆ Image Processing
• ☆ Algorithm Design
• ☆ Predictive Modeling & Analytics
• ☆ Data Processing
• ☆ Data Exploration
• ☆ Cluster Analysis
• ☆ Data Visualization
• ☆ Big Data Analytics
• ☆ Data Collection
• ☆ Data Management
• ☆ Data Manipulation
• ☆ Machine Learning
• ☆ Data Mining
• ☆ Data Cleaning
• ☆ Data Architecture
• ☆ Neural Networks
• ☆ Pattern Recognition
• ☆ Artificial Intelligence
• ☆ Deep Learning
• ☆ Computer Vision
• ☆ Statistics
• ☆ Regression Analysis
• ☆ Multivariate Analysis
• ☆ Nonlinear Regression
• ☆ Correlation Analysis
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Systems Biology
• ☆ Knowledge Management
• ☆ Information & Knowledge Management
• ☆ Data Storage
• ☆ Python
• ☆ SQL
• ☆ Tensorflow
• ☆ R
• ☆ Scikit-learn
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ High Content Screening/Imaging
• ☆ Pharmaceutical Technology
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Fact Checking
• ☆ Literature Search

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, General Proofreading & Editing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

職務経験

Scientist

Bristol-Myers Squibb

9月 2023 - 現在

学歴

PhD Neuroscince

West Virginia University

8月 2019 - 7月 2023

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Jacob R. Bumgarner, William H. Walker, II, Dominic D. Quintana, Rhett C. White, Alexandra A. Richmond, O. Hecmarie Meléndez-Fernández, Jennifer A. Liu, Darius D. Becker-Krail, James C. Walton, James W. Simpkins, et al. (2023). Acute exposure to artificial light at night alters hippocampal vascular structure in mice . iScience.

Jennifer A. Liu, James C. Walton, Jacob R. Bumgarner, William H. Walker, II, O. Hecmarie Meléndez-Fernández, A. Courtney DeVries, Randy J. Nelson (2022). Chronic exposure to dim light at night disrupts cell-mediated immune response and decreases longevity in aged female mice . Chronobiology International.

Jacob R. Bumgarner, Randy J. Nelson (2022). Open-source analysis and visualization of segmented vasculature datasets with VesselVio . Cell Reports Methods.

Jacob R Bumgarner, Randy J Nelson(2021). Light at Night and Disrupted Circadian Rhythms Alter Physiology and Behavior . Integrative and Comparative Biology. 61. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1160--1169. Oxford University Press ({OUP})

Jacob R. Bumgarner, William H. Walker, II, Randy J. Nelson (2021). Circadian rhythms and pain . Neuroscience & Biobehavioral Reviews.

William H. Walker, II, Raegan M. Kvadas, Laura E. May, Jennifer A. Liu, Jacob R. Bumgarner, James C. Walton, A. Courtney DeVries, Robert T. Dauchy, David E. Blask, Randy J. Nelson(2021). Artificial Light at Night Reduces Anxiety-like Behavior in Female Mice with Exacerbated Mammary Tumor Growth . Cancers. 13. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4860. {MDPI} {AG}

William H. Walker, Raegan M. Kvadas, Laura E. May, Jennifer A. Liu, Jacob R. Bumgarner, James C. Walton, A. Courtney DeVries, Robert T. Dauchy, David E. Blask, Randy J. Nelson (2021). Artificial Light at Night Reduces Anxiety-like Behavior in Female Mice with Exacerbated Mammary Tumor Growth . Cancers.

Randy J. Nelson, Jacob R. Bumgarner, William H. Walker, II, A. Courtney DeVries (2021). Time-of-day as a critical biological variable . Neuroscience & Biobehavioral Reviews.

William H. Walker, II, Jacob R. Bumgarner, James C. Walton, Jennifer A. Liu, O. Hecmarie Meléndez-Fernández, Randy J. Nelson, A. Courtney DeVries (2020). Light Pollution and Cancer . International Journal of Molecular Sciences.

William H. Walker, Jacob R. Bumgarner, James C. Walton, Jennifer A. Liu, O. Hecmarie Meléndez-Fernández, Randy J. Nelson, A. Courtney DeVries (2020). Light Pollution and Cancer . International Journal of Molecular Sciences.

Zachary M. Weil, Laura K. Fonken, William H. Walker, II, Jacob R. Bumgarner, Jennifer A. Liu, O. Hecmarie Melendez‐Fernandez, Ning Zhang, A. Courtney DeVries, Randy J. Nelson (2020). Dim light at night exacerbates stroke outcome . European Journal of Neuroscience.

(2020). Circadian Variation in Efficacy of Medications . Clinical pharmacology and therapeutics.

(2020). Dim Light at Night Exposure Induces cold Hyperalgesia and Mechanical Allodynia in Male Mice . Neuroscience.

William H. Walker, II, Jacob R. Bumgarner, Randy J. Nelson, A. Courtney DeVries(2020). Transcardial perfusion is not required to accurately measure cytokines within the brain . Journal of Neuroscience Methods. 334. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 108601. Elsevier {BV}

(2020). Transcardial Perfusion is not Required to Accurately Measure Cytokines within the Brain . Journal of Neuroscience Methods.

Sprowls, S.A., Arsiwala, T.A., Bumgarner, J.R., Shah, N., Lateef, S.S., Kielkowski, B.N., Lockman, P.R.(2019). Improving CNS Delivery to Brain Metastases by Blood–Tumor Barrier Disruption . Trends in Cancer. 5. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 495-505.

OTHER

Jacob Bumgarner, Randy Nelson (2021). A Novel and Open-Source Application for Vasculature Dataset Analysis and Visualization .