プロフィール詳細

プロジェクトを作成

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Dr. John B.に依頼

United States

Aptamer, Food Safety/Microbiology/SBIR and Grant Writing Expert

プロフィール概要

Career Summary/Highlights: - Spearheaded acquisition/licensing of DNA Aptamer technology to ApolloDx and CibusDx. - Led team at Pronucleotein, Inc. which won 2nd Place (49 competitors) in the 2014 FDA Food Safety Testing Tech Challenge ($120K in total prize money;http://www.foodsafetychallenge.com/). - Launched a profitable DNA Aptamer sales website www.OTCBiotech.com. - Winner of the 2011 Small Business Administration’s Tibbetts Award for Excellence in SBIR R&D. - Awarded > 80 SBIR/STTR, other federal and state R & D contracts totaling > $20M. - Published 110 total peer-reviewed journal articles, 7 book chaps. & inventor on 16 issued US & EU patents. - Edited & contributed 3 chapters to a book entitled "Biomedical Applications of Aptamers,"​ Nova Science Publishers (formerly Plenum Press). - Patented a method for producing intrachain FRET-aptamers and assays - Patented and published a facile 3’ attachment chemistry to couple PCR products to proteins for low-cost industrial-scale mass production of DNA-3’-protein conjugates which are stable in vivo. - Invented and published DNA Aptamer-Complement conjugates to kill antibiotic-resistant infections (3 Patents Issued on Technology). - Invented and published DNA Aptamer-Fc opsonins to combat encapsulated pathogenic bacteria. - Developed & published DNA aptamer-based colloidal gold and fluorescent (nanoparticle and quantum dot-based) lateral flow test strips for the US Army to detect key hemorrhagic and other pathogenic viruses (e.g., Chikungunya, Crimean-Congo, Dengue, and West Nile viruses). - Developed an aptamer beacon assay for C-telopeptide (CTx) to monitor astronaut bone loss for NASA. Also developed N-acetylglucosamine and chitin aptamers to monitor recycled water aboard spacecraft for NASA under Phase 1 and Phase 2 SBIR contracts. - Invented and published novel FRET-Aptamer methodology and assays for bone markers, calcidiol, and organophosphorus nerve agent detection and quantification.

専門分野

• ★ Microbiology
• ☆ Molecular Engineering
• ☆ Immunoassay
• ☆ Molecular Biology
• ☆ Immunohistochemistry

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Gap Analysis, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Product Development Product Evaluation, Concept Development

職務経験

Director of Biotechnology

Nanohmics Inc

9月 2018 - 現在

Chief Science Officer

OTC Biotech/Pronucleotein

1月 2003 - 8月 2018

学歴

Doctorate

University of Arizona

8月 1986 - 5月 1991

認定資格

• Drug Development (including clinical trials and FDA approval)

  U.C. SanDiego

  11月 2019 - 現在

出版物

JOURNAL ARTICLE

Jeremy J. John, Christopher J. May, John G. Bruno(2021). A Combined Immunofluorescence and Fluorescent Viability Cocktail Staining Procedure for Rapid Microscopic Detection and Enumeration of Live Legionella pneumophila . Journal of Fluorescence. Springer Science and Business Media {LLC}

John G. Bruno(2019). Integration of multiple computer modeling software programs for characterization of a brain natriuretic peptide sandwich DNA aptamer complex . Journal of Molecular Recognition. 32. (12). Wiley