プロフィール詳細

プロジェクトを作成

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Dr. Jiyuan Z.に依頼

Belize

PhD Scientist | Expert in Proteomics, Protein Purification & Structural Biology | 15+ Yrs Biomedical Research

プロフィール概要

I am a PhD-trained biomedical scientist with over 15 years of research experience in proteomics, protein purification, structural biology, and analytical biochemistry. My work has contributed to high-impact publications in Molecular Cell, Nature Communications, and PNAS, with recognized discoveries in membrane protein regulation and ion channel biology. I specialize in protein expression and purification, mass spectrometry-based proteomics, cryo-EM structural analysis, and biochemical assay development. I’ve successfully led NIH-funded projects, enriched multi-protein complexes from native tissues, and provided mechanistic insights through advanced analytical and molecular biology techniques. As a detail-oriented and collaborative researcher, I help clients solve complex biological problems, interpret experimental data, and develop robust methods for therapeutic protein characterization or basic research.

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Proteomics
• ☆ R

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing

Research Technology Scouting, Scientific and Technical Research

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

職務経験

Assistant Professor

The University of Texas Southwestern Medical Center

9月 2023 - 現在

Assistant Professor / Instructor

UT Southwestern Medical Center

6月 2020 - 現在

Instructor

University of Texas Southwestern Medical Center

5月 2020 - 9月 2023

Research Investigator / Postdoctoral Fellow

MD Anderson Cancer Center

4月 2013 - 3月 2020

Doctoral researcher/Research Assistant

Chinese Academy of Sciences

9月 2006 - 6月 2012

学歴

Postdoctoral fellow (Anesthesiology and peri-operative medicine)

University of Texas MD Anderson Cancer Center

4月 2013 - 10月 2018

PhD (Beijing Institute of Genomics)

Chinese Academy of Sciences

9月 2006 - 6月 2012

Ph.D. in Biochemistry

Chinese academy of sciences

9月 2006 - 6月 2012

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Jiyuan Zhang, Weizhong Zeng, Yan Han, Wan-Ru Lee, Jen Liou, youxing jiang (2023). Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel . Molecular Cell.

@article{Zhang_2020, doi = {10.1101/2020.05.21.109850}, url = {https://doi.org/10.1101%2F2020.05.21.109850}, year = 2020, month = {may}, publisher = {Cold Spring Harbor Laboratory}, author = {Jiyuan Zhang and Xin Guan and Jiusheng Yan}, title = {Lsm12 is an {NAADP} receptor and a two-pore channel regulatory protein required for calcium mobilization from acidic organelles}} .

(2018). Glutamate-activated BK channel complexes formed with NMDA receptors . Proceedings of the National Academy of Sciences of the United States of America.