プロフィール詳細

プロジェクトを作成

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Kaleem I.に依頼

Saudi Arabia

Experienced Life Sciences Researcher | NGS · Bioinformatics · Data Analysis · Scientific Writing

プロフィール概要

I am a research professional specializing in cancer genetics and genomics, currently based at King Faisal Specialist Hospital and Research Center (KFSHRC), one of the region's leading academic medical institutions. My work sits at the intersection of wet lab science and computational analysis, giving me end-to-end experience across the research pipeline. Core expertise includes: Next-Generation Sequencing (NGS) and Whole Genome Sequencing (WGS) library preparation Oxford Nanopore Technologies (ONT) long-read sequencing Downstream bioinformatics pipeline development and analysis Data analysis | Statistics | R | high quality plots for publications Scientific writing for high-impact peer-reviewed journals. I have contributed as a co-author on peer-reviewed publications and have hands-on experience managing large-scale genomic datasets, including multi-terabyte sequencing runs. My work also encompasses procurement, regulatory compliance, and cross-functional collaboration with clinical and bioinformatics teams. Beyond the lab, I bring strong proficiency in scientific writing, data management, and research documentation — including NCCN-aligned clinical reporting and variant curation using databases such as ClinVar, COSMIC, TCGA, and cBioPortal. I am available to support projects involving genomic data analysis, scientific writing, literature review, bioinformatics consultation, and research methodology design.

専門分野

• ☆ Molecular Biology
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Genome Sequencing
• ☆ Exome Sequencing
• ☆ R
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ SOP & Protocol Writing
• ☆ Digital Marketing

サービス

• Writing
• Research
• Data & AI

Writing Technical Writing, General Proofreading & Editing

Research Scientific and Technical Research, Systematic Literature Review

Data & AI Statistical Analysis

職務経験

Research Assistant

King Faisal Specialist Hospital & Research Centre

7月 2017 - 現在

Research Trainee

King Khalid University Hospital

12月 2014 - 1月 2016

Research Assistant

Government College University, Lahore

11月 2013 - 11月 2014

学歴

MPhil (Institute of Industrial Biotechnology)

Government College University, Lahore

2012 - 2015

認定資格

• Cancer Biology

  John Hopkins University

  https://coursera.org/verify/specializat ion/LUV4S7H9D9R9

  7月 2025 - 現在

出版物

JOURNAL ARTICLE

Kaleem Iqbal, Rong Bu, Wael Haqawi, Eman A. Abdul Razzaq, Saud Azam, Zeeshan Qadri, Sandeep Kumar Parvathareddy, Maha Alrasheed, Khadija Alobaisi, Fouad Al-Dayel, et al. (2026). STK11 and DNA Repair Gene Mutations Define Hereditary Subset of Middle Eastern Papillary Thyroid Cancer . International Journal of Molecular Sciences.

Kaleem Iqbal, Rong Bu, Wael Haqawi, Eman A. Abdul Razzaq, Saud Azam, Zeeshan Qadri, Sandeep Kumar Parvathareddy, Maha Alrasheed, Khadija Alobaisi, Fouad Al-Dayel, et al. (2026). <i>STK11</i> and DNA Repair Gene Mutations Define Hereditary Subset of Middle Eastern Papillary Thyroid Cancer . International Journal of Molecular Sciences.

Kaleem Iqbal, Rong Bu, Sandeep Kumar Parvathareddy, Saud Azam, Zeeshan Qadri, Eman A. Abdul Razzaq, Fouad Al-Dayel, Abdul K. Siraj, Khawla S. Al-Kuraya (2026). Exome-Wide Association Analysis Identifies Rare Germline Susceptibility Variants in Early-Onset Breast Cancer Among Saudi Women . International Journal of Molecular Sciences.

Kaleem Iqbal, Rong Bu, Sandeep Kumar Parvathareddy, Saud Azam, Zeeshan Qadri, Eman A. Abdul Razzaq, Fouad Al-Dayel, Abdul K. Siraj, Khawla S. Al-Kuraya (2026). Exome-Wide Association Analysis Identifies Rare Germline Susceptibility Variants in Early-Onset Breast Cancer Among Saudi Women . International Journal of Molecular Sciences.

Kaleem Iqbal, Abdul Khalid Siraj, Rong Bu, Saud Azam, Zeeshan Qadri, Sandeep Kumar Parvathareddy, Fouad Al-Dayel, Khawla S. Al-Kuraya (2024). Whole Exome-Wide Association Identifies Rare Variants in APC Associated with High-Risk Colorectal Cancer in the Middle East . Cancers.

Kaleem Iqbal, Abdul Khalid Siraj, Rong Bu, Saud Azam, Zeeshan Qadri, Sandeep Kumar Parvathareddy, Fouad Al-Dayel, Khawla S. Al-Kuraya (2024). Whole Exome-Wide Association Identifies Rare Variants in <i>APC</i> Associated with High-Risk Colorectal Cancer in the Middle East . Cancers.

Kaleem Iqbal, Rong Bu, Abdul K. Siraj, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya (2023). Whole Exome-Wide Association Identifies Rare Variants in GALNT9 Associated with Middle Eastern Papillary Thyroid Carcinoma Risk . Cancers.

Kaleem Iqbal, Rong Bu, Abdul K. Siraj, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya (2023). Whole Exome-Wide Association Identifies Rare Variants in <i>GALNT9</i> Associated with Middle Eastern Papillary Thyroid Carcinoma Risk . Cancers.

Siraj, A.K., Bu, R., Parvathareddy, S.K., Iqbal, K., Azam, S., Qadri, Z., Al-Rasheed, M., Haqawi, W., Diaz, M., Victoria, I.G., et al.(2023). PALB2 germline mutations in a large cohort of Middle Eastern breast-ovarian cancer patients . Scientific Reports. 13. (1).

Lynch Syndrome Identification in Saudi Cohort of Endometrial Cancer Patients Screened by Universal Approach <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . International Journal of Molecular Sciences.

Kaleem Iqbal, Rong Bu, Abdul K. Siraj, Sandeep Kumar Parvathareddy, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Khadija Alobaisi, et al. (2022). Lynch Syndrome Identification in Saudi Cohort of Endometrial Cancer Patients Screened by Universal Approach . International Journal of Molecular Sciences.

Bu, R., Siraj, A.K., Parvathareddy, S.K., Iqbal, K., Azam, S., Qadri, Z., Al-Rasheed, M., Haqawi, W., Diaz, M., Alobaisi, K., et al.(2022). Lynch Syndrome Identification in Saudi Cohort of Endometrial Cancer Patients Screened by Universal Approach . International Journal of Molecular Sciences. 23. (20).

Siraj, A.K., Bu, R., Masoodi, T., Parvathareddy, S.K., Iqbal, K., Al-Haqawi, W., Al-Dossari, H., Azam, S., Qadri, Z., Annaiyappanaidu, P., et al.(2022). Exome sequencing revealed comparable frequencies of RNF43 and BRAF mutations in Middle Eastern colorectal cancer . Scientific Reports. 12. (1).

Parvathareddy, S.K., Siraj, A.K., Iqbal, K., Qadri, Z., Ahmed, S.O., Al-Rasheed, M., AlQatie, A.A., Al-Sobhi, S.S., Al-Dayel, F., Al-Kuraya, K.S.(2022). TERT Promoter Mutations Are an Independent Predictor of Distant Metastasis in Middle Eastern Papillary Thyroid Microcarcinoma . Frontiers in Endocrinology. 13.

Parvathareddy, S.K., Siraj, A.K., Bu, R., Iqbal, K., Al-Rasheed, M., Al-Haqawi, W., Annaiyappanaidu, P., Siraj, N., Ahmed, S.O., Al-Sobhi, S.S., et al.(2022). X-linked inhibitor of apoptosis protein (XIAP) predicts disease-free survival in BRAFV600E mutant papillary thyroid carcinoma in middle eastern patients . Frontiers in Endocrinology. 13.

Siraj, A.K., Masoodi, T., Bu, R., Parvathareddy, S.K., Iqbal, K., Azam, S., Al-Rasheed, M., Ajarim, D., Tulbah, A., Al-Dayel, F., et al.(2021). Prevalence of germline TP53 mutation among early onset middle eastern breast cancer patients . Hereditary Cancer in Clinical Practice. 19. (1).

Bu, R., Siraj, A.K., Masoodi, T., Parvathareddy, S.K., Iqbal, K., Al-Rasheed, M., Haqawi, W., Diaz, M., Victoria, I.G., Aldughaither, S.M., et al.(2021). Recurrent Somatic MAP2K1 Mutations in Papillary Thyroid Cancer and Colorectal Cancer . Frontiers in Oncology. 11.

Siraj, A.K., Bu, R., Iqbal, K., Parvathareddy, S.K., Masoodi, T., Siraj, N., Al-Rasheed, M., Kong, Y., Ahmed, S.O., Al-Obaisi, K.A.S., et al.(2020). POLE and POLD1 germline exonuclease domain pathogenic variants, a rare event in colorectal cancer from the Middle East . Molecular Genetics and Genomic Medicine. 8. (8).

Siraj, A.K., Bu, R., Arshad, M., Iqbal, K., Parvathareddy, S.K., Masoodi, T., Ghazwani, L.O., Al-Sobhi, S.S., Al-Dayel, F., Al-Kuraya, K.S.(2020). POLE and POLD1 pathogenic variants in the proofreading domain in papillary thyroid cancer . Endocrine Connections. 9. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 923-932.

Siraj, A.K., Bu, R., Iqbal, K., Parvathareddy, S.K., Siraj, N., Siraj, S., Diaz, M.R.F., Rala, D.R., Benito, A.D., Sabido, M.A., et al.(2020). Telomerase reverse transcriptase promoter mutations in cancers derived from multiple organ sites among middle eastern population . Genomics. 112. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1746-1753.

Kaleem Iqbal, Abdul K. Siraj, Poyil Pratheeshkumar, Sandeep Kumar Parvathareddy, Rong Bu, Tariq Masoodi, Maha Al-Rasheed, Fouad Al-Dayel, Saif S. Al-Sobhi, Ali S. Alzahrani, et al.(2019). Prognostic significance of DNMT3A alterations in Middle Eastern papillary thyroid carcinoma . European Journal of Cancer. 117. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 133--144. Elsevier {BV}

Kaleem Iqbal, Abdul K. Siraj, Rong Bu, Nabil Siraj, Wael Al‐Haqawi, Ismail A. Al‐Badawi, Sandeep Kumar Parvathareddy, Tariq Masoodi, Asma Tulbah, Fouad Al‐Dayel, et al.(2019). Prevalence, spectrum, and founder effect of BRCA1 and BRCA2 mutations in epithelial ovarian cancer from the Middle East . Human Mutation. 40. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 729--733. Wiley

Siraj, A.K., Bu, R., Iqbal, K., Siraj, N., Al-Haqawi, W., Al-Badawi, I.A., Parvathareddy, S.K., Masoodi, T., Tulbah, A., Al-Dayel, F., et al.(2019). Prevalence, spectrum, and founder effect of BRCA1 and BRCA2 mutations in epithelial ovarian cancer from the Middle East . Human Mutation. 40. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 729-733.

Siraj, A.K., Parvathareddy, S.K., Bu, R., Iqbal, K., Siraj, S., Masoodi, T., Concepcion, R.M., Ghazwani, L.O., Albadawi, I., Al-Dayel, F., et al.(2019). Germline POLE and POLD1 proofreading domain mutations in endometrial carcinoma from Middle Eastern region . Cancer Cell International. 19. (1).

Siraj, A.K., Pratheeshkumar, P., Parvathareddy, S.K., Bu, R., Masoodi, T., Iqbal, K., Al-Rasheed, M., Al-Dayel, F., Al-Sobhi, S.S., Alzahrani, A.S., et al.(2019). Prognostic significance of DNMT3A alterations in Middle Eastern papillary thyroid carcinoma . European Journal of Cancer. 117. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 133-144.

Akram, F., Haq, I.U., Khan, M.A., Hussain, Z., Mukhtar, H., Iqbal, K.(2016). Cloning with kinetic and thermodynamic insight of a novel hyperthermostable β-glucosidase from Thermotoga naphthophila RKU-10^T with excellent glucose tolerance . Journal of Molecular Catalysis B: Enzymatic. 124. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 92-104.

Haq, I., Akram, F., Khan, M.A., Hussain, Z., Nawaz, A., Iqbal, K., Shah, A.J.(2015). CenC, a multidomain thermostable GH9 processive endoglucanase from Clostridium thermocellum: cloning, characterization and saccharification studies . World Journal of Microbiology and Biotechnology. 31. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1699-1710.