プロフィール詳細

プロジェクトを作成

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Dr. Khem R.に依頼

India

Prof. & Multi-omics researcher. Expert in biological big data analysis & visualization using R & Python. Bioinfo Lead.

プロフィール概要

I am Associate Professor in the Department of Microbiology with 14 years of integrated research and teaching experience. I lead a research group specializing in the molecular mechanisms of microbial pathogenesis and the application of multi-omics and big data analysis to clinical microbiology. Expertise and Core Skills • Academic Leadership: 14 years of experience in leading research teams, mentoring students, and teaching advanced microbiology and molecular biology courses. • Bioinformatics & Data Science: High proficiency in large-scale omics data analysis and visualization using R. • Multi-Omics Profiling: Expert application of specialized pipelines (Genomics, Transcriptomics, Metagenomics) on a high-performance Linux-based genome analysis workstation. • Molecular Microbiology: Advanced tools in molecular biology for studying antimicrobial resistance, host-pathogen interactions, and microbial pathogenesis. Research Focus & Ongoing Projects My lab is focused on cutting-edge investigations into clinically significant pathogens and complex human health disorders, integrating both wet-lab and computational approaches. 1. Microbial Pathogenesis and Genomics • Pathogen Focus: Investigations into the pathogenesis of clinically significant fungal pathogens, primarily Candida spp. and mucormycosis-causing fungi. • Research Areas: Exploring the mechanisms of antimicrobial resistance and host-pathogen interactions. • Wet-Lab Integration: Comprehensive in vitro and in vivo experimentation, including antifungal screening and nanoparticle synthesis studies. 2. Multi-Omics and Disease Pathophysiology • Integrative Data Analysis: Leading research in microbial genomics, transcriptomics, and the human microbiome. • Complex System Decoding: Utilizing expertise in R and Python to decode complex biological systems and their direct relevance to human health. • Immunological Disorders: Current investigations include the use of integrative multi-omics profiling to provide comprehensive insights into the pathophysiology and host immune responses associated with immune-mediated disorders, such as Kawasaki disease.

専門分野

• ☆ Computational Biology
• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Mycology/Fungi
• ☆ Virology
• ☆ Molecular Virology
• ☆ Biostatistics
• ☆ Mathematical Biology
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ PCR
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Synthetic Genomics
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Exome Sequencing
• ☆ RNA Sequencing
• ☆ Molecular Ecology
• ☆ Pathogenesis
• ☆ Clinical Microbiology
• ☆ Phylogenetics
• ☆ Population Genetics
• ☆ R
• ☆ Urology & Nephrology
• ☆ Dialysis

サービス

• Data & AI

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

職務経験

Associate Professor

Panjab University

8月 2011 - 現在

学歴

PhD (Department of Microbiology)

Panjab University

- 現在

認定資格

• Next Generation Sequencing Technologies : Data Analysis and Applications

  IIT Kharagpur

  10月 2023 - 現在

• Descriptive Statistics with R Software

  IIT Kanpur

  4月 2020 - 現在

出版物

JOURNAL ARTICLE

Khem Raj, Anjali Vijeata, Harshita Ghawri, Ganga Ram Chaudhary, Savita Chaudhary (2025). Engineering fungicidal nitrogen-doped carbon dots from Trillium govanianum rhizomes: A theoretical and experimental approach against Candida auris . Applied Surface Science.

Khem Raj, Nandini Verma, Mohammad Riyaz, Gurkeerat Kaur, Preeti Negi, Harshita Ghawri (2024). Anticandidal Efficacy of Green Synthesized Silver Nanoparticles Using Trans-Himalayan Plant Extracts Against Drug Resistant Clinical Isolates of Candida auris . Indian Journal of Microbiology.

Khem Raj, Preeti Negi, Jatin Chadha, Kusum Harjai, Vijay Singh Gondil, Seema Kumari (2024). Antimicrobial and Antibiofilm Potential of Green-Synthesized Graphene–Silver Nanocomposite against Multidrug-Resistant Nosocomial Pathogens . Biomedicines.

Khem Raj, Preeti Negi, Jatin Chadha, Kusum Harjai, Vijay Singh Gondil, Seema Kumari (2024). Antimicrobial and Antibiofilm Potential of Green-Synthesized Graphene–Silver Nanocomposite against Multidrug-Resistant Nosocomial Pathogens . Biomedicines.

Khem Raj, Aanchal Sharma, Seema Ramniwas, Girish Kumar (2024). Host–pathogen interaction between the African fig fly, <i>Zaprionus indianus</i>, and its external mycobiome under laboratory conditions . Entomologia Experimentalis et Applicata.

Khem Raj, Dhiraj Paul, Praveen Rishi, Geeta Shukla, Dhiraj Dhotre, YogeshSouche (2024). Decoding the role of oxidative stress resistance and alternative carbon substrate assimilation in the mature biofilm growth mode of Candida glabrata . BMC Microbiology.

Khem Raj, Manpreet Dhaliwal, Valliappan Muthu, Arunima Sharma, Shivaprakash M Rudramurthy, Ritesh Agarwal, Harsimran Kaur, Amit Rawat, Surjit Singh, Arunaloke Chakrabarti (2024). Immune and metabolic perturbations in COVID‐19‐associated pulmonary mucormycosis: A transcriptome analysis of innate immune cells . Mycoses.

Khem Raj, Shally Sharma, Mohammad Riyaz, Desh Deepak Singh (2023). Antimicrobial Studies on Garlic Lectin . Probiotics and Antimicrobial Proteins.

Khem Raj, Praveen Rishi, Geeta Shukla, Shivaprakash M. Rudramurhty, Dattatray S. Mongad, Amrita Kaur (2022). Possible Contribution of Alternative Transcript Isoforms in Mature Biofilm Growth Phase of Candida glabrata . Indian Journal of Microbiology.

Khem Raj, Ujjwal Jit Kaur, Adity Chopra, Simran Preet, Kanthi Kiran Kondepudi, Varsha Gupta, Praveen Rishi (2021). Potential of 1-(1-napthylmethyl)-piperazine, an efflux pump inhibitor against cadmium-induced multidrug resistance in Salmonella enterica serovar Typhi as an adjunct to antibiotics . Brazilian Journal of Microbiology.

Praveen Rishi, Khemraj Thakur, Shania Vij, Lavanya Rishi, Aagamjit Singh, Indu Pal Kaur, Sanjay K. S. Patel, Jung-Kul Lee, Vipin C. Kalia (2020). Diet, Gut Microbiota and COVID-19 . Indian Journal of Microbiology.

Rishi, P., Thakur, K., Vij, S., Rishi, L., Singh, A., Kaur, I.P., Patel, S.K.S., Lee, J.-K., Kalia, V.C.(2020). Diet, Gut Microbiota and COVID-19 . Indian Journal of Microbiology. 60. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 420-429.

Anuradha Chakraborti, Subendu Sarkar, Mukul Rastogi, Priyanka Chaudhary, Rajesh Kumar, Priya Arora, Vivek Sagar, InderpalSingh Sahni, Sunil Shethi, Khemraj Thakur, et al. (2017). Association of rheumatic fever &amp; rheumatic heart disease with plausible early &amp; late-stage disease markers . Indian Journal of Medical Research.

Sarkar, S., Rastogi, M., Chaudhary, P., Kumar, R., Arora, P., Sagar, V., Sahni, I.S., Shethi, S., Thakur, K., Ailawadhi, S., et al.(2017). Association of rheumatic fever &amp; rheumatic heart disease with plausible early &amp; late-stage disease markers . Indian Journal of Medical Research. 145. (June). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 758-766.

BOOK CHAPTER

Khem Raj, Mohammad Riyaz (2023). Emerging Microbial Identification Technologies in the Era of OMICS and Genome Editing . Role of Microbes in Sustainable Development.