プロフィール詳細

プロジェクトを作成

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Dr. Jane H.に依頼

United Kingdom

Molecular genetics expert and next generation sequencing specialist

プロフィール概要

Dynamic Molecular Genetics Scientist with over 10 years of postdoctoral experience, including 7 years in the pharmaceutical and biotechnology sectors. Expert in developing and implementing molecular diagnostics with a focus on Next Generation Sequencing (NGS), from experimental design through to data interpretation. Proven ability to drive innovation in biomarker discovery and molecular diagnostics. Strong communicator, adept at disseminating complex scientific concepts for both technical and non-technical audiences. Passionate about advancing healthcare through precision medicine.

専門分野

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Omics
• ☆ Genomics
• ☆ Epigenetics
• ☆ DNA Sequencing
• ☆ Women's Health
• ☆ Ovarian Cancer
• ☆ Oncology
• ☆ Clinical Laboratory Science
• ☆ Molecular Pathology
• ☆ Medical Sciences
• ☆ Technical & Scientific Writing
• ☆ Science Communication

サービス

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing, General Proofreading & Editing

Research Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Product Development Stability/Shelf Life Testing, Product Evaluation, Product Validation, Concept Development, Product Launch Support, Packaging Design

職務経験

Field application scientist

biomodal Ltd (formerly Cambridge Epigenetix)

2月 2022 - 1月 2025

Field application scientist

Nonacus Ltd

7月 2019 - 1月 2022

Senior Bioscientist

AstraZeneca

6月 2017 - 6月 2019

Translational Scientist

Molecular Genetics Laboratory Great Ormond Street Hospital

5月 2016 - 6月 2017

PostdoctoralResearcher

University College London

9月 2014 - 4月 2016

Postdoctoral R&D Scientist

National Hospital for Neurology and Neurosurgery

9月 2013 - 9月 2014

学歴

PhD Molecular Genetics

University College London, University of London - United Kingdom

9月 2009 - 9月 2013

Molecular Pathology & Genomics

Barts Cancer Institute (Queen Mary University of London

9月 2008 - 9月 2009

Biomedical Sciences

London Metropolitan University

9月 2004 - 6月 2008

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Hayward, J., Chitty, L.S.(2018). Beyond screening for chromosomal abnormalities: Advances in non-invasive diagnosis of single gene disorders and fetal exome sequencing . Seminars in Fetal and Neonatal Medicine. 23. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 94-101.

Fassad, M.R., Shoemark, A., le Borgne, P., Koll, F., Patel, M., Dixon, M., Hayward, J., Richardson, C., Frost, E., Jenkins, L., et al.(2018). C11orf70 Mutations Disrupting the Intraflagellar Transport-Dependent Assembly of Multiple Axonemal Dyneins Cause Primary Ciliary Dyskinesia . American Journal of Human Genetics. 102. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 956-972.

Irving, S., Dixon, M., Fassad, M.R., Frost, E., Hayward, J., Kilpin, K., Ollosson, S., Onoufriadis, A., Patel, M.P., Scully, J., et al.(2018). Primary Ciliary Dyskinesia Due to Microtubular Defects is Associated with Worse Lung Clearance Index . Lung. 196. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 231-238.

et al.(2017). High prevalence of CCDC103 p.His154Pro mutation causing primary ciliary dyskinesia disrupts protein oligomerisation and is associated with normal diagnostic investigations . Thorax.

et al.(2017). X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3 . Nature communications.

et al.(2015). Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer . Journal of the National Cancer Institute.

(2015). Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population . Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Song, H., Dicks, E., Ramus, S.J., Tyrer, J.P., Intermaggio, M.P., Song, H., Dicks, E., Ramus, S.J., Tyrer, J.P., Intermaggio, M.P., et al.(2015). Contribution of germline mutations in the RAD51B, RAD51C, and RAD51D genes to ovarian cancer in the population . Journal of Clinical Oncology. 33. (26). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2901-2907.

et al.(2013). Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development . PLoS medicine.

Widschwendter, M., Rosenthal, A.N., Philpott, S., Rizzuto, I., Fraser, L., Hayward, J., Intermaggio, M.P., Edlund, C.K., Ramus, S.J., Gayther, S.A., et al.(2013). The sex hormone system in carriers of BRCA1/2 mutations: A case-control study . The Lancet Oncology. 14. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1226-1232.