プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Kempaiah R.に依頼

United States

Preclinical , IND, Vaccines & Biologics R&D, virology, Parasitology & bacterial diseases, Oncology Immunotherapy.

プロフィール概要

Ph.D. scientist with 20+ years of experience in infectious diseases, molecular biology, immunology, and vaccine development. I have led interdisciplinary programs involving DNA and viral vector platforms, immunotherapies, stable cell line development, and regulatory-compliant IND-enabling studies. My background includes extensive GLP/GCP-regulated preclinical research, assay development, bioanalytics, and translational program support. I bring strong expertise in project management, technology transfer, and strategic planning across biotech and pharmaceutical environments. I have recently founded Vaxonyx, a biotechnology startup at the HudsonAlpha Institute of Biotechnology focused on developing next-generation DNA device–free delivery platforms for vaccines, gene therapy, and immunotherapy, stable cell line, recombinant and native native antigen production. I am passionate about providing high-quality scientific consulting and helping organizations accelerate innovation in diagnostics, therapeutics, and vaccine development.

専門分野

• ☆ Microbiology
• ☆ Parasitology
• ☆ Virology
• ☆ Coronaviruses
• ☆ Noroviruses
• ☆ Zika Virus
• ☆ Cytomegaloviruses
• ☆ Adenoviruses
• ☆ Molecular Virology
• ☆ Microbiological Assays
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ Genomics
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Microinjection
• ☆ Mutagenesis
• ☆ Exome Sequencing
• ☆ Recombinant DNA
• ☆ RNA Synthesis
• ☆ RNA Sequencing
• ☆ DNA/Gene Synthesis
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ ChIP-Seq
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Biophysics
• ☆ Histology
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Biomedical Engineering
• ☆ Biological Systems Engineering
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Electron Microscopy
• ☆ Fluorescence Microscopy
• ☆ Nutrition Science
• ☆ Pathogenesis
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Large Scale Cell Culture
• ☆ Cell Surface Receptors
• ☆ Industrial Biotechnology
• ☆ Synthetic Biology
• ☆ Chemical Biology
• ☆ Biomolecular Engineering
• ☆ Gene Synthesis
• ☆ Genetic Engineering
• ☆ Gene Editing/CRISPR
• ☆ Protein/Enzyme Engineering
• ☆ Gene Delivery
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Tissue Engineering
• ☆ Cytometry
• ☆ Cell Aging
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Biosafety Testing
• ☆ Microbiology Testing
• ☆ Bioanalytical Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Pharmaceutical Regulatory Affairs
• ☆ Drug Efficacy Testing
• ☆ Bioavailability
• ☆ Vaccine Development
• ☆ Pharmaceutical Manufacturing
• ☆ Bioprocess Development
• ☆ Biologic & Biosimilar Manufacturing
• ☆ Infectious Disease
• ☆ Viral Diseases
• ☆ Respiratory Syncytial Virus (RSV)
• ☆ Immunotherapy
• ☆ Gene Therapy
• ☆ Drug Delivery Technologies
• ☆ Liposomes
• ☆ Pharmaceutical Technology
• ☆ Stability Testing
• ☆ Shelf-Life Testing
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Literature Search
• ☆ Skills Training
• ☆ Regulatory Writing
• ☆ CMC Documentation
• ☆ NDA/BLA Applications
• ☆ Nonclinical Study Documentation
• ☆ Investigational New Drug (IND) Application Writing
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Grant Writing
• ☆ Formulation
• ☆ Pharmaceutical Formulation

サービス

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Non-Medical Regulatory Writing, Technical Writing

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting, Regulatory Consulting

職務経験

CEO, Founder

Vaxonyx

10月 2025 - 現在

Director

Imunon

10月 2022 - 現在

Senior Scientist

Southern Research

8月 2021 - 10月 2022

Research Scientist III

University of Texas Medical Branch

3月 2017 - 8月 2021

Research Scientist

Chrysalis BioTherapeutics (United States)

6月 2014 - 10月 2016

Research Fellow

National Institute of Allergy and Infectious Diseases

12月 2004 - 5月 2014

学歴

PhD, Biochemistry

CFTRI/University of Mysore

6月 1998 - 12月 2004

M.Sc Biochemistry

Bangalore University

6月 1995 - 5月 1997

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Kempaiah Rayavara, Subeena Sood, Majed M. Matar, Jessica Kim, Meredyth Kinsella, Olivia Signer, John Henderson, Joseph Rogers, Bhavna Chawla, Brandon Narvaez, et al. (2024). Strong immunogenicity & protection in mice with PlaCCine: A COVID-19 DNA vaccine formulated with a functional polymer . Vaccine.

Kempaiah Rayavara, Alexander Kurosky, Yashoda M. Hosakote(2022). Respiratory syncytial virus infection induces the release of transglutaminase 2 from human airway epithelial cells . American Journal of Physiology-Lung Cellular and Molecular Physiology. American Physiological Society

Erol C. Vatansever, Kai S. Yang, Aleksandra K. Drelich, Kaci C. Kratch, Chia-Chuan Cho, Kempaiah Rayavara Kempaiah, Jason C. Hsu, Drake M. Mellott, Shiqing Xu, Chien-Te K. Tseng, et al.(2021). Bepridil is potent against SARS-CoV-2 in vitro . Proceedings of the National Academy of Sciences. 118. (10). Proceedings of the National Academy of Sciences

PREPRINT

Kempaiah Rayavara, Tapas Hazra, Nisha Tapryal, Anirban Chakraborty, Maki Wakamiya, Azharul Islam, Lang Pan, Jason Hsu, Vivian Tat, Junki Maruyama, et al. (2022). The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection .