プロフィール詳細

プロジェクトを作成

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John R.に依頼

United States

PhD Immunologist | CAR-T, CAR-NK, T-Cell Engagers | Preclinical & Translational Immunotherapy Expert

プロフィール概要

I am a PhD-trained immunologist with 6+ years of industry experience leading preclinical and translational immunotherapy programs in oncology and autoimmunity. I have extensive hands-on and strategic expertise in CAR-T and CAR-NK development, T-cell engagers (BCMA/CD3, GPRC5D/CD3), and bispecific antibodies, advancing programs from discovery through IND-enabling development. I specialize in translating complex mechanistic data into actionable insights for internal teams, CROs, and external collaborators. My experience spans in vitro and in vivo modeling, including syngeneic, xenograft, and humanized mouse studies, autoimmune modeling, human immune cell profiling, and translational biomarker strategy. I have led cross-functional teams, guided preclinical study design, and supported portfolio prioritization, strategic investment decisions, and external collaborations. I am available for short-term consulting, advisory calls, and project-based engagements in immunotherapy development, preclinical strategy, and translational biomarker alignment.

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Stem Cell Research
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Primary Cells
• ☆ Cell Line Engineering
• ☆ Biomolecular Engineering
• ☆ Genetic Engineering
• ☆ Gene Editing/CRISPR
• ☆ Antibody Engineering
• ☆ Gene Delivery
• ☆ Cytometry
• ☆ Allergy & Clinical Immunology
• ☆ Clinical Immunology

サービス

• Research
• Consulting

Research Market Research, User Research, Meta-Research, Feasibility Study, Scientific and Technical Research

Consulting Operations Consulting, Scientific and Technical Consulting

職務経験

Founder / CEO

Rebel Bio

1月 2026 - 現在

Principal Scientist

Fate Therapeutics (United States)

5月 2019 - 8月 2025

学歴

PhD (Molecular Medicine - Cancer Biology)

University of Maryland, Baltimore

8月 2013 - 3月 2019

BS (Biology)

Saint Michael's College

2009 - 2013

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Moles MW, Erdlei H, Menzel L, Massaro M, Fiori A, Bunse M, Schrimpf M, Gerlach K, Gudipati V, Reiser J, et al. (2024). CXCR4 has a dual role in improving the efficacy of BCMA-redirected CAR-NK cells in multiple myeloma . Frontiers in immunology.

Reiser J, Sadashivaiah K, Furusawa A, Banerjee A, Singh N (2018). Eomesodermin driven IL-10 production in effector CD8+ T cells promotes a memory phenotype . Cellular immunology.

Furusawa A, Reiser J, Sadashivaiah K, Simpson H, Banerjee A (2018). Eomesodermin Increases Survival and IL-2 Responsiveness of Tumor-specific CD8+ T Cells in an Adoptive Transfer Model of Cancer Immunotherapy . Journal of immunotherapy (Hagerstown, Md. : 1997).

Reiser J, Banerjee A (2016). Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response . Journal of immunology research.